OsBZR4 regulates temperature-dependent embryogenesis in rice.

Embryoless rice is valuable for studying early seed development and has great breeding potential, however, related research remains limited. Here, we show that mutations in OsBZR4, encoding brassinazole-resistance 4, lead to 60-100% embryoless seeds across different cultivars. OsBZR4 is specifically expressed at the scutellum-endosperm interface and regulates auxin levels and distribution during early embryo development.

[Research advances in the inhibitory effect of chondroitin sulfate proteoglycans on axon growth after premature white matter injury and its underlying mechanisms].

White matter injury (WMI) is a major form of brain injury in preterm infants. Its characteristic pathological features primarily involve impaired development of oligodendrocyte precursor cells and structural damage to axons, which can lead to the neurological sequelae such as motor, behavioral, and cognitive dysfunctions. Chondroitin sulfate proteoglycans (CSPGs), as the important components of extracellular matrix, can participate in neuroinflammatory response mediated by microglial cells and dynamically balance glial scar reconstruction and axon growth by regulating specific receptors and signaling pathways.

JMJ720 regulates flowering time in rice via H3K9 demethylation of Hd1.

Heading date is a crucial agronomic trait that determines the adaptability of rice to specific planting regions and seasons. Although numerous heading date genes have been well characterized in rice, epigenetic regulation of flowering time remains limited. In this study, we identified JmjC (Jumonji C) domain-containing gene JMJ720 as a novel heading date-regulated gene.

Precise modulation of bioactive gibberellin homeostasis: A promising strategy for enhancing abiotic stress tolerance.

This commentary discusses studies identifying three elite loci, ATT2, wrky53 and CTB5, which enhance abiotic stress tolerance and maximize grain yield under challenging environmental conditions by modulating gibberellin content. These loci could be valuable tools for developing new varieties for agricultural sustainability.

OsBSK3 and OsBSK2 regulate grain size and leaf angle via MAPK signaling pathway in rice.

Grain size and leaf angle are key agronomic traits that determine the final yield. OsBSKs (BRASSINOSTEROID-SIGNALING KINASES) and OsMAPKs (MITOGEN ACTIVATED PROTEIN KINASE) are known to play essential roles in plant growth, development, and stress responses. However, the potential crosstalk between these pathways and their specific roles in regulating grain size and leaf angle remain largely unexplored in rice.

OsBBX2 Delays Flowering by Repressing Expression Under Long-Day Conditions in Rice.

Members of the B-Box (BBX) family of proteins play crucial roles in the growth and development of rice. Here, we identified a rice BBX protein, Oryza sativa BBX2 (OsBBX2), which exhibits the highest expression in the root. The transcription of follows a diurnal rhythm under photoperiodic conditions, peaking at dawn.

Liver Fibrosis Amelioration by Macrophage-Biomimetic Polydopamine Nanoparticles via Synergistically Alleviating Inflammation and Scavenging ROS.

The progression of liver fibrosis is determined by the interaction of damaged hepatocytes, active hepatic stellate cells, and macrophages, contributing to the development of oxidative stress and inflammatory environments within the liver. Unfortunately, the current pharmacological treatment for liver fibrosis is limited by its inability to regulate inflammation and oxidative stress concurrently. In this study, we developed a cell membrane biomaterial for the treatment of liver fibrosis, which we designated as PM.

Near-Infrared Fluorescence Imaging of miRNA Using a Transmembrane Polypeptide-Based Genetic Reporter.

MicroRNAs (miRNAs) are small noncoding RNAs that play important regulatory roles in multiple biological processes. Many miRNAs exhibit unique expression patterns and are considered as theranostic biomarkers in a variety of human diseases. A reporter system that is capable of imaging miRNA in vivo is crucial for investigating miRNA biology.

Production of C-C olefins by catalytic pyrolysis of low-density polyethylene with MCM-41 in CO/N.

The current high volume of plastic waste, but low recycling rate, has led to environmental pollution and wasted energy. Greenhouse gas CO can facilitate thermal cracking to dehydrogenate waste plastics, and has potential value for producing olefins. In this work, the pyrolysis properties of low-density polyethylene (LDPE) were studied by thermogravimetric analysis and Py-GC/MS.

Transcription factor bZIP65 delays flowering via suppressing expression in rice.

Unlabelled: Flowering time is one of the most fundamental factors that determine the distribution and final yield of rice. Ehd1 (Early heading date 1) is a B-type response regulator which functions as a flowering time activator. Although diverse flowering time genes have been reported as regulatory factors of expression, the potential regulators of largely remain to be identified.

A dual-regulation inducible switch system for microRNA detection and cell type-specific gene activation.

MicroRNAs (miRNAs) play key roles in multiple biological processes, many of which exhibit distinct cell type-specific expression patterns. A miRNA-inducible expression system can be adapted as a signal-on reporter for detecting miRNA activity or as a cell type-specific gene activation tool. However, due to the inhibitory properties of miRNAs on gene expression, few miRNA-inducible expression systems are available, and the available systems are only transcriptional or post-transcriptional regulatory system with obvious leaky expression.

Clinical value of regional lymph node sorting in gastric cancer.

Background: Increasing evidence have shown that regional lymph node metastasis is a critical prognostic factor in gastric cancer (GC). In addition, lymph node dissection is a key factor in determining the appropriate treatment for GC. However, the association between the number of positive lymph nodes and area of lymph node metastasis in GC remains unclear.

Jumping is not just about height: Biosocial becomings as an integrative approach in understanding contextualized jump performance in Maasai society.

Studies focused on jumping performance in humans have so far investigated either its biological or sociocultural significance, with very little attentions paid to the inseparable relations of these two aspects in daily life of people. Integrating both ethnographic and biomechanical methods, this research investigated the biosocial features of the jump performance of Maasai youth in its most well observed context, the wedding ceremony. Ethnographic data were used to explain the social status of participants, the physical movements and singing tempo of performers, and their interactions.

STV-SC: Segmentation and Temporal Verification Enhanced Scan Context for Place Recognition in Unstructured Environment.

Place recognition is an essential part of simultaneous localization and mapping (SLAM). LiDAR-based place recognition relies almost exclusively on geometric information. However, geometric information may become unreliable when faced with environments dominated by unstructured objects.

OsMKKK70 Negatively Regulates Cold Tolerance at Booting Stage in Rice.

Cold stress at the booting stage leads to a lower seed setting rate and seriously threatens the production of rice ( L.), which has become a major yield-limiting factor in higher-altitude and -latitude regions. Because cold tolerance at the booting stage (CTB) is a complex trait and is controlled by multiple loci, only a few genes have been reported so far.

Tongue diagnostic parameters-based diagnostic signature in coronary artery disease patients with clopidogrel resistance after percutaneous coronary intervention.

Background: Credible diagnostic stratification remains a challenge for coronary artery disease patients with clopidogrel resistance after percutaneous coronary intervention. Tongue diagnostic parameters-based diagnostic signatures might predict clopidogrel resistance.

Methods: Clinical and tongue diagnostic parameters data were obtained from coronary artery disease patients with clopidogrel resistance after percutaneous coronary intervention patients and then analyzed.

Synthesis, characterization, and evaluation of microwave-assisted fabricated selenylation Astragalus polysaccharides.

Selenylation Astragalus polysaccharides (Se-APS) was fabricated by an optimized microwave-assisted method. Their physicochemical properties, antioxidant capacities and selenium (Se) release rate under gastrointestinal conditions were determined. Se-APS with the highest Se content (18.