Fabrication of high-strength and tough PLA/PBAT composites via in-situ copolymer formation using an adaptable epoxy extender.

Developing biodegradable polymers with superior mechanical performance offers a sustainable solution to address the severe environmental challenges posed by conventional plastics. Poly(lactic acid) (PLA) and poly(butylene adipate-co-terephthalate) (PBAT), two prominent biodegradable plastics, exhibit complementary mechanical properties. However, their inherent incompatibility and significant viscosity mismatch cause significant challenges for effective blending via the conventional methods.

The transcription factor MhZAT10 enhances antioxidant capacity by directly activating the antioxidant genes MhMSD1, MhAPX3a and MhCAT1 in apple rootstock SH6 (Malus honanensis × M. domestica).

Stress tolerance in apple (Malus domestica) can be improved by grafting to a stress-tolerant rootstock, such as 'SH6' (Malus honanensis × M. domestica 'Ralls Genet'). However, the mechanisms of stress tolerance in this rootstock are unclear.

Transcription factors MhDREB2A/MhZAT10 play a role in drought and cold stress response crosstalk in apple.

Drought and cold stresses seriously affect tree growth and fruit yield during apple (Malus domestica) production, with combined stress causing injury such as shoot shriveling. However, the molecular mechanism underlying crosstalk between responses to drought and cold stress remains to be clarified. In this study, we characterized the zinc finger transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 10 (ZAT10) through comparative analysis of shoot-shriveling tolerance between tolerant and sensitive apple rootstocks.

Nano-Sized Antioxidative Trimetallic Complex Based on Maillard Reaction Improves the Mineral Nutrients of Apple ( Borkh.).

The metallic complex is widely used in agricultural applications. Due to the oxidation of the metal and environmental unfriendliness of ligand, maintaining an efficient mineral supply for plants without causing environmental damage is difficult. Herein, an antioxidative trimetallic complex with high stability was synthesized by interacting Ca, Fe, and Zn with the biocompatible ligands from the Maillard reaction.

The lncRNA XIST/miR-150-5p/c-Fos axis regulates sepsis-induced myocardial injury via TXNIP-modulated pyroptosis.

Myocardial injury is a severe complication of sepsis and contributes substantially to the death of critically ill patients. Long non-coding RNAs (lncRNAs) participate in the pathogenesis of sepsis-induced myocardial injury. In this study, we investigated the role of lncRNA X-inactive specific transcript (XIST) in septic myocardial injury and explored its mechanism.

Clinical correlates of hypotension in patients with acute organophosphorus poisoning.

Background: The aim of the present study is to describe the clinical correlates of hypotension and its associated outcomes in patients with acute organophosphorus poisoning (AOPP).

Methods: In this retrospective cohort study, we analyzed data pertaining to 871 patients with AOPP who were treated at two hospitals. Data from hypotensive and non-hypotensive patients were compared to identify clinical correlates of hypotension.

A Novel Oncogenic Driver in a Lung Adenocarcinoma Patient Harboring an -KDD and Response to Afatinib.

Oncogenic mutations in the epidermal growth factor receptor () occur frequently in patients with lung cancer. These mutations may serve as critical predictive biomarkers in patients with non-small cell lung cancer (NSCLC). Among them, exon 18-25 kinase domain duplication (-KDD) mutations have been identified as a novel gene subtype in NSCLC.

Dual drive coexistence of rearrangement and mutation advanced lung adenocarcinoma and response to crizotinib.

Chromosomal translocation resulting in the fusion between the echinoderm microtubule-associated protein-like 4 () gene and the anaplastic lymphoma kinase () gene has been considered as a novel oncogenic fusion in a subset of non-small cell lung cancer (NSCLC), mostly in non-smokers with adenocarcinoma. EML4-ALK translocations are commonly reported to be mutually exclusive with epidermal growth factor receptor (EGFR) or KRAS mutations. Herein, we reported a rare case of 47-year-old female was diagnosed with lung adenocarcinoma and treated with three cycles of chemotherapy.

[Multivariate analysis of relationship between soil nutrient factors and fruit quality characte-ristic of 'Fuji' apple in two dominant production regions of China].

The objective of this experiment is to probe into the influence of soil nutrient contents on fruit quality features of 'Fuji' apple, screen major soil nutrient factors affecting fruit quality features, clarify the suitable soil nutrient content for good fruit quality indicators, and to provide theoretical basis in reasonable orchard soil fertilizer application for improving fruit qua-lity in the Circum-Bohai and Loess Plateau apple production regions in China. The soil nutrient contents and 'Fuji' fruit qualities were respectively analyzed at 66 commercial 'Fuji' apple orchards standard rootstock in the Circum-Bohai and Loess Plateau apple production regions of 22 counties in China from 2010 to 2011. The partial least squares regression (PLS) was used to screen major soil nutrient elements affecting fruit quality, and to establish regression equation of relationship between fruit quality and major soil nutrition factors.

[Preparation and optical properties of tantalum tungsten bronze].

Tantalum tungsten bronze(TaxWO3)nanowires were successfully synthesized via hydrothermal method using TaCl5 and Na2WO4 . 2H20 as raw materials. The morphology, crystal structure and optical properties of synthesized products were characterized by means of XRD, TEM, SEM, UV-Vis and Raman technologies.

In vivo monitoring of dihydroartemisinin-piperaquine sensitivity in Plasmodium falciparum along the China-Myanmar border of Yunnan Province, China from 2007 to 2013.

Background: Artemisinin-based combination therapy (ACT) is the recommended first-line treatment of falciparum malaria in all endemic countries. Artemisinin resistance in Plasmodium falciparum has been confirmed in the Greater Mekong subregion (GMS). Dihydroartemisinin-piperaquine (DAPQ) is the most commonly used ACT in China.

Monitoring Plasmodium vivax chloroquine sensitivity along China-Myanmar border of Yunnan Province, China during 2008-2013.

Background: Plasmodium vivax is the most widespread of the malaria parasites infecting human hosts. In malaria-eliminating settings, both imported and local malaria predominantly occurs in border areas, and most of them are P. vivax.

TET1 partially mediates HDAC inhibitor-induced suppression of breast cancer invasion.

Histone deacetylases (HDACs) are important in chromatin remodeling and epigenetic regulation of gene expression. Histone deacetylase inhibitors (HDACi) have highly effective anti-metastatic and anti-angiogenic activity in various types of cancer, while the molecular mechanisms involved in this process are not fully understood. In the present study, trichostatin A (TSA), a HDACi, was found to suppress MCF-7 breast carcinoma cell invasion and upregulate TET1 expression in a dose-dependent manner.

[Field evaluation of SD(BIOLINE) malaria antigen Plasmodium falciparum/Plasmodium vivax rapid test kit].

Four hundred and seventy-five patients with fever within 48 h were detected for Plasmodium using double blind field trials in China-Myanmar border from June to December 2011. The result showed that 202 of 475 were positive by SD(BIOLINE) kits, with 98 positive of Plasmodium falciparum and 104 positive of Plasmodium vivax. By microscope examination, 206 were positive.

Elevated serum ubiquitin C-terminal hydrolase-L1 levels in patients with carbon monoxide poisoning.

Objective: Ubiquitin C-terminal hydrolase-L1 (UCH-L1) has been established as a reliable and potential biomarker of neuronal damage after acute neurologic insults, such as ischemic stroke, subarachnoid hemorrhage, and traumatic brain injury. However, the effect of serum UCH-L1 levels has not been investigated in carbon monoxide (CO)-poisoned patients. The aim of the present study was to evaluate whether serum UCH-L1 levels are a reliable marker of brain damage and the association of UCH-L1 with outcome.

Characterization of sck1, a novel Castanea mollissima mutant with the extreme short catkins and decreased gibberellin.

A novel Chinese chestnut (Castanea mollissima Bl.) mutant with extreme short catkins, here was named sck1 and has been characterized in the present study. This sck1 caused 6-fold shorter than wild-type catkins.