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Attention-deficit/hyperactivity disorder in adults with epilepsy: Preliminary prevalence and associated factors in a Czech sample.
Epilepsy Res
August 2025
Department of Nursing, 2nd Medical Faculty, Charles University, Prague, Czech Republic; Department of Clinical Psychology, University Hospital Kralovske Vinohrady, Prague, Czech Republic. Electronic address:
Objective: This study investigated the prevalence of Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in Czech adult people with epilepsy (PWE) and examined factors potentially contributing to the co-occurrence of these two conditions. Although previous research has consistently reported elevated rates of ADHD in epilepsy populations, data from adult samples in Czech Republic remain limited.
Methods: Fifty-six adults with epilepsy completed validated self-report questionnaires assessing ADHD symptoms (ASRS), anxiety (GAD-2), and depression (NDDIE-2).
Recursive splice sites are rare motifs postulated to facilitate splicing across massive introns and shape isoform diversity, especially for long, brain-expressed genes. The necessity of this unique mechanism remains unsubstantiated, as does the role of recursive splicing (RS) in human disease. From analyses of rare copy number variants (CNVs) from almost one million individuals, we previously identified large, heterozygous deletions eliminating an RS site (RS1) in the first intron of that conferred substantial risk for attention deficit hyperactivity disorder (ADHD) and other neurobehavioral traits.
View Article and Find Full Text PDFComparative analysis of stress levels and coping strategies in parents of neurodivergent and neurotypical children.
Front Child Adolesc Psychiatry
August 2025
Faculty of Medicine, Veracruzana University, Minatitlan, Mexico.
Parents of children with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) face unique challenges that may significantly increase stress levels, potentially impacting the emotional well-being of the entire family. In Mexico, limited research has examined the association between parental stress and coping strategies among families with children with developmental disabilities. This study aimed to compare stress levels and coping strategies among parents of children with ASD, ADHD, and neurotypical developing (NTD) children, as well as to analyze differences in coping styles across these groups.
View Article and Find Full Text PDFADHD diagnostics and severity assessment using topological manifold learning of resting-state functional magnetic resonance imaging (rs-fMRI).
Neuroimage Rep
September 2025
Arizona State University, Tempe, AZ, 85287, USA.
Non-intrusive neuroimaging technology offers fast and robust diagnostic tools for neuro-disorder disease diagnosis, such as Attention-Deficit/Hyperactivity Disorder (ADHD). Resting-state functional magnetic imaging (rs-fMRI) has been demonstrated to have great potential for such applications due to its unique capability and convenience in providing spatial-temporal brain imaging. One critical challenge of using rs-fMRI data is the high dimensionality for both spatial and temporal domains.
View Article and Find Full Text PDFExamining for race-associated differences on Sway Medical System balance and cognitive tests used for sport-related concussion.
Front Neurol
August 2025
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, United States.
Background: Race associated differences and disparities in test scores, such as on neuropsychological measures, can complicate the interpretation of these test scores in student athletes following a concussion. It is unknown if there are race associated differences on the Sway Medical System, a battery that includes balance and cognitive tests for use in concussion management.
Purpose: To determine if there are race-associated differences in Sway Medical System balance and cognitive module scores among athletes undergoing preseason baseline testing.