Deep neural network-based joint monitoring of carrier-to-signal power ratio (CSPR) and optical signal-to-noise ratio (OSNR) for directly detected optical single-sideband transmission.

Optical single-sideband (SSB) transmission enhances spectral efficiency and mitigates transmission reach limitations caused by chromatic dispersion (CD), making it ideal for cost-effective data-center interconnects. This paper proposes and demonstrates deep neural network (DNN)-enabled optical performance monitoring (OPM) for optical SSB transmissions. By extracting features dependent on both carrier-to-signal power ratio (CSPR) and optical signal-to-noise ratio (OSNR) from amplitude histograms (AHs) generated by an AC-coupled photodetector (PD) and an analog-to-digital converter (ADC), a low-complexity dual-task DNN (DT-DNN) is employed to jointly estimate CSPR and OSNR with high accuracy.

Prognostic value of platelet to lymphocyte ratio in patients with cervical cancer: an updated systematic review and meta-analysis.

Background: The identification of biomarkers that reliably forecast cervical cancer (CC) outcomes is a key area of research. Several studies have explored the link between the platelet-to-lymphocyte ratio (PLR) and cervical cancer prognosis, though the results are not entirely conclusive.

Methods: PubMed, Embase, Web of Science, and the Cochrane Library were used to search, with studies published up to May 30, 2024.

Identification of a potential miRNA-mRNA regulatory network for ischemic stroke by using bioinformatics methods: a retrospective study based on the Gene Expression Omnibus database.

Background: Ischemic stroke (IS), a leading cause of disability and death worldwide, lacks effective biomarkers for early diagnosis and therapeutic intervention. This study aims to explore the potential miRNA-mRNA regulatory network in IS using clinical samples and bioinformatics methods, providing insights into its pathophysiology and identifying novel biomarkers.

Methods: We analyzed plasma samples from IS patients and controls collected at Ningbo No.

Experimental determination of giant polarization in wurtzite III-nitride semiconductors.

Polarization engineering has revolutionized the photonic and electronic landscape of III-nitride semiconductors over the past decades. However, recent revelations of giant ferroelectric polarization in wurtzite III-nitrides challenge the long-standing paradigms. Here, we experimentally elucidate the polarization, including its magnitude and orientation, and its relationship to lattice polarity in III-nitrides.

Development of a Maternal Health Care Exercise and Pelvic Abdominal Rehabilitation Curriculum for Obstetric Medical Professionals Using a Modified Delphi Process.

Introduction And Hypothesis: The purpose of this study was to develop a maternal health care exercise and pelvic abdominal rehabilitation curriculum for obstetric medical professionals. Maternal health care exercise and pelvic abdominal rehabilitation can effectively prevent and alleviate pelvic-floor-rehabilitation problems in pregnant women and improve their quality of life. However, there is a lack of standardized courses for training obstetric medical professionals.

Depressive and anxiety symptoms during adolescence: The protective roles of adolescent and family assets within ECHO's diverse national population.

To understand the factors that preserve mental health amongst a diverse population of adolescents, we examined links between neighborhood-level resources, adolescents' self-reported personal assets (low perceived stress, meaning and purpose, life satisfaction), parent-reported family assets (household income, maternal mental health) and adolescents' self-reported depressive and anxiety symptoms. Participants included a racially and ethnically diverse national sample of 4325 adolescents (10 - 21 years) from the Environmental influences on Child Health Outcomes (ECHO) program. Neighborhood-level resources were not directly associated with depressive or anxiety symptoms.

The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.

Objective: Vitamin D(VitD) deficiency has been found prevalent among patients with thyroid autoimmunity (TAI). This study aimed to investigate whether low VitD2 or VitD3 potentially contributed to the development of TAI in euthyroid male patients, which had not been reported before.

Methods: A total of 2882 euthyroid male petroleum workers were recruited from those participants in the healthcare program at the second affiliated hospital of Dalian Medical University in 2021, whose serum VitD levels, thyroid functions, and autoantibody titers were all examined at the same time.

Residual Al Adatoms Driven Epitaxy of AlGaN QWs for High-Performance UV LEDs.

AlGaN-based ultraviolet (UV) light-emitting diodes (LEDs) experience a notable reduction in efficiency within the 280-330 nm wavelength range, known as the "UVB gap". Given the extensive applications of UV LEDs in this wavelength range, it is imperative to bridge this efficiency gap. In this study, a strategy facilitated by the presence of residual Al adatoms is introduced to simultaneously improve the integration of Ga-adatoms and the migration of Al/Ga-adatoms during the growth of low-Al-composition AlGaN quantum wells (QWs) even at high temperatures comparable to those used for high-Al-composition AlGaN quantum barriers.

Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression.

Aims: Endometriosis development is associated with peritoneal immune microenvironment abnormality; however, the specific mechanism is uncertain. We aimed to investigate the effects and underlying mechanisms of uterine cavity-derived exosomes on macrophage polarization and endometriosis progression.

Materials And Methods: Uterine cavity-derived exosomes, miR-210-3p inhibitor or siATP5D were used to treat macrophages.

Unveiling the link: anti-protein disulfide isomerase A3 autoantibody expression and polycystic ovary syndrome risk in euthyroid autoimmune thyroiditis women.

Background: Polycystic ovary syndrome (PCOS) is a common complication of autoimmune thyroiditis (AIT) in women, but the underlying mechanism remains unclear. Protein disulfide isomerase A3 (PDIA3) is a ubiquitous protein. We have reported that PDIA3 autoantibody (PDIA3Ab) production results from autoimmune responses against thyrocytes, resulting in its high expression in euthyroid AIT patients.

Serum metabolite profiles of thyroid autoimmunity patients in early pregnancy.

Background: Research on serum metabolite profiles in thyroid autoimmunity (TAI) patients during early pregnancy is currently limited.

Aim & Methods: The current study aimed to identify differential serum metabolites and assess the relationship between pregnancy outcomes and metabolic abnormalities in individuals with TAI. This research included 26 pregnant women with TAI and 30 healthy controls (HC).

Effect of low-purine diet on the serum uric acid of gout patients in different clinical subtypes: a prospective cohort study.

Background: The pathogenic causes of primary gout include urate overproduction and/or renal or extra-renal urate underexcretion. The aim of this study was to evaluate the association of gout subtypes with the response to low-purine diet (LPD).

Methods: This is a single-center prospective clinical study.

Cholinergic nucleus degeneration and its association with gait impairment in Parkinson's disease.

Background: The contribution of cholinergic degeneration to gait disturbance in Parkinson's disease (PD) is increasingly recognized, yet its relationship with dopaminergic-resistant gait parameters has been poorly investigated. We investigated the association between comprehensive gait parameters and cholinergic nucleus degeneration in PD.

Methods: This cross-sectional study enrolled 84 PD patients and 69 controls.

Production of Coal Fines in Deep Coal Seam via Morphologic, Flow-Channel, Mineral Analyses: Evidence from Coalbed Methane Wells in the Qinshui Basin.

During the development of deep coalbed methane (CBM), the production of coal fines is common and suppresses the yield of CBM. This work takes the deep CBM wells in the Qinshui Basin as a case study, and the output, composition, morphology, and sources of coal fines were investigated through scanning electron microscopy, X-ray diffraction, proximate analysis, and particle size measurement including image analysis, laser diffraction, and dynamic light scattering. The results indicate that, in comparison with shallow CBM wells, deep wells produce a greater quantity of coal fines which are darker in color and have smaller particle sizes, with the majority being less than 10 μm.

The Difference between Stress Deformation and Adsorption Deformation of Coal Reservoirs and Its Role in Permeability Prediction.

The key to the variation in permeability within coal reservoirs lies in the stress-induced deformation and desorption-induced deformation during the coalbed methane (CBM) production. The differences in sample scale and measurement methods between stress-induced deformation and desorption-induced deformation significantly affect the accuracy of permeability measurements. Therefore, in order to elucidate the relationship between stress-induced deformation and adsorption-induced deformation, as well as the influencing factors, and to assess the accuracy of permeability evolution prediction, this study conducted a series of parallel experiments, including compression deformation experiments under stress loading (stress-induced deformation), methane adsorption-induced deformation experiments (adsorption-induced deformation), μCT scanning, and overburden permeability measurements.

Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides.

Introduction: Antimicrobial peptides (AMPs) are valuable alternatives to traditional antibiotics, possess a variety of potent biological activities and exhibit immunomodulatory effects that alleviate difficult-to-treat infections. Clarifying the structure-activity relationships of AMPs can direct the synthesis of desirable peptide therapeutics.

Objectives: In this study, the lipopolysaccharide-binding domain (LBD) was identified through machine learning-guided directed evolution, which acts as a functional domain of the anti-lipopolysaccharide factor family of AMPs identified from Marsupenaeus japonicus.

Experimental research on compressive strength deterioration of coal seam floor sandstone under the action of acidic mine drainage.

In sulphur-coal symbiotic coal seams, after the mining of sulphide iron ore, when the coal resources are mined, the mine water accumulated in the roadway mining area will have a certain impact on the stability of the surrounding rock of the coal seam roadway. Taking the floor sandstone of sulfur coal symbiotic coal seam as the research object, the roof fissure water with pH values of 7.48, 4.

Corrigendum: Single- and dual-task gait performance and their diagnostic value in early-stage Parkinson's disease.

[This corrects the article DOI: 10.3389/fneur.2022.

Prevalence and predictors of help-seeking behavior among post-partum women with urinary incontinence in China and Indonesia: A cross-sectional survey based on Andersen Help-Seeking Model.

Introduction: Urinary incontinence (UI) is a prevalent condition among post-partum women, and it can significantly affect their physical and psychosocial well-being. Therefore, it's crucial for post-partum women to discuss any UI symptoms they may be experiencing with their healthcare provider and seek appropriate treatment.

Purpose: To investigate what leads post-partum women with UI to seek help in China and Indonesia based on the Andersen Help-Seeking Model.

Prevalence and Influencing Factors of Help-Seeking Behavior Among Women with Urinary Incontinence: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis aimed to investigate the mean (weighted) prevalence of help-seeking behavior among women with urinary incontinence (UI) in relevant subgroups and the related influencing factors. Six English and four Chinese databases were systematically searched between 1996 and July 10, 2022. Two researchers independently screened the literature, extracted data, and evaluated the quality of the included studies.

Mother-child dyadic responses to children facing challenges: An examination across ethnicities.

The current study (a) examined ethnic differences in mothers' and children's responses to children's performance in a challenging task, (b) tested the associations among children's desire for assistance, maternal control, and children's emotional responses to the challenge, and (c) explored whether these associations held across three ethnicities-Asian Americans (AA), Latinx Americans (LA), and European Americans (EA). Results showed that children's emotional arousal significantly increased and emotional valence became significantly less positive over the course of children experiencing repeated challenges in front of their mothers. In terms of ethnic differences, LA mothers exhibited more control than EA mothers, but LA children responded less negatively to the challenging task than EA children.