Electrochemical hydrogenation of furfural for synthesis of furfuryl alcohol over copper oxide catalytic electrode.

Furfural (FF) is a biomass-derived platform molecule characterized by an aldehyde group attached to a furan ring. The selective electrochemical hydrogenation (ECH) of the aldehyde group into hydroxymethyl offers a sustainable approach for converting FF into valuable furfuryl alcohol (FA) chemical. Efficient catalyst that balances active hydrogen (H*) generation and FF adsorption is crucial for electrochemical FF-to-FA conversion.

SbSemicrowires/ZnO nanoparticles heterojunction for high performances self-powered photodetector.

Self-powered photodetectors play a crucial role in technology, garnering attention for their diverse applications. However, most current models face challenges such as reliance on external power, complex fabrication, and inconvenient usability. SbSepresents a promising solution for p-type semiconductors in photovoltaic cells, owing to ideal bandgap and excellent light absorption.

Integrating weighted gene co-expression network analysis and machine learning to elucidate neural characteristics in a mouse model of depression.

Introduction: An AI-assisted deep learning strategy was applied to analyze the neurobiological characteristics of depression in mouse models. Integration of weighted gene co-expression network analysis (WGCNA) with the random forest algorithm enabled the identification of critical genes strongly associated with depression onset, offering theoretical support and potential biomarkers for early diagnosis and precision treatment.

Methods: Gene expression data from depression-related mouse models were obtained from public GEO datasets (e.

Incidence of human sapovirus outbreaks in Beijing, China, 2014-2021: predominance of genotypes GII.3 and GI.2.

The study aimed to analyze epidemiological, clinical, and genome characteristics of acute gastroenteritis (AGE) outbreaks caused by sapovirus in Beijing. Epidemiological and clinical characteristics of sapovirus detected by RT-qPCR were collected from AGE surveillance. Descriptive statistics were used for epidemiological analysis, and both genotype identification and sequence analysis were conducted on the VP1 regions, RNA-dependent RNA polymerase regions, and whole genomes.

Correlations between gene polymorphisms, cognitive function, and activities of daily living among elderly patients with Alzheimer's disease.

Background: Single nucleotide polymorphisms (SNPs) of gene are associated with cognitive function while ghrelin is associated with Alzheimer's disease (AD).

Aim: To determine the relationship between SNPs, cognitive function, and activities of daily living (ADLs) in elderly AD patients.

Subjects And Methods: This study included 100 elderly AD patients as the AD group, and 72 elderly healthy patients as the control group.

Initial Establishment of Warning Model for Epidemic Intensity of Norovirus GII Associated with Acute Gastroenteritis in Beijing Based on Synthetic Index Method.

At present, there is no research that classifies the epidemic intensity of acute gastroenteritis (AGE) caused by Norovirus (NoV) GII combined cases and environmental surveillance data at the same time. With reference to the experience of the epidemiological-level classification of infectious disease and the actual epidemiological status of NoV AGE in Chaoyang District, Beijing, China, the epidemic intensity of NoV GII was divided into five grades with increasing intensity from grade 1 to grade 5, which corresponds to non-epidemic risk, general risk, moderate risk, high risk, and ultra-high risk, respectively. If the synthetic index of two consecutive monitoring weeks in the epidemic season of 2023-2024 exceeds a certain threshold, an early warning for the corresponding epidemic intensity will be issued and recommendations on the corresponding control measures will be given.

Self-supported copper-cobalt oxide hybrid electrode for bifunctionally electrocatalytic nitrate reduction and methanol oxidation reactions.

Electrochemical nitrate reduction reaction (NORR) to ammonia (NH) is a sustainable approach to upcycle nitrate (NO) pollutant, the further pairing of cathodic NORR with anodic methanol oxidation reaction (MOR) enables coproduction of NH and formate chemicals by electrolysis at enhanced energy efficiency. Bifunctional catalytic electrode for both reactions is crucial for achieving such a target. In view of the strong NO adsorption ability of copper (Cu) and the high active hydrogen adsorption ability of cobalt (Co) based compound, the catalyst composed of Cu and Co elements facilitates the deoxidation and complete hydrogenation of NO into NH.

Joint association of TyG index and LDL-C with all-cause and cardiovascular mortality among patients with cardio-renal-metabolic disease.

Both triglyceride-glucose (TyG) index, as a surrogate marker of insulin resistance, and low-density lipoprotein cholesterol (LDL-C) are independent risk factors for long-term prognosis among patients with cardio-renal-metabolic (CRM) disease. However, the co-exposures of TyG index and LDL-C to mortality is unclear. The aim of this study is to investigate the joint effects and risk stratification of the TyG index and LDL-C on all-cause and cardiovascular mortality in CRM patients.

ESM1 promote proliferation, invasion and angiogenesis via Akt/mTOR and Ras pathway in kidney renal clear cell carcinoma.

The most common types of renal carcinoma is kidney renal clear cell carcinoma (KIRC). ESM1 is a secreted protein, which involved in, lipids and glucose metabolism, but their role in angiogenesis is contradictory in different disease, especially in KIRC. Bioinformatic analysis confirmed the ESM1 expression and prognosis in KIRC.

The bile acid metabolome in umbilical cord blood and meconium of healthy newborns: distinct characteristics and implications.

Objective: To characterize the bile acid metabolomic profiles of umbilical cord blood and meconium in healthy newborns.

Methods: Fifteen healthy newborns, which born in the Obstetrics Department of the Affiliated Hospital of Southwest Medical University between July 1 and August 31, 2023, were selected as study subjects. Umbilical cord blood and meconium samples were collected, and bile acid metabolomics were analyzed using ultra-high performance liquid chromatography-tandem mass spectrometry.

Bismuth oxychloride-bismuth oxide hybrid as a high-capacity anode material for aqueous alkaline battery.

A high-capacity and rate capability anode material is highly desired to improve the export performance of aqueous alkaline batteries (AABs). Due to the 3-electrons redox chemistry within a wide negative potential range, bismuth (Bi) based compounds are promising candidates as anode materials in AABs. A hybrid composed of different Bi-based compounds is envisioned to further reinforce the faradaic activity and affinity for electrolyte ions, thereby maximizing the charge storage capacity.

Single-atom "surgery" on chiral all-dialkynyl-protected superatomic silver nanoclusters.

The manipulation of single atom within the metallic kernel of nanoclusters has attracted considerable attention due to its potentials to elucidate kernel-based structure-property relationships at the single-atom level. Herein, new-designed chiral bialkynyl ligands, have been chosen as protective agents to isolate two pairs of 8-electron superatomic silver nanoclusters, R/S-Ag39 and R/S-Ag40. X-ray diffraction analysis reveals that Ag39 and Ag40 with the same number of chiral ligands, possess a closely analogous silver skeleton but a single-atomic difference.

Association of stress hyperglycemia ratio with presence and severity of chronic kidney disease among US adults with diabetes mellitus.

Background: Among diabetes mellitus (DM) patients, stress hyperglycemia ratio (SHR) is a strong predictor of short- and long-term prognosis, and adverse cardiovascular events. However, whether SHR is associated with increased risk of presence and severity of chronic kidney (CKD) disease remains undetermined.

Methods: Patients with DM from the National Health and Nutrition Examination Survey (NHANES) database (1999-2020) were included and divided into 5 groups according to their SHR level (quintile 1 to 5).

Epitaxial Growth of Silver Clusters from Ag57 to Ag72 via Laminating Multiple Different Anion Templates.

The established capability of anion templates in precisely manipulating the size, geometry, and function of metal clusters is well acknowledged. However, the development of a systematic methodology for orchestrating the assembly of silver clusters, particularly those encompassing multiple distinct types of anion templates, remains elusive due to the formidable synthetic challenge. In this work, we report two novel silver clusters, Ag57 and Ag72, using two and three different anion templates, respectively.

The RING-Type E3 Ligase BOI Interacts with EXO70E2 and Mediates Its Ubiquitination in .

The exocyst is a hetero-octameric complex that exhibits significant functional diversity in regulating biological processes and defense responses. In plants, the EXO70 proteins are important components of the exocyst complex and are involved in membrane trafficking, biotic and abiotic interactions, as well as cell wall formation. A previous study has indicated that a member of the EXO subfamily, EXO70E2, interacts with RIN4 to mediate plant immunity.

Preparation of alkyl microporous organic network-based capillary column for an efficient gas chromatographic separation of position isomers.

The large surface area, excellent thermal stability and easy modification make microporous organic networks (MONs) good candidates in the field of gas chromatography (GC). Due to the limited species and highly conjugated networks of MONs, their applications are still in infancy and restricted. To accelerate their developments and to enrich their types in GC, here we report the first example of synthesizing alkyl MON and its capillary column for GC separation of position isomers.

Efficacy of music therapy for pain control of extracorporeal shock wave lithotripsy: A meta-analysis of randomized controlled studies.

Introduction: Music therapy may have some potential in the pain control of extracorporeal shock wave lithotripsy, and this meta-analysis aims to study the analgesic efficacy of music therapy for extracorporeal shock wave lithotripsy.

Methods: We have searched several databases including PubMed, EMbase, Web of Science, EBSCO and Cochrane Library databases, and selected the randomized controlled trials (RCTs) comparing the efficacy of music therapy for pain control of extracorporeal shock wave lithotripsy. This meta-analysis was conducted using the random-effect or fixed-effect model based on the heterogeneity.

Risk Factors for Norovirus Outbreaks in Schools and Kindergartens - Beijing Municipality, China, July 2017-June 2022.

What Is Already Known On This Topic?: Norovirus is the leading cause of global acute gastroenteritis outbreaks. Norovirus outbreaks mainly occur in schools and kindergartens in China, always causing public health issues.

What Is Added By This Report?: Conditional logistic regression method was used to analyze the risk factors for norovirus outbreaks in schools and kindergartens, and found that students vomiting at school or kindergarten, case activity in public areas, and the first case's classroom less than 5 meters from toilets were risk factors.

Association of Systemic Inflammation Level on Admission with Total and Cardiovascular‑Specific Death in Heart Failure with Preserved Ejection Fraction: A Large Multi‑Center Retrospective Longitudinal Study.

Purpose: Heart failure with preserved ejection fraction (HFpEF) is inherently a complex inflammatory syndrome, and heightened inflammation is strongly associated with an increased risk of death. However, the association of systemic inflammation levels with total and cardiovascular death among patients with HFpEF remains unknown. We aimed to investigate the prognostic impact of systemic inflammation on all-cause and cardiovascular death among patients with HFpEF.

Rotavirus outbreaks in China, 1982-2021: a systematic review.

Background: Rotavirus is globally recognized as an important cause of acute gastroenteritis in young children. Whereas previous studies focused more on sporadic diarrhea, the epidemiological characteristics of rotavirus outbreaks have not been systematically understood.

Methods: This systematic review was carried out according to the Preferred Reporting Items for Systematic Review and Meta-Analysis standards, WANFANG, China National Knowledge Infrastructure (CNKI), PubMed, and Web of Science databases were searched from database inception to February 20, 2022.

Vanadium-Silsesquioxane Nanocages as Heterogeneous Catalysts for Synthesis of Quinazolinones.

The functionalization of polyoxovanadate clusters is promising but of great challenge due to the versatile coordination geometry and oxidation state of vanadium. Here, two unprecedented silsesquioxane ligand-protected "fully reduced" polyoxovanadate clusters were fabricated via a facial solvothermal methodology. The initial mixture of the two polyoxovanadate clusters with different colors and morphologies (green plate and blue block ) was successfully separated as pure phases by meticulously controlling the assembly conditions.

Molybdenum iron carbide-copper hybrid as efficient electrooxidation catalyst for oxygen evolution reaction and synthesis of cinnamaldehyde/benzalacetone.

Oxygen evolution reaction (OER) is the efficiency limiting half-reaction in water electrolysis for green hydrogen production due to the 4-electron multistep process with sluggish kinetics. The electrooxidation of thermodynamically more favorable organics accompanied by CC coupling is a promising way to synthesize value-added chemicals instead of OER. Efficient catalyst is of paramount importance to fulfill such a goal.