Research status and hotspots of tight junctions and colorectal cancer: A bibliometric and visualization analysis.

Background: Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related death. Over the past two decades, numerous researchers have provided important evidence regarding the role of tight junction (TJ) proteins in the occurrence and progression of CRC. The causal relationship between the presence of specific TJ proteins and the development of CRC has also been confirmed.

Immunological factors in cirrhosis diseases from a bibliometric point of view.

Background: Cirrhosis results from persistent liver injury that leads to liver fibrosis. Immunological factors play important regulatory roles in the development and progression of cirrhosis. Bibliometrics is one of the most commonly used methods for systematic evaluation of a field of study.

Primotrapa gen. nov., an extinct transitional genus bridging the evolutionary gap between Lythraceae and Trapoideae, from the early Miocene of North China.

Background: Although Trapa is a well-defined genus of distinctive freshwater plants with accumulations of extensive morphological and embryological autapomorphies, its phylogenetic relationships have long been unclear. Formerly placed in the monotypic family Trapaceae, Trapa is now recognized as sister to Sonneratia within Lythraceae s.l.

CircRNA FGFR3 induces epithelial-mesenchymal transition of ovarian cancer by regulating miR-29a-3p/E2F1 axis.

Circular RNAs (circRNAs) are a class of non-coding RNAs that regulate gene expression after transcription. However, the specific function of circRNAs in ovarian cancer remains undetermined. Previous studies have demonstrated abnormal expression of circFGFR3 in several cancers.

Reversal of Hypoxic Pulmonary Hypertension by Hypoxia-Inducible Overexpression of Angiotensin-(1-7) in Pulmonary Endothelial Cells.

Hypoxia-induced pulmonary vascular constriction and structure remodeling are the main causes of hypoxic pulmonary hypertension. In the present study, an adeno-associated virus vector, containing Tie2 promoter and hypoxia response elements, was designed and named HTSFcAng(1-7). Its targeting, hypoxic inducibility, and vascular relaxation were examined , and its therapeutic effects on hypobaric hypoxia-induced pulmonary hypertension were examined in rats.

Extraovarian Brenner tumor in the uterus: a case report and review of literature.

Background: Extraovarian Brenner tumors (EOBTs) are extremely rare and can be observed incidentally in both female and male patients, raising concerns regarding the origin of Brenner tumors.

Case Presentation: A 53-year-old postmenopausal woman presented with a nodular lesion in the left side of the corpus uteri, which was found at a routine health check. Macroscopically, the lesion appeared as a solid nodule with a yellowish-gray cut surface, approximately 6 cm in greatest diameter.

Long Non-Coding RNA LINC01783 Promotes the Progression of Cervical Cancer by Sponging miR-199b-5p to Mediate GBP1 Expression.

Background: Long non-coding RNA showed potential regulating effects in oncogenesis. Highly expressed LncRNA LINC01783 is observed in cervical cancer. However, the specific pathogenesis of cervical cancer is still unclear.

Sequoia maguanensis, a new Miocene relative of the coast redwood, Sequoia sempervirens, from China: implications for paleogeography and paleoclimate.

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Premise Of The Study: The paleogeographical origin of the relict North American Sequoia sempervirens is controversial. Fossil records indicate a Neogene origin for its foliage characteristics. Although several fossils from the Miocene sediments in eastern Asia have been considered to have close affinities with the modern S.

An R2R3-MYB gene, LeAN2, positively regulated the thermo-tolerance in transgenic tomato.

LeAN2 is an anthocyanin-associated R2R3-MYB transcription factor, but little is known about its function in imparting thermo-tolerance to higher plants. To examine the function of LeAN2 in the regulation of heat stress in tomato, LeAN2 was isolated and transgenic tomato plants were obtained. Overexpression of LeAN2 under the control of the CaMV35S promoter in tomato induced the up-regulation of several structural genes in the anthocyanin biosynthetic pathway as well as anthocyanin accumulation in transgenic tomato plants.

[Efficacy observation on female chronic pyelonephritis treated with abdominal cluster-needling therapy].

Objective: To observe the difference in the clinical efficacy on female chronic pyelonephritis between abdominal cluster-needling therapy and western medicine so as to explore the optimal therapeutic method for the disease.

Methods: Seventy cases of female chronic pyelonephritis were randomized into an abdominal cluster-needling group and levofloxacin group, 35 cases in each one. In the abdominal cluster-needling group, the lower abdominal point was selected in combination with Zusanli (ST 36), Sanyinjiao (SP 6) and Taixi (KI 3).

The multiple stress-responsive transcription factor SlNAC1 improves the chilling tolerance of tomato.

NAC (NAM-ATAF1, 2-CUC2) family members play important roles in various environmental responses. Here, we cloned a full-length NAC gene (954 bp) from Solanum lycopersicum (SlNAC1). This gene belonged to ATAF subfamily which included ATAF1 and ATAF2 of Arabidopsis thaliana.

Lutein supplementation improves visual performance in Chinese drivers: 1-year randomized, double-blind, placebo-controlled study.

Objectives: Although it is known that the carotenoid lutein can affect visual performance, we still have much to learn about its effect in occupational populations, like drivers. The aim of this study was to examine the effect of lutein supplementation on visual function in healthy drivers with long-term light exposure.

Methods: The study was a randomized, double-blind, placebo-controlled, 1-y intervention study.

[Determination of arsenic, mercury and selenium in Gynostemma pentaphyllum and rhizospheric soil samples collected from different regions by hydride generation atomic fluorescence spectrometry].

The contents of arsenic (As), mercury (Hg) and selenium (Se) in Gynostemma pentaphyllum and rhizospheric soil samples collected from seven provinces were determined, through the optimization of the hydride generation atomic fluorescence spectrometry working conditions. The results show that: the contents of As, Hg and Se in Gynostemma pentaphyllum from seven provinces revealed large differences, but compared with the limits of the two kinds of heavy metal element: As and Hg set by the Green Trade Standards of Importing & Exporting Medicinal Plants & Preparations (As < or = 2.0 mg x kg(-1), Hg < or = 0.

[Epidemiologic study of dry eye in populations equal or over 20 years old in Jiangning District of Shanghai].

Objective: To investigate the prevalence of dry eye in populations equal or over 20 years old in Jiangning District, Shanghai, China.

Methods: This was a cross-sectional study. From September 2008 to January 2009, 6 small districts including 21,102 people of Jiangning District were randomly selected as survey venues by Department of Ophthalmology in First People's Hospital affiliated to Shanghai Jiaotong University.