GATA transcription factors in bivalves: Genomic diversity, evolutionary conservation, and roles in environmental adaptation.

The GATA transcription factors, characterized by conserved zinc-finger domains, play crucial roles in regulating gene expression during development and environmental adaptation in animals. However, their evolutionary patterns and functional characteristics in bivalves remain poorly understood. In this study, we identified 118 GATA genes across 32 bivalve species uncovering the conservation and diversity of this gene family during evolution.

Identification and analysis of caspase genes in bivalves and their expression patterns in noble scallop Chlamys nobilis under low-temperature stress.

Apoptosis is essential for a variety of biological processes, such as tissue homeostasis, organism development, and responses to environmental stresses. As central regulators of apoptosis, cysteine-aspartic proteases (caspases) orchestrate the intermediate and execution phases. However, the roles of the caspase gene family in bivalves is still unknown.

Lysozyme genes in bivalves: Evolutionary insights and functional roles in host defense against Vibrio infections.

Bivalves are economically and ecologically significant species that are constantly exposed to environmental stressors and pathogens, particularly Vibrio species, which pose persistent threats to bivalve aquaculture. Lysozymes, key immune effectors, play crucial roles in host defense against microbial invasion. However, systematic studies on bivalve lysozymes across multiple species remain limited.

Genome-wide identification of 14-3-3 gene family and their expression profiles under low temperature stress in noble scallop Chlamys nobilis.

The 14-3-3 family genes, highly conserved regulatory factors in eukaryotes, play critical roles in cellular regulation and stress adaptation. Despite extensive research in vertebrates and some aquatic species, the functional roles of 14-3-3 genes in bivalves remain underexplored. In this study, we identified and characterized five 14-3-3 genes (Cn14-3-3a to Cn14-3-3e) in the noble scallop Chlamys nobilis.

Is Shigella an under-recognized pathogen? A case of pyogenic cervical spondylitis caused by and infection.

typically causes gastrointestinal infections, and extra-intestinal manifestations are rare. We report the first known case of pyogenic cervical spondylitis co-infected with and , highlighting the diagnostic challenges and clinical implications. A 53-year-old woman presented with neck pain for one month.

Secondary hand infection with and in a patient with Behcet's disease: a case report.

We report the first case of a woman with Behcet's disease (BD) with multiple hand ulcers secondary to coninfection by and resulting in necrotizing fasciitis. She had a long history of BD including long courses of prednisone and immunosuppressants. The patient was hospitalized for multiple superficial ulcers, swelling, and infection of the hands.

Acute myocardial infarction as the first sign of infective endocarditis: a case report.

Infective endocarditis is a bacterial or fungal infection of the heart valves or endocardial surface, and it frequently forms vegetation and can lead to systemic embolism. Dislodged vegetation rarely results in coronary artery embolism (CAE) and subsequent acute myocardial infarction. A 43-year-old male patient was emergently brought to our hospital for suspected acute myocardial infarction.

Factors associated with emergency services use in Taiwanese advanced cancer patients receiving palliative home care services during out-of-hours periods: a retrospective medical record study.

Background: For patients receiving palliative home care, the need to visit the emergency department is considered to be an indicator of poor quality care. The situation can be particularly distressing when it occurs outside of normal hours of palliative home care service. The aim of this study was to investigate the factors for emergency department use during out-of-hours periods of palliative home care service among advanced cancer patients in Taiwan.

A Possible Link Between Rheumatoid Arthritis and Periodontitis: A Systematic Review and Meta-analysis.

Previous studies have shown that patients with rheumatoid arthritis (RA) have a higher susceptibility to periodontitis, but the results of individual studies remain controversial. The aim of the present meta-analysis was to comprehensively evaluate the association between RA and periodontitis. A systematic literature search was conducted in PubMed and EMBASE.

Circulating microRNA expression is associated with genetic subtype and survival of multiple myeloma.

Circulating microRNAs (miRNAs) have shown potential as non-invasive prognostic biomarkers in cancer. Here, we investigated whether miRNAs present in the plasma of multiple myeloma (MM) patients have prognostic utility. We evaluated global miRNA expression profiles in the plasma of 12 multiple myeloma patients and 8 healthy controls using TaqMan Low-Density Arrays.

Continuous treatment with recombinant Mycobacterium tuberculosis CFP-10-ESAT-6 protein activated human monocyte while deactivated LPS-stimulated macrophage.

Influence of the recombinant culture filtered protein 10 (CFP-10) and early-secreted antigenic target 6kDa protein (ESAT-6) (r-CFP-10-ESAT-6, rCE) of Mycobacterium tuberculosis (Mtb) on human monocyte and macrophage activation was investigated using human monocyte, monocyte like THP-1 cell line and monocyte derived macrophage (MDM). rCE solely enhanced TNF-alpha release from human monocytes and THP-1 cells in a dose- and time-dependent manner. rCE enhanced expression of CD80 and CD40, it also synergized with IFN-gamma in induction of TNF-alpha production and HLA-DR expression.