Insomnia Among Patients with End-Stage Kidney Disease on Hemodialysis: Prevalence and Associated Factors - A Cross-Sectional Study in Vietnam.

Background And Aims: The prevalence of insomnia among patients with end-stage kidney disease undergoing hemodialysis is high. Insomnia in patients undergoing hemodialysis may reduce their quality of life. The purpose of this study was to estimate the prevalence of insomnia and to examine the risk factors associated with insomnia among patients with end-stage kidney disease undergoing hemodialysis.

Invasive nasal and paranasal mucormycosis in a patient with severe dengue fever and multiple risk factors: A case report and literature review.

Mucormycosis is a rare, life-threatening opportunistic fungal infection with high mortality rates that primarily affects immunocompromised patients. The co-occurrence of dengue fever and mucormycosis is extremely rare, with only a few cases reported worldwide. We report a case of a 50-year-old female diagnosed with mucormycos following dengue fever.

Enhanced stability of simulated leukocytes for hematology internal quality control samples: A material improvement.

Objectives: This study aimed to develop and evaluate simulated leukocytes derived from porcine leukocytes as a stable alternative for internal quality control (IQC) in hematology laboratories. Addressing challenges related to material stability and availability, the research contributes to improving laboratory quality assurance in Vietnam.

Methods: Statistical methods including Shapiro-Wilk test, Levene's test, t-tests, ANOVA, and the IQR method were applied to assess post-production quality and establish target values.

Risk factors for tuberculosis treatment outcomes: a statistical learning-based exploration using the SINAN database with incomplete observations.

Background: Understanding early predictors of treatment outcomes allows better outcome prediction and resource allocation for efficient tuberculosis (TB) management.

Objectives: This study aimed to predict treatment outcomes of TB patients from a real-world population-wide health record dataset with a significant rate of incomplete observations. In addition, potential risk factors associated with death during TB treatment were investigated.

Transcriptome characterisation and population genetics of Hayata - An endangered gymnosperm and implication for its conservation in Vietnam.

Biodiversity loss and degradation activities have a significant impact and devastating consequences on the ecosystem, eventually posing a major threat to many plant species, including . Deforestation and the growth of settlements are the main factors that affect the biodiversity hotspots in Vietnam such as Northwest, Northeast, North Central and Central Highlands regions. This has led to a decline of the species, so effective conservation strategies are urgently required.

A computational approach to automated dental implant placement: Bone density optimization around the implant with the Levenberg-Marquardt algorithm.

Statement Of Problem: Dental implants have been a prevalent method of restoring lost teeth and providing dental function, with recent advancements driven by computer-guided techniques. However, limitations persist concerning the evaluation of anatomic and prosthetic factors, which demand extensive expertise and manual effort.

Purpose: The purpose of this study was to evaluate an implant placement system capable of automatically suggesting optimal implant positions by enhancing stability by maximizing bone density surrounding the implant.

Examining the challenges in sustaining user engagement with a mobile app to enhance multidrug-resistant tuberculosis (MDR-TB) care in Vietnam and its implications for implementing person-centred mHealth interventions.

Digital health technologies, especially mobile application (mHealth), offer great potential for enhancing person-centred care and managing MDR-TB. The rapid expansion of digital infrastructure in Vietnam presents a valuable opportunity for such interventions. This qualitative study examines user experiences to explain reported reduction in engagement with (i.

Evaluation of state-of-the-art deep learning models in the segmentation of the left and right ventricles in parasternal short-axis echocardiograms.

Purpose: Previous studies on echocardiogram segmentation are focused on the left ventricle in parasternal long-axis views. Deep-learning models were evaluated on the segmentation of the ventricles in parasternal short-axis echocardiograms (PSAX-echo). Segmentation of the ventricles in complementary echocardiogram views will allow the computation of important metrics with the potential to aid in diagnosing cardio-pulmonary diseases and other cardiomyopathies.

Misspecification Strikes: ASTRAL can Mislead in the Presence of Hybridization, even for Nonanomalous Scenarios.

ASTRAL is a powerful and widely used tool for species tree inference, known for its computational speed and robustness under incomplete lineage sorting. The method has often been used as an initial step in species network inference to provide a backbone tree structure upon which hybridization events are later added to such a tree via other methods. However, we show empirically and theoretically, that this methodology can yield flawed results.

An mHealth app technology to strengthen adverse event management of multi-drug-resistant tuberculosis in Vietnam: Protocol for a process evaluation of the V-SMART trial.

Background: Drug-related adverse events cause poorer treatment outcomes amongst people with multi-drug-resistant tuberculosis, exacerbating a major global public health problem. The Harnessing new mHealth technologies to Strengthen the Management of Multi-Drug-Resistant Tuberculosis in Vietnam (V-SMART) trial tests whether a mobile health (mHealth) application (app) can optimise management of drug-related adverse events, within routine health services in Vietnam. Implementation of digital health within routine services is complex and driven by behaviour change as well as a range of health system factors.

Design, synthesis, anti-inflammatory evaluation, and molecular docking studies of novel quinazoline-4(3)-one-2-carbothioamide derivatives.

In this paper, a series of novel quinazoline-4(3)-one-2-carbothioamide derivatives (8a-p) were designed and synthesized the Wilgerodt-Kindler reaction between 2-methylquinazoline-4-one 10 and amines using S/DMSO as the oxidizing system. Their characteristics were confirmed by IR, NMR, HRMS spectra, and their melting point. These novel derivatives (8a-p) were evaluated for their anti-inflammatory activity by inhibiting NO production in lipopolysaccharide (LPS)-activated RAW 264.

Portrait of a Cerebral Killer.

: Primary amebic meningoencephalitis (PAM) caused by is a rare and devastating infection of the central nervous system, often diagnosed late, due to its rapid progression and nonspecific symptoms. We report one of the youngest documented pediatric Vietnamese cases of PAM in a 10-month-old girl from the Mekong Delta, Vietnam. The diagnosis was confirmed through multiplex real-time PCR (MPL-rPCR), microscopy, and sequencing.

BLEscope: A Bluetooth Low Energy (BLE) Microscope for Wireless Multicontrast Functional Imaging.

Recent advances in low-power wireless-capable system-on-chips (SoCs) have accelerated diverse Internet of Things (IoT) applications, encompassing wearables, asset monitoring, and more. Concurrently, the field of neuroimaging has experienced escalating demand for lightweight, untethered, low-power systems capable of imaging in small animals. This article explores the feasibility of using a low-power asset monitoring system as the basis of a new architecture for fluorescence and hemodynamic contrast-based wireless functional imaging.

Novel Water Probe for High-Frequency Focused Transducer Applied to Scanning Acoustic Microscopy System: Simulation and Experimental Investigation.

A scanning acoustic microscopy (SAM) system is a common non-destructive instrument which is used to evaluate the material quality in scientific and industrial applications. Technically, the tested sample is immersed in water during the scanning process. Therefore, a robot arm is incorporated into the SAM system to transfer the sample for in-line inspection, which makes the system complex and increases time consumption.

Mapping adipose tissue in short-axis echocardiograms using spectral analysis.

The number one cause of death in the United States is consistently cardiovascular disease (CVD). Studies have proven that the buildup of cardiac adipose tissue (CAT) around the heart is a biomarker of CVD. MRI is the gold standard for imaging CAT but is expensive and not widely available.

Characterisation of the (Jack) Meisn (Lauraceae) transcriptome using Illumina paired-end sequencing and EST-SSR markers development for population genetics.

is an endemic and endangered species with significant economic and ecological value in Vietnam. A better understanding of the genetic architecture of the species will be useful when planning management and conservation. We aimed to characterize the transcriptome of , develop novel molecular markers, and assess the genetic variability of the species.

Antibiotic Resistance, Biofilm Formation, and Persistent Phenotype of in a Vietnamese Tertiary Hospital: A Focus on Amikacin.

stands out as a major opportunistic pathogen responsible for both hospital- and community-acquired bacterial infections. This study comprehensively assesses the antibiotic resistance, amikacin persistent patterns, and biofilm-forming ability of 247 isolates of obtained from an intensive care unit of a tertiary hospital in Vietnam. Microdilution assays, conducted on a 96-well plate, determined the minimum inhibitory concentrations (MICs) of amikacin.

The amphipathic design in helical antimicrobial peptides.

Amphipathicity is a critical characteristic of helical antimicrobial peptides (AMPs). The hydrophilic region, primarily composed of cationic residues, plays a pivotal role in the initial binding to negatively charged components on bacterial membranes through electrostatic interactions. Subsequently, the hydrophobic region interacts with hydrophobic components, inducing membrane perturbation, ultimately leading to cell death, or inhibiting intracellular function.

RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung metastases.

One-third of pediatric patients with osteosarcoma (OS) develop lung metastases (LM), which is the primary predictor of mortality. While current treatments of patients with localized bone disease have been successful in producing 5-year survival rates of 65-70%, patients with LM experience poor survival rates of only 19-30%. Unacceptably, this situation that has remained unchanged for 30 years.

Pentacyclic triterpenes from the leaves of Ninh.

Nine pentacyclic triterpene derivatives including new 3-coumaroyl trichadenic acid B () and two new ursane-type triterpene derivatives, 11,12-[1-(methyl)-2-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3-ol () and 11,12-[2-(methyl)-1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-dioxy]-urs-12-ene-3-ol () were isolated from the leaves of Ninh., along with six known compounds (). This is the first report on pentacyclic triterpenoids from this species.

Metabolic phenotyping and global functional analysis facilitate metabolic signature discovery for tuberculosis treatment monitoring.

Tracking alterations in polar metabolite and lipid levels during anti-tuberculosis (TB) interventions is an emerging biomarker discovery and validation approach due to its sensitivity in capturing changes and reflecting on the host status. Here, we employed deep plasma metabolic phenotyping to explore the TB patient metabolome during three phases of treatment: at baseline, during intensive phase treatment, and upon treatment completion. Differential metabolites (DMs) in each period were determined, and the pathway-level biological alterations were explored by untargeted metabolomics-guided functional interpretations that bypassed identification.

The effect of magnetic bead size on the isolation efficiency of lung cancer cells in a serpentine microchannel with added cavities.

An investigation was conducted to examine the effect of magnetic bead (MB) size on the effectiveness of isolating lung cancer cells using the immunomagnetic separation (IMS) method in a serpentine microchannel with added cavities (SMAC) structure. Carboxylated magnetic beads were specifically conjugated to target cells through a modification procedure using aptamer materials. Cells immobilized with different sizes (in micrometers) of MBs were captured and isolated in the proposed device for comparison and analysis.

mHealth application for improving treatment outcomes for patients with multidrug-resistant tuberculosis in Vietnam: an economic evaluation protocol for the V-SMART trial.

Introduction: The Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART) trial is a randomised controlled trial of using mobile health (mHealth) technologies to improve adherence to medications and management of adverse events (AEs) in people with multidrug-resistant tuberculosis (MDR-TB) undergoing treatment in Vietnam. This economic evaluation seeks to quantify the cost-effectiveness of this mHealth intervention from a healthcare provider and societal perspective.

Methods And Analysis: The V-SMART trial will recruit 902 patients treated for MDR-TB across seven participating provinces in Vietnam.

A regional approach for health risk assessment of toxicants in plastic food containers.

Unlabelled: Plastic food containers are being used popularly, generating a waste of about 115 million tons in Vietnam. Such waste is causing environmental and health issues. This study conducted a field survey with 250 local people and selected 59 samples out of 135 plastic food containers collected in Go Vap district, Vietnam.