Behçet's disease (BD) is a multisystem inflammatory condition that rarely affects the nasal mucosa. We report the case of a 25-year-old man presenting with prolonged fever, bilateral rhinalgia, and nasal obstruction, who was subsequently diagnosed with nasal ulcers associated with BD. These ulcers resolved along with the systemic symptoms following treatment with colchicine, apremilast, and prednisolone.
View Article and Find Full Text PDFEnsuring the stability of electrocatalysts is paramount to the success of electrochemical energy conversion devices. Degradation is a fundamental process involving the release of positively charged metal ions into the electric double layer (EDL) and their subsequent diffusion into the bulk electrolyte. However, despite its vital importance in achieving prolonged electrocatalysis, the underlying causality of catalyst dissolution with the EDL structure remains largely unknown.
View Article and Find Full Text PDFWe herein report the first case of dyspnea with hemidiaphragm elevation in a 68-year-old woman with active giant cell arteritis (GCA), including successful treatment. Contrast-enhanced computed tomography showed a reduced density of the left ophthalmic artery and the left superficial temporal artery with increased soft tissue compared to the other side, indicating that the GCA had flared up and suggesting that the hemidiaphragm elevation might be caused by vasculitis-associated ischemia of the right phrenic nerve. Hemidiaphragm paralysis due to vasculitis-associated ischemia in patients with GCA needs to be distinguished from local infection, tumors, and hepatomegaly, which are the major causes of hemidiaphragm elevation.
View Article and Find Full Text PDFMod Rheumatol Case Rep
January 2025
A woman in her 60s presented with erythema on both elbows, dyspnea on exertion, discomfort, and swelling of the left upper extremity, followed by swelling and myalgia of the right upper and lower extremities. She was diagnosed with anti-transcriptional intermediary factor 1-γ antibody-positive dermatomyositis with interstitial pneumonia. The initial screening tests for malignant diseases including contrast-enhanced computed tomography, upper and lower endoscopy, and gynecological examination did not reveal any obvious abnormalities.
View Article and Find Full Text PDFBackground: Patient trust plays a central role in the patient-physician relationship. This study aimed to determine whether the number of outpatient visits with a covering rheumatologist is associated with patient trust in their usual rheumatologist.
Methods: Japanese adults with systemic lupus erythematosus (SLE) who met the 1997 revised classification criteria of the American College of Rheumatology and had outpatient visits with a covering rheumatologist in the past year were included.
Lithium (Li) metal negative electrodes have attracted wide attention for high-energy-density batteries. However, their low coulombic efficiency (CE) due to parasitic electrolyte reduction has been an alarming concern. Concentrated electrolytes are one of the promising concepts that can stabilize the Li metal/electrolyte interface, thus increasing the CE; however, its mechanism has remained controversial.
View Article and Find Full Text PDFJ Colloid Interface Sci
August 2024
Hypothesis: The formation of soft colloidal crystals, which are nonclose-packed ordered arrays of colloidal particles suspended in a solvent, is dictated by a single physical factor that yields a fixed threshold at order-disorder boundaries for different experimental conditions such as ion concentration, solvent type, and particle size. Identifying the determinant factor and its threshold value should enable the prediction of the critical concentrations of colloidal particles to form soft colloidal crystals.
Experiments: Soft colloidal crystals were fabricated using a series of monohydric alcohols as dispersion media and reflectance spectra were measured to locate order-disorder boundaries.
Understanding the effect of noncovalent interactions of intermediates at the polarized catalyst-electrolyte interface on water oxidation kinetics is key for designing more active and stable electrocatalysts. Here, we combine optical spectroscopy, X-ray absorption spectroscopy (XAS), and surface-enhanced infrared absorption spectroscopy (SEIRAS) to probe the effect of noncovalent interactions on the oxygen evolution reaction (OER) activity of IrO in acidic and alkaline electrolytes. Our results suggest that the active species for the OER (Ir-*O) binds much stronger in alkaline compared with acid at low coverage, while the repulsive interactions between these species are higher in alkaline electrolytes.
View Article and Find Full Text PDFBMC Musculoskelet Disord
February 2024
Li-mediated ammonia synthesis is, thus far, the only electrochemical method for heterogeneous decentralized ammonia production. The unique selectivity of the solid electrode provides an alternative to one of the largest heterogeneous thermal catalytic processes. However, it is burdened with intrinsic energy losses, operating at a Li plating potential.
View Article and Find Full Text PDFMod Rheumatol Case Rep
December 2023
We present a case of microhematuria, proteinuria and hypocomplementemia which developed in a 55-year-old female who was being treated with an infliximab biosimilar for rheumatoid arthritis. Renal biopsy showed lupus nephritis (ISN/RPS classification class IV + V). Treatment with the infliximab biosimilar was discontinued, and treatment with prednisolone, hydroxychloroquine and abatacept was started, resulting in clinical remission of lupus nephritis and RA.
View Article and Find Full Text PDFNovel electrolyte systems are required to further improve the performance and ensure the safety of lithium-ion batteries. Lithium-monochelated borates with trifluoromethylated ligands are used as electrolytes for lithium-ion batteries (LIBs) with a lithium bis(oxalato)borate (LiBOB) additive. The capacity decay and extremely high resistance after the cycle test at 60 °C are dramatically suppressed by the addition of LiBOB.
View Article and Find Full Text PDFA 34-year-old woman with pulmonary arterial hypertension (PAH) was admitted to the hospital. She had been diagnosed with PAH three years earlier and treated with triple vasodilator therapy. She was positive for anti-U ribonucleoprotein antibodies but did not show any other symptoms associated with autoimmune diseases.
View Article and Find Full Text PDFObjectives: There is a high prevalence of burnout among rheumatologists. Grit, which is defined as possessing perseverance and a passion to achieve long-term goals, is predictive of success in many professions; however, whether grit is associated with burnout remains unclear, especially among academic rheumatologists, who have multiple simultaneous responsibilities. Thus, the purpose of this study was to examine the associations between grit and self-reported burnout components-professional efficacy, exhaustion, and cynicism-in academic rheumatologists.
View Article and Find Full Text PDFCardiovascular disease in patients with systemic lupus erythematosus (SLE) remains one of the most common causes of death and is caused by several factors, including both traditional and disease-specific risk factors. We aimed to systematically appraise the evidence of cardiovascular disease risk factors focusing on the SLE population. The protocol for this umbrella review is registered in PROSPERO (registration no.
View Article and Find Full Text PDFACS Energy Lett
February 2023
The lithium-mediated system catalyzes nitrogen to ammonia under ambient conditions. Herein we discover that trace amount of water as an electrolyte additive-in contrast to prior reports from the literature-can effect a dramatic improvement in the Faradaic selectivity of N reduction to NH. We report that an optimal water concentration of 35.
View Article and Find Full Text PDFNa metal is a promising anode material for the preparation of next-generation high-energy-density sodium-ion batteries; however, the high reactivity of Na metal severely limits the choice of electrolyte. In addition, rapid charge-discharge battery systems require electrolytes with high Na-ion transport properties. Herein, we demonstrate a stable and high-rate sodium-metal battery enabled by a nonaqueous polyelectrolyte solution composed of a weakly coordinating polyanion-type Na salt, poly[(4-styrenesulfonyl)-(trifluoromethanesulfonyl)imide] (poly(NaSTFSI)) copolymerized with butyl acrylate, in a propylene carbonate solution.
View Article and Find Full Text PDFObjective: Fatigue is one of the most common complaints and is a potentially modifiable issue in systemic lupus erythematosus (SLE). Studies suggest that alcohol consumption has a protective effect against the development of SLE; however, an association between alcohol consumption and fatigue in patients with SLE has not been studied. Here, we assessed whether alcohol consumption was associated with fatigue using lupus patient-reported outcomes (LupusPRO).
View Article and Find Full Text PDFRheumatology (Oxford)
June 2023
Objectives: Although personality characteristics of patients with SLE affect their disease activity and damage, it is unclear whether those of attending physicians affect the outcomes of patients with SLE. Grit is a personality trait for achieving long-term goals that may influence the decision-making for continuing treatment plans for patients. We aimed to evaluate the relationship between the grit of attending physicians and achievement of treatment goals in patients with SLE.
View Article and Find Full Text PDFObjective: It is still unclear how glucocorticoids (GCs) affect the long-term clinical course of patients with SLE. The objective of this study is to explore the factors associated with GC-free treatment status.
Methods: Using data from the lupus registry of nationwide institutions, GC dose at registration was compared between short, middle and long disease durations of <5, 5-20 and ≥20 years, respectively.
The design guidelines of polymer structure to effectively promote lithium-ion conduction within the polymer electrolytes (PEs) are crucial for its practical use. In this study, the electrolyte properties of a simple polyether having alkyl side chains with varied lengths (-(CH)-H, = 1, 2, 4, 6, 8, and 12) were compared and established a valid design strategy based on the properties of the alkyl side chain. Various spectro-electrochemical measurements successfully connected the electrolyte properties and the alkyl side chain length.
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