Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
In the presence of an equimolar amount of InCl(3), 8-tributylstannyl-6-octen-1-ynes (allylstannanes bearing an alkynyl group) were efficiently cyclized to 2-allyl-1-methylenecyclopentanes. In contrast, catalytic use of InCl(3) gave 2-allyl-1-(tributylstannylmethylene)cyclopentanes mainly by intramolecular allylstannylation. These cyclizations could proceed via intramolecular addition of an allylindium intermediate.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jo035780j | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Polymorphic RNA-Templated Modulation of Photophysics and Dynamics of a Molecular Rotor with Contrasting Affinity: A Demonstration of Sequential Energy Transfer-Triggered Bright White Light Generation.
Langmuir
September 2025
Biophysical Chemistry Laboratory, Physical Chemistry Section, Department of Chemistry, Jadavpur University, Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, India.
Photophysical studies on the interaction of small molecules with various forms of nucleic acids are attracting attention nowadays in order to delineate the molecular level mechanism of various biological processes occurring in vivo. Herein, we employed vivid steady-state and time-resolved spectroscopic techniques to elucidate the detailed characterization of the binding interaction of a biologically active cationic dye thioflavin T (ThT) with double and triple helical forms of RNA - A.U duplex and U.
View Article and Find Full Text PDFAlbumin Binding Enhances the Lysosomal β-Galactosidase Sensitivity of Fluorogenic Probes Characteristic of Intramolecular Charge Transfer.
ACS Appl Bio Mater
September 2025
Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Rd, Sha
Glycosidases generally function in specific organelles to hydrolyze glycoconjugates. Thus, the in situ visualization of glycosidase activities in an organelle-targeted manner can help to better delineate their biological functions. Lysosomal β-galactosidase (β-Gal) is reported to be a biomarker for ovarian cancer and cellular senescence.
View Article and Find Full Text PDFMultifunctional Binding Interface Drives Near-Unity CO Selectivity in Acidic CO Electrolysis.
Angew Chem Int Ed Engl
September 2025
Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, 21218, USA.
The electrocatalytic carbon dioxide (CO) reduction is challenged by the parasitic hydrogen evolution reaction (HER) especially in acidic media. Here, we elaborate that redox-active isoindigo, acting as a multifunctional co-catalyst, can pre-activate CO-bound intermediates and suppress HER upon the synergistic effects of Lewis acid-base adduct formation, intramolecular hydrogen-bond interaction, and interfacial water structure modulation. Modifying a silver catalyst with isoindigo substantially decreases the energy barrier for CO-to-*COOH conversion, which is regarded as the potential-limiting step of carbon monoxide production.
View Article and Find Full Text PDFPalladium-Catalyzed [4+1] Cycloaddition of 3,3-Difluoropent-4-en-2-ones with Amines: A Modular Approach to 3-Fluoropyrroles.
Org Lett
September 2025
School of Pharmacy and Food Engineering, Wuyi University, Jiangmen 529090, P. R. China.
3-Fluoropyrroles are privileged scaffolds in pharmaceutical and agrochemical applications, yet their synthesis remains challenging. Herein, we report a palladium(0)-catalyzed [4+1] cycloaddition/dehydration strategy for the efficient construction of 3-fluoropyrroles from readily available 3,3-difluoropent-4-en-2-ones and primary amines. This transformation proceeds via C-F bond activation to generate a key π-allyl-Pd(II) intermediate, followed by intramolecular addition/dehydration to furnish the heterocyclic core.
View Article and Find Full Text PDFMonitoring Receptor Clustering by Aggregation-Induced Emission.
Chempluschem
September 2025
Faculty of Chemistry, University of Duisburg-Essen, Universitätsstraße 7, 45117, Essen, Germany.
This study introduces a simple signal transduction system that mimics the receptor tyrosine kinase mechanism by employing amphiphilic receptors embedded in lipid bilayers. The designed receptors carry bisphosphonate head groups and feature aggregation-induced emission enhancement (AIEE) properties. Upon addition of polyammonium messengers, they undergo ligand-induced dimerization or clustering inside the membrane.
View Article and Find Full Text PDF