Altered resting-state brain entropy by repetitive transcranial magnetic stimulation across the human cortex.

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique used to treat neuropsychiatric disorders. Despite its efficacy, its neuro-mechanisms remain unclear. Brain entropy (BEN), a measure of the irregularity and complexity of brain activity, has been shown to reflect the effects of high-frequency rTMS (HF-rTMS).

Detection of X-ray emission from a bright long-period radio transient.

Recently, a class of long-period radio transients (LPTs) has been discovered, exhibiting emission thousands of times longer than radio pulsars. These findings, enabled by advances in wide-field radio surveys, challenge existing models of rotationally powered pulsars. Proposed models include highly magnetized neutron stars, white-dwarf pulsars and white-dwarf binary systems with low-mass companions.

The effects of intermittent theta burst stimulation (iTBS) on resting-state brain entropy (BEN).

Intermittent theta burst stimulation (iTBS), a novel protocol within repetitive transcranial magnetic stimulation (rTMS), has shown superior therapeutic effects for depression compared to conventional high-frequency rTMS (HF-rTMS). However, the neural mechanisms underlying iTBS remain poorly understood. Brain entropy (BEN), a measure of the irregularity of brain activity, has recently emerged as a promising marker for regional brain function and has demonstrated sensitivity to depression and HF-rTMS.

Single-Wavelength Laminar Optical Tomography for In Vivo Microvascular Three-Dimensional Imaging.

Laminar Optical Tomography (LOT) is a promising non-invasive technique for three-dimensional imaging of complex biological structures, combining high resolution and deep penetration. In this study, a LOT system was assembled using a 520nm continuous-wave laser, exploiting the contrast mechanism provided by the unique optical absorption coefficient of hemoglobin at this wavelength for microvascular imaging. The system utilizes raster scanning to illuminate the target tissue's surface, capturing backscattered light intensity with a multi-channel Photomultiplier Tubes.

Modulation of Ultrasonic Stimulation Parameters towards Evoking Fine Tactile Sensations.

An increasing number of recent studies prove that the low-intensity focused ultrasound stimulation (LIFUS) is a promising neuromodulation technique. Its feasibility of eliciting multiple fine tactile sensations, as well as the modulatory effect of ultrasonic stimulation parameters have not been investigated by far. Therefore, in this work, we enrolled eight healthy volunteers to participate into two sets of psychophysical experiment, wherein the ultrasonic stimuli were delivered onto their index fingertips under varying pulse repetition frequency (PRF) and acoustic intensity (AI).

Low-Intensity Focused Ultrasound Stimulation on Fingertip Can Evoke Fine Tactile Sensations and Different Local Hemodynamic Responses.

Low-intensity focused ultrasound stimulation (LIFUS) has been proved effective in eliciting vibrotactile in addition to warm, cold and nociceptive pain when applied to human peripheral endings. However, if it can evoke fine tactile sensations has been rarely investigated by far despite the importance of fine tactile feedback in motor control. To explore this issue, 14 healthy volunteers were recruited in this study.

Function-Specific Localization in the Supplementary Motor Area: A Potential Effective Target for Tourette Syndrome.

Aims: Repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) may treat Tourette's syndrome (TS) by modulating the function of the globus pallidus internus (GPi) via the cortico-striato-thalamo-cortical circuit.

Methods: We conducted a randomized longitudinal study to examine circuit functionality and clinical efficacy. The GPi was identified as an "effective region" for TS treatment.

Integrating spatial clustering and multi-source geospatial data for comprehensive geological hazard modeling in Hunan Province.

This study presents an integrated framework that combines spatial clustering techniques and multi-source geospatial data to comprehensively assess and understand geological hazards in Hunan Province, China. The research integrates self-organizing map (SOM) and geo-self-organizing map (Geo-SOM) to explore the relationships between environmental factors and the occurrence of various geological hazards, including landslides, slope failures, collapses, ground subsidence, and debris flows. The key findings reveal that annual average precipitation (Pre), profile curvature (Pro_cur), and slope (Slo) are the primary factors influencing the composite geological hazard index (GI) across the province.

Revealing the off-flavors in hydro-distilled essential oils of sweet orange (Citrus sinensis) by flavoromics strategy and computational simulation.

Citrus essential oils (EOs) are renowned for their aroma, but thermal extraction methods can introduce undesirable cooking and pungent odors. The specific compounds responsible for these off-flavors and their perception mechanisms remain unclear. This study investigated the flavor differences between cold pressing (CP) and hydro-distilled (HD) extracted essential oils from sweet oranges (SEOs) using flavoromics strategy.

Black shale high geological background potential toxic elements(PTEs) in middle reaches of the Yangtze River tributary basin water environment, China: Distribution, pollution sources, and risk assessment.

As a typical high geological background area in the middle reaches of the Yangtze River tributary basin in China, the Loushao Basin in Hunan is covered with high mineral black shale, with an average element value 4.76-8.97 times higher than the world average rock level.

Black shale bedrock control of soil heavy metal typical high geological background in China Loushao Basin: Pollution characteristics, source and Influence assessment based on spatial analysis.

During the process of black shale weathering, multiple heavy metal elements are concentrated in the soil, causing pollution. This study selected soil and black shale bedrock samples from high geological background areas to investigate the control of heavy metal element pollution by bedrock using spatial analysis. The research results indicate that the heavy metal content in black shale bedrock is extremely high, ranging from 2.

Toxic element characterization against a typical high geology background: Pollution enrichment, source tracking, spatial distribution, and ecological risk assessment.

The geological environment determines the initial content of various elements in soil, while the late input of toxic elements produced through weathering and leaching is a persistent threat to food security and human health. In this study, we selected the Lou Shao Basin, a black rock system background, and combined geostatistical analysis and multivariate statistics to quantify the specific contribution of weathering of the black rock system, and to analyze the source traces, spatial distributions, and ecological risks of the soil toxicity of elements. The results show that the soils in the study area are acidic, which is related to the weathering of sulfides in the black rock system.

Online and offline effects of parietal 10 Hz repetitive transcranial magnetic stimulation on working memory in healthy controls.

Parietal alpha activity shows a specific pattern of phasic changes during working memory. It decreases during the encoding and recall phases but increases during the maintenance phase. This study tested whether online rTMS delivered to the parietal cortex during the maintenance phase of a working memory task would increase alpha activity and hence improve working memory.

Potential toxic heavy metals in village rainwater runoff of antimony mining area, China: Distribution, pollution sources, and risk assessment.

The potential toxic heavy metal runoff from antimony mining areas poses a serious threat to the water environment and the health of residents in the village. The study found that the average concentrations of As, Sb, Cr, Pb, and Cd in the runoff were 0.1237, 0.

A preliminary study of multispectral Cherenkov imaging and a Fricke-xylenol orange gel film (MCIFF) for online, absolute dose measurement.

Background: Cherenkov luminescence imaging has shown potential for relative dose distribution and field verification in radiation therapy. However, to date, limited research utilizing Cherenkov luminescence for absolute dose calibration has been conducted owing to uncertainties arising from camera positioning and tissue surface optical properties.

Purpose: This paper introduces a novel approach to multispectral Cherenkov luminescence imaging combined with Fricke-xylenol orange gel (FXG) film, termed MCIFF, which can enable online full-field absolute dose measurement.

Adsorption of Sb(III) and Pb(II) in wastewater by magnetic γ-FeO-loaded sludge biochar: Performance and mechanisms.

Magnetically modified carbon-based adsorbent (BC@γ-FeO) was prepared through facile route using activated sludge biomass and evaluated for the simultaneous removal of Sb(III) and Pb(II). BC@γ-FeO exhibited outstanding Sb(III) and Pb(II) adsorption capacity when 200 mg of adsorbent was employed at pH 5.0 for 240 min, with the removal efficiency higher than 90%.

Low-frequency rTMS targeting individual self-initiated finger-tapping task activation modulates the amplitude of local neural activity in the putamen.

Repetitive transcranial magnetic stimulation (rTMS) has been used in the clinical treatment of Parkinson's disease (PD). Most of rTMS studies on PD used high-frequency stimulation; however, excessive nonvoluntary movement may represent abnormally cortical excitability, which is likely to be suppressed by low-frequency rTMS. Decreased neural activity in the basal ganglia on functional magnetic resonance imaging (fMRI) is a characteristic of PD.

An artificial remote tactile device with 3D depth-of-field sensation.

Flexible tactile neuromorphic devices are becoming important as the impetus for the development of human-machine collaboration. However, accomplishing and further transcending human intelligence with artificial intelligence still confront many barriers. Here, we present a self-powered stretchable three-dimensional remote tactile device (3D-RTD) that performs the depth-of-field (DOF) sensation of external mechanical motions through a conductive-dielectric heterogeneous structure.

Intermittent theta burst stimulation over the parietal cortex has a significant neural effect on working memory.

The crucial role of the parietal cortex in working memory (WM) storage has been identified by fMRI studies. However, it remains unknown whether repeated parietal intermittent theta-burst stimulation (iTBS) can improve WM. In this within-subject randomized controlled study, under the guidance of fMRI-identified parietal activation in the left hemisphere, 22 healthy adults received real and sham iTBS sessions (five consecutive days, 600 pulses per day for each session) with an interval of 9 months between the two sessions.

Resting-State fMRI Functional Connectivity Strength Predicts Local Activity Change in the Dorsal Cingulate Cortex: A Multi-Target Focused rTMS Study.

Previous resting state functional magnetic resonance imaging (RS-fMRI) studies suggested that repetitive transcranial magnetic stimulation (rTMS) can modulate local activity in distant areas via functional connectivity (FC). A brain region has more than one connection with the superficial cortical areas. The current study proposed a multi-target focused rTMS protocol for indirectly stimulating a deep region, and to investigate 1) whether FC strength between stimulation targets (right middle frontal gyrus [rMFG] and right inferior parietal lobule [rIPL]) and effective region (dorsal anterior cingulate cortex [dACC]) can predict local activity changes of dACC and 2) whether multiple stimulation targets can focus on the dACC via FC.

Psychometric Properties and Measurement Invariance Across Sex of the Wong and Law Emotional Intelligence Scale in Chinese adolescents.

The aim of this study was to validate the Wong and Law Emotional Intelligence Scale (WLEIS) in Chinese adolescents by examining factor structure, sex-related measurement invariance and latent mean differences, reliability, and criterion-related validity.A total of 1674 Chinese adolescents aged 12-17 years old (M = 15.26, SD = .

High-Resolution U-Net: Preserving Image Details for Cultivated Land Extraction.

Accurate and efficient extraction of cultivated land data is of great significance for agricultural resource monitoring and national food security. Deep-learning-based classification of remote-sensing images overcomes the two difficulties of traditional learning methods (e.g.

Pregenual or subgenual anterior cingulate cortex as potential effective region for brain stimulation of depression.

Background: The dorsolateral prefrontal cortex (DLPFC) is the standard stimulation target for the repetitive transcranial magnetic stimulation (rTMS) treatment of major depression disorder (MDD). A retrospective study by Fox and colleagues found that a more negative resting-state functional magnetic resonance imaging (RS-fMRI) functional connectivity (FC) between left DLPFC and the subgenual anterior cingulate cortex (sgACC) in a large group of healthy participants is associated with a better curative effects of rTMS in MDD, suggesting that the sgACC may be an effective region. However, a recent meta-analysis on RS-fMRI studies found that the pregenual ACC (pgACC), rather than the sgACC, of MDD patients showed increased local activity.

Finger Tapping Task Activation vs. TMS Hotspot: Different Locations and Networks.

Both functional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) have been used to non-invasively localize the human motor functional area. These locations can be clinically used as stimulation target of TMS treatment. However, it has been reported that the finger tapping fMRI activation and TMS hotspot were not well-overlapped.