Publications by authors named "Zorana J Andersen"

Background: Increasing evidence associates air pollution with dementia, but some pollutants and susceptible groups are understudied.

Methods: We followed all Danish residents aged ≥60 years as of 1-1-2000, without prior dementia, until 12-31-2018 for dementia incidence identified via hospital contact or prescription. We assessed annual mean levels of fine particulate matter (PM), nitrogen dioxide (NO), and black carbon (BC) in 2010 utilizing European-wide hybrid land-use regression models, at baseline (2000) residential addresses.

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Introduction: Short-term exposure to ultrafine particles (UFP; <100 nm) may trigger respiratory hospitalizations, potentially even more so among children than adults, but available evidence is limited. We examined the association between short-term UFP exposure and respiratory infection hospital admissions in children in Copenhagen, Denmark.

Methods: Daily concentrations of UFP were monitored at an urban background station during 2002-2018.

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Background: Patient-based cohorts were frequently used to investigate air pollution-related coronavirus disease 2019 (COVID-19) evidence, which can be subject to collider bias. However, this bias has not been explored. We aimed to quantify and adjust the collider bias by limiting study population to patients with COVID-19 when estimating the association between long-term exposure to air pollution (LTAP) and COVID-19 mortality.

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Airports are major sources of ultrafine particles (UFP), raising health concerns among people living in immediate proximity. However, little is known about UFP concentrations in residential areas around airports. In this study, we mapped UFP exposure concentrations in a residential area nearby Copenhagen International Airport (CPH).

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Background: Ultrafine particles (UFP; <0.1 µm in diameter) are not regulated or commonly monitored but may be harmful to human health, particularly for children. In this study, we aimed to examine the association between short-term exposure to UFP and asthma hospital admissions in children.

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Long-term exposure to air pollution has been linked with acute lower respiratory infections (ALRIs) in children, but the evidence in adults is still mixed and sparse. We aimed to examine the association between long-term exposure to air pollution and incident ALRIs in adults. We followed all Danish residents aged ≥30 years ( = 3,083,227) for the first-ever hospital contact (inpatient, outpatient, or emergency) for ALRIs (and pneumonia or influenza separately) from 2000 to 2018.

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Introduction: Ambient air pollution and road traffic noise are stroke risk factors, but evidence on their potential joint effects remains limited. This study investigated the independent and joint associations of air pollution and road traffic noise on stroke incidence using both multiplicative and additive scales.

Methods: We followed stroke incidence in ten cohorts in Sweden, Denmark, and Finland.

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Policies to implement climate-forcing pollution emission reductions have often been stymied by economic and political divisiveness. However, certain uncontested nonregret public health policies that also carry climate-forcing cobenefits with them could provide more achievable policy pathways to accelerate the implementation of climate mitigation. An International Society for Environmental Epidemiology Policy Committee endorsed pre-28th Conference of the Parties climate meeting workshop brought together experts on environment, diet, civic planning, and health to review current understanding of public health policy approaches that provide climate change mitigation cobenefits by also reducing greenhouse gas emissions.

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Purpose: Whether breast density mediates associations between early life body size and pubertal timing with postmenopausal breast cancer is underexplored.

Methods: We studied 33,939 Danish women attending the Capital Mammography Screening Program at ages 50-69 years. Early life anthropometry and pubertal timing information came from the Copenhagen School Health Records Register.

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Article Synopsis
  • The study investigates the link between residential greenspace and the impact of COVID-19 on health, focusing on Danish adults 50 and older during the pandemic.* -
  • Researchers found that increased greenspace was associated with lower rates of COVID-19 infection, hospitalization, and mortality, especially among vulnerable groups like the elderly and those with chronic illnesses.* -
  • Health impact assessments suggested that enhancing local greenspace could have potentially prevented 8-14% of COVID-19 cases in the population studied, indicating benefits of greening initiatives.*
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Ultrafine particles (UFP), commonly expressed as particle number concentrations (PNC), have been associated with harm to human health yet are currently not regulated or routinely monitored in many places. This has limited the potential for studies of health effects of long-term exposure to UFP. The present study aims to understand the spatial and temporal variation in façade-level UFP exposures in Copenhagen, Denmark.

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Article Synopsis
  • * Using advanced statistical models, researchers analyzed data over a significant follow-up period, revealing that lung cancer incidence was positively linked to fine particulate matter (PM), nitrogen dioxide (NO₂), and black carbon (BC), while showing a negative association with ozone (O) which flipped after adjusting for NO.
  • * The results indicated that the increased risk of lung cancer incidence was nearly as strong as that for mortality, with both associations remaining significant even at lower pollution levels, suggesting that air quality should be a crucial public health consideration.
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Article Synopsis
  • This study investigated the relationship between transportation noise and atrial fibrillation (AF) using data from 11 Nordic cohorts, totaling over 161,000 participants.
  • Researchers found that higher road traffic noise exposure is linked to an increased risk of developing AF, particularly in women and overweight individuals.
  • Aircraft noise also showed a potential association with AF risk, while railway noise did not appear to be related; overall, road and aircraft noise combined raised the risk significantly.
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Background: Few cohort studies have examined the associations of natural surroundings (green and blue space) with cardiovascular disease (CVD) and show mixed findings. We aimed to investigate the associations between long-term exposure to green and blue space and incidence of CVD in the Danish Nurse Cohort.

Methods: We followed 19,070 female nurses living in Denmark from 1993/1999 to 2018.

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Background: Available evidence suggests a link between exposure to transportation noise and an increased risk of obesity. We aimed to assess exposure-response functions for long-term residential exposure to road traffic, railway and aircraft noise, and markers of obesity.

Methods: Our cross-sectional study is based on pooled data from 11 Nordic cohorts, including up to 162,639 individuals with either measured (69.

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Background: Long-term exposure to road traffic noise is associated with cardiovascular disease, but the evidence on respiratory diseases is just emerging. We aimed to examine the association between long-term exposure to road traffic noise and the incidence of acute lower respiratory infections (ALRIs) in adults.

Methods: We followed 23,141 female nurses (age ≥ 44 years) from the Danish Nurse Cohort from baseline (1993 or 1999) to their first hospital contact (inpatient, outpatient, or emergency room) for ALRI, death, emigration or the end of 2015.

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Objectives: We evaluated studies that used the World Health Organization's (WHO) AirQ and AirQ+ tools for air pollution (AP) health risk assessment (HRA) and provided best practice suggestions for future assessments.

Methods: We performed a comprehensive review of studies using WHO's AirQ and AirQ+ tools, searching several databases for relevant articles, reports, and theses from inception to Dec 31, 2022.

Results: We identified 286 studies that met our criteria.

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Introduction: We examined the association of long-term exposure to air pollution and road traffic noise with dementia incidence in the Danish Nurse Cohort.

Methods: Female nurses were followed for dementia incidence (hospital contact or medication prescription) from 1993/1999 to 2020. Air pollution and road traffic noise levels were estimated at nurses' residences, and their associations with dementia were examined using Cox regression models.

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Despite the known link between air pollution and cause-specific mortality, its relation to chronic kidney disease (CKD)-associated mortality is understudied. Therefore, we investigated the association between long-term exposure to air pollution and CKD-related mortality in a large multicentre population-based European cohort. Cohort data were linked to local mortality registry data.

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Air pollution is a major risk factor for chronic cardiorespiratory diseases, affecting the immune and respiratory systems' functionality, but epidemiological evidence in respiratory infections remains sparse. We aimed to assess the association of long-term exposure to ambient air pollution with the risk of developing new and recurrent acute lower respiratory infections (ALRIs), characterized by persistently severe symptoms necessitating hospital contact, and identify the potential susceptible populations by socioeconomic status, smoking, physical activity status, overweight, and comorbidity with chronic lung disease. We followed 23,912 female nurses from the Danish Nurse Cohort (age >44 yr) from baseline (1993 or 1999) until 2018 for incident and recurrent ALRIs defined by hospital contact (inpatient, outpatient, and emergency room) data from the National Patient Register.

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Ultrafine particles (UFPs) are airborne particles with a diameter of less than 100 nm. They are emitted from various sources, such as traffic, combustion, and industrial processes, and can have adverse effects on human health. Long-term mean ambient average particle size (APS) in the UFP range varies over space within cities, with locations near UFP sources having typically smaller APS.

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Recent research suggests a link between air pollution and cognitive development in children, and studies on air pollution and academic achievement are emerging. We conducted a nationwide cohort study in Denmark to explore the associations between lifetime exposure to air pollution and academic performance in 9th grade. The study encompassed 785,312 children born in Denmark between 1989 and 2005, all of whom completed 9th-grade exit examinations.

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