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We performed curettage followed by autogenous bone grafting in several cases of steroid-related osteonecrosis of the femoral condyle, and reviewed the outcome of this procedure after a mean follow-up of 9.5 years. The number of patients was 4; the mean age at the time of the operation was 30.5 years. The mean Knee Society Objective Score was 52.5 before the operation and had increased to 87.5 at the time of the review. The pre-operative radiographic stages were stage 2 in 2 patients and stage 3 in the other 2 patients. Progression in the disease stage was observed in 3 patients. MRI revealed survival of the grafted bone in only one case, and collapse of the articular surface in all cases. In conclusion, though the clinical results showed improvement, the autogenous bone graft failed to answer the purpose of preventing the progression in disease stage.
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http://dx.doi.org/10.2739/kurumemedj.51.277 | DOI Listing |
Int J Biol Macromol
September 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, PR China. Electronic address:
Due to the poor regeneration ability of cartilage tissue, the design and fabrication of permanent hydrogel cartilage scaffolds with mechanical properties matching is still an urgent challenge. In this study, we propose an "inner swelling-outer restraint" strategy to construct Janus hydrogel for pressure-bearing cartilage replacement, which is inspired by the "Lamina-splendens" structure of cartilage. As a proof of concept, the poly(vinyl alcohol)/carboxymethyl cellulose sodium (PVA/CMCNa) layer is designed to capture more fluid by introducing negatively charged aggregates, while the macromolecular conformation of the PVA/MoS layer can be densified through wet annealing, thereby increasing the liquid permeation resistance of the PVA/CMCNa layer.
View Article and Find Full Text PDFJ Endod
September 2025
Department of Periodontology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. Electronic address:
Severe periapical cysts frequently result in tooth loss with concomitant severe alveolar bone destruction, precluding immediate implant placement. Autogenous tooth transplantation (ATT), which involves transplanting the patient's own tooth to the recipient site, offers a biological approach to reconstruct both the dentition and supporting bone structures. This report presents a 25-year-old female with a mobile, discolored maxillary right lateral incisor (#12) exhibiting grade 3 mobility due to a large periapical cyst (extending to #14 on CBCT) with root developmental arrest, secondary to Oehlers type II dens invaginatus.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Insufficiency periprosthetic fractures after total knee arthroplasty are uncommon, typically nontraumatic events; however, clinical outcome data on their surgical management remain limited. We retrospectively reviewed 21 patients (18 women, 3 men; mean age = 76 years) who sustained femoral or tibial insufficiency periprosthetic fractures between November 2016 and January 2022 and underwent revision total knee arthroplasty with stemmed components augmented by bulk femoral-head allografts and autologous bone graft. Five patients with preoperative valgus alignment presented medial condylar fractures, whereas sixteen patients with varus deformity exhibited ten lateral and 6 medial condylar fractures.
View Article and Find Full Text PDFUnfallchirurgie (Heidelb)
August 2025
Klinik für Unfallchirurgie und Orthopädie, BG Klinik Ludwigshafen, Ludwig-Guttmann-Str. 13, 67071, Ludwigshafen am Rhein, Deutschland.
Bone defects in the limbs may result from trauma, debridement during osteitis or pseudarthrosis resection or tumors [1]. Treating bone defects of the femur and tibia poses a substantial challenge in trauma surgery and orthopedics. Interdisciplinary orthoplastic treatment combined with soft tissue reconstruction is often necessary to preserve the extremity and its function.
View Article and Find Full Text PDFJ Am Podiatr Med Assoc
August 2025
*Department of Orthopedics and Traumatology, Bezmialem Vakif University, Istanbul, Turkey.
Primary malignancies originating in the calcaneus are rare, constituting fewer than 1% of skeletal tumors. Traditional approaches like amputation, though effective, result in significant morbidity. This study presents a case of a 32-year-old male with calcaneal chondrosarcoma, managed with total calcanectomy and subsequent limb salvage through iliac wing autograft reconstruction.
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