98%
921
2 minutes
20
Objective: In rats the available techniques for evaluation of sensory nerve conduction are limited. We report a new method of sensory nerve conduction of the plantar nerve using needle electrodes as the recording electrodes behind the medial malleolus and ring electrodes as the stimulating electrodes around the three middle toes.
Methods: We performed this sensory nerve conduction test in 25 rats during their growth over a 6 weeks' period and compared this method with the motor nerve conduction and H-reflex sensory nerve conduction of the tibial nerve in 10 rats, and with the motor and mixed nerve conductions of the tail nerve in 15 rats.
Results: There was a highly or moderately significant correlation between the body weight and sensory nerve conduction velocity (NCV) of the plantar nerve, mixed NCV and motor NCV of the tail nerve, indicating a growth-related increase in the NCV. The growth-related increase in the NCV was not observed in the motor and H-reflex sensory nerve conductions of the tibial nerves.
Conclusions: This test is simple and reliable and can be used for the sensory nerve conduction test in rats.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.clinph.2004.02.007 | DOI Listing |
Commun Biol
September 2025
Division of Neurobiology, Faculty of Biology, Ludwig-Maximilians-Universität München, Planegg - Martinsried, Germany.
The internal resistance of axons to ionic current flow determines action potential conduction velocity. Although mitochondria support axonal function, axons have been modeled as organelle-free cables, and mitochondrial impact on conduction velocity, specifically by increasing internal resistance, remains understudied. We combine computational modeling and electron microscopy of forebrain premotor axons controlling birdsong production.
View Article and Find Full Text PDFMetab Brain Dis
September 2025
Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, 443002, Hubei, China.
Demyelinating diseases, a prevalent group of neurological disorders, lead to impaired nerve conduction and sensorimotor dysfunctions. Despite existing treatments demonstrating some efficacy, their limitations have driven research toward exploring natural remedies. This review summarizes the therapeutic potential of four traditional tonic Chinese herbal medicines-ginsenosides, deer antler polypeptides, resveratrol, and ginkgo leaf extracts-for demyelinating diseases.
View Article and Find Full Text PDFCureus
August 2025
Department of Internal Medicine, Hamad Medical Corporation, Doha, QAT.
Peroneal neuropathy is a recognized cause for foot drop, typically following trauma, nerve damage, immobilization, or prolonged external pressure. Recently, rapid weight loss after bariatric surgery has been recognised as a potential cause for peroneal neuropathy. This may be due to the loss of protective fat tissue near the peroneal nerve, increasing its susceptibility to compression.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neurosurgery, Xingtai Ninth Hospital, Xingtai, China.
Introduction: The aim of this study was to evaluate the clinical outcomes of spinal cord stimulation (SCS) in patients with painful diabetic peripheral neuropathy (PDPN).
Materials And Methods: Ninety-two patients underwent permanent SCS implantation and completed a 6-month post-operative follow-up. The primary endpoint was patient amputation rate, and secondary endpoints included Quality of Life (QOL LC V2.
Mater Today Bio
October 2025
Department of Reproductive Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.
Clinically, even in patients diagnosed with non-obstructive azoospermia, spermatogenesis may be present in some seminiferous tubules, which gives the patient hope of having biological offspring of his own. However, there is still a blank for high-precision detection technologies to support accurate diagnosis and effective treatment. In this work, we successfully developed a minimally invasive fine needle detection memristive device that features a structure composed of Ag/CH-MnO/FTO by utilizes the organic-inorganic heterojunction as functional layer.
View Article and Find Full Text PDF