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Article Abstract
Objective: It is still unclear how glucocorticoids (GCs) affect the long-term clinical course of patients with SLE. The objective of this study is to explore the factors associated with GC-free treatment status.
Methods: Using data from the lupus registry of nationwide institutions, GC dose at registration was compared between short, middle and long disease durations of <5, 5-20 and ≥20 years, respectively. After excluding patients who never used GC, we evaluated the relationship between GC-free status and chronic damage using Systemic Lupus International Collaborating Clinics Damage Index.
Results: GC doses at enrolment of the 1019 patients were as follows: GC-free in 101 (10%); 0
Conclusion: Even in the patients with long disease duration, one-point GC-free treatment status might be related to no chronic damage accrual.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516281 | PMC |
| http://dx.doi.org/10.1136/lupus-2022-000772 | DOI Listing |
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