Publications by authors named "Yingxin Gao"

Water pollutants, in particular emerging contaminants, pose severe risks to aquatic ecosystems and public health due to their high persistence and bioaccumulation potential. While advanced oxidation processes (AOPs) offer sustainable solutions for pollutant degradation, plasma-based AOPs often suffer from low energy efficiency and slow mass transfer of active species. Here we report a spatially-confined plasma AOP, generated in situ by electrical discharge within microchannel during bubble formation.

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Ischemia-reperfusion injury (IRI) is the leading cause of hepatic graft dysfunction, resulting from hepatocyte damage. Nevertheless, given the few specialized therapeutics available in hepatic IRI, additional mechanistic insights into hepatocyte damage are required. Here, the protein solute carrier family 39 member 14 (SLC39A14) is identified as a pro-ferroptosis target in hepatocytes of human liver allografts through single-cell RNA sequencing analysis.

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Article Synopsis
  • This study focuses on improving polyp detection during colonoscopy by developing a new model that enhances segmentation accuracy using a combination of CNNs and transformers.
  • The proposed architecture includes a multi-scale nested UNet structure designed to effectively learn local features while also incorporating long-range dependencies for better context understanding.
  • Results from testing on various datasets indicate that the new model significantly outperforms existing methods, achieving high accuracy in polyp segmentation across different sizes, suggesting strong potential for clinical applications.
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Acute lung injury (ALI) is one of the most serious complications of sepsis, characterized by high morbidity and mortality rates. Ferroptosis has recently been reported to play an essential role in sepsis-induced ALI. Excessive neutrophil extracellular traps (NETs) formation induces exacerbated inflammation and is crucial to the development of ALI.

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Objectives: To evaluate the efficacy of miniprobe endoscopic ultrasonography for the diagnosis and adjuvant treatment of patients with colorectal submucosal lesions.

Methods: The retrospective study was conducted at the Beijing Chao-Yang Hospital, Capital Medical University, China, and comprised data from January 1, 2016, to July 31, 2021, related to patients of either gender with colorectal submucosal lesions who underwent miniprobe endoscopic ultrasonography. The findings were compared with biopsy specimens and clinical diagnoses.

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Background: Postinduction hypotension caused by propofol remains a non-negligible problem for anesthesiologists, and is especially severe in chronic hypertensive patients with long-term vasoconstriction and decreased vascular elasticity. The functional change in gap junctions composed of Cx43 (Cx43-GJs) is reported as the biological basis of synchronized contraction or relaxation of blood vessels. Thus, we investigated the role of Cx43-GJs in propofol-induced dramatic blood pressure fluctuations in chronic hypertensive patients, and their internal mechanisms.

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Activated carbon is widely used to remove effluent organic matter (EfOM) from bio-treated coking wastewater. However, the critical carbon properties affecting adsorption performance are still unclear. Nine commercial powdered activated carbons (PACs) with different pore structures, surface functional groups, and surface charges were used to adsorb EfOM from bio-treated coking wastewater, which was fractionated according to their molecular weight (MW) and hydrophobicity.

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The protein Talin1 encoded by the TLN1 gene is a focal adhesion-related protein that binds to various cytoskeletal proteins and plays an important role in cell adhesion and movement. Recent studies have shown that it is overexpressed in prostate cancer, liver cancer, and oral squamous cell carcinoma, and is closely related to tumor progression and metastasis. This study integrated bioinformatics and functional analysis to reveal the prognosis and potential functions of TLN1 in AML.

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While abundant volatile compounds (VOCs) have been identified in coking wastewater, the structures and occurrence of non-volatile organic compounds (non-VOCs) have remained unknown. In this study, 3966 non-VOCs belonging to 24 groups were tentatively identified for the first time in wastewater from four biological coking wastewater treatment systems in northern China using a non-target screening technique. A total of 227 compounds with CHNO, CHO, CHOS, and CHNOS elemental compositions were assigned with level 2 identification confidence, and 19 of them were confirmed with authentic standards, with 9-methyl-9H-carbazole-3-carbaldehyde (1706.

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In this study, the distribution profiles, emission characteristics, and health risks associated with 43 volatile and semi-volatile organic compounds, including 15 phenols, 18 polycyclic aromatic hydrocarbons (PAHs), 6 BTEX, and 4 other compounds, were determined in the wastewater treatment plant (WWTP) of a coking factory (plant C) and the succeeding final WWTP (central WWTP). Total phenols with a concentration of 361,000 μg L were the predominant compounds in the influent wastewater of plant C, whereas PAHs were the major compounds in the final effluents of both coking WWTPs (84.4 μg L and 30.

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It is a challenging environmental issue to develop a cost-efficient approach for the removal of low-concentration refractory organics in industrial wastewater. In this study, the Fenton-coagulation process was utilised to remove the organics from the industrial effluent. The operational conditions of the Fenton-coagulation process were optimised, and then, the molecular weight (MW) and resin fraction distribution of dissolved organic matter (DOM) were investigated before and after the Fenton-coagulation process.

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Efficient removal of the non-biodegradable organics from the biological effluent of industrial wastewater is becoming more and more important with the increasing demand for stringent discharge regulation. In this study, a synchronized oxidation-adsorption (SOA) technology was proposed for the removal of hardly biodegradable COD (hard COD) from the biological effluent of coking wastewater, and its performance was verified in a full-scale coking industrial park wastewater treatment plant (Q = 5,000 m/d). The SOA was performed by coupling oxidation by hydroxyl radical (molar ratio of Fe to HO of 1:1 and pH = 5.

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Background: The Asia-Pacific Colorectal Screening (APCS) score is effective to screen high-risk groups of advanced colorectal neoplasia (ACN) patients but needs revising and can be combined with the fecal immunochemical test (FIT). This paper aimed to improve the APCS score and evaluate its use with the FIT in stratifying the risk of ACN.

Methods: This prospective and multicenter study enrolled 955 and 1201 asymptomatic Chinese participants to form the derivation and validation set, respectively.

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Fenton (Fe + HO) reagents acting to remove organic pollutants possess dual functions, including the oxidation by hydroxyl radicals and the coagulation of Fe(III). Previous papers have extensively studied the oxidation reactions by hydroxyl radicals, however, the coagulation role of Fenton for benzoic acid (BA) removal is not clear. Comparing three coagulation systems, it was found that Fenton coagulation possesses a significant advantage for the removal of BA.

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This study focused on investigating reactor performance, simultaneous methanogeneis and denitrifiction (SMD) process for treatment of a sulfate plus organic sulfur - rich 3,4,5-Triethoxybenzaldehyde (TMBA) manufacturing wastewater with variable COD/TSO (total sulfate) ratio by micro-electric field- zero-valent-iron (ZVI) UASB for 390 days. The initial COD/TSO was set as 1.42, 0.

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In this study, an extended Fenton process was used to improve biodegradability of the waste drilling mud containing bio-refractory polymers. Variation of biodegradability and organics with different molecular weights with the oxidation time were investigated during the Fenton oxidation process. Although the residual total organic carbon (TOC) arrived at a stable level soon after oxidation reaction, organics with the lower molecular weight increased and its biodegradability was improved significantly in the extended oxidation process, which originated from decomposition of residual HO catalyzed by transformation of the Fe/Fe and organoradicals.

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Due to the severe restrictions imposed by legislative frameworks, the removal of polyacrylamide (PAM) rapidly and effectively from produced wastewater in offshore oilfields before discharge is becoming an urgent challenge. In this study, a novel advanced oxidation process based on plasma operated in the gas-liquid interface was used to rapidly decompose PAM, and multiple methods including viscometry, flow field-flow fractionation multi-angle light scattering, UV-visible spectroscopy, and attenuated total reflectance-Fourier transform infrared spectroscopy were used to characterize the changes of PAM. Under a discharge voltage of 25 kV and pH 7.

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It is of great significance to know the fate of the polymers and surfactants used for enhanced oil recovery (EOR) in oil reservoirs at a relatively high temperature/pressure. In this paper, the changes of the properties of a polymer (partially hydrolyzed polyacrylamide, HPAM) and a surfactant (petroleum sulfonate, PS) were investigated under simulated oil reservoir conditions (a temperature of 45, 60 or 75 °C and a pressure of 10, 15 or 20 MPa). The impacts of the property changes to emulsion stability were also highlighted.

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Colorectal cancer (CRC) is the third most common cancer worldwide. Its incidence is still increasing, and the mortality rate is high. New therapeutic and prognostic strategies are urgently needed.

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This study aimed to evaluate the feasibility of hyperthermophilic anaerobic digestion at 70 °C in the pretreatment of spiramycin fermentation residue. By feeding municipal excess sludge under a solid retention time of 5 days, the hyperthermophilic digester was successfully started up within 3 days from mesophilic digestion by a one-step temperature increase from 35 to 70 °C. MiSeq sequencing showed the fast establishment of thermophilic fermenting bacterial communities in 3 days immediately after the temperature increase, with increases in abundance of Coprothermobacter, Spirochaetaceae_uncultured and Fervidobacterium from <0.

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Sludge bulking caused by the overgrowth of filamentous bacteria, especially Microthrix parvicella, has been observed in WWTPs worldwide during low-temperature periods. In this study, the impacts of sludge load on the in situ growth of M. parvicella and sludge settleability were first evaluated at 15 °C over a period of 500 d using a bench-scale anaerobic-anoxic-aerobic reactor fed with raw sewage from a full-scale WWTP.

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Ultrasonic technology is a promising tool for washing oily sludge to remove oil, however, little information has been provided on the pilot scale application of ultrasonic washing. In this study, the ultrasonic conditions were optimized based on the pilot trial of the effects of ultrasonic properties on oil removal from oily sludge. An ultrasonic power of 0.

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Nitrogenous heterocyclic compounds are key pollutants in coking wastewater; however, the functional potential of microbial communities for biodegradation of such contaminants during biological treatment is still elusive. Herein, a high throughput functional gene array (GeoChip 5.0) in combination with Illumina HiSeq2500 sequencing was used to compare and characterize the microbial community functional structure in a long run (500days) bench scale bioreactor treating coking wastewater, with a control system treating synthetic wastewater.

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To recover oil from crude oil containing sludge is still a research hot topic from the view of sustainability, in which ultrasonic has been proven to be an efficient and environment friendly technique. However, the effect of sludge characteristic on ultrasonic-assisted oil recovery efficiency is little known. In this study, the analysis of variance (ANOVA) was conducted based on six types of crude oily sludge with hydrophilicity and lipophilicity separately and five different ultrasonic operation factors (ultrasonic power (A), frequency (B), time (C), initial temperature (D) and pH (E)).

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