Early detection through screening is critical for reducing gastric cancer (GC) mortality. However, in most high-prevalence regions, large-scale screening remains challenging due to limited resources, low compliance and suboptimal detection rate of upper endoscopic screening. Therefore, there is an urgent need for more efficient screening protocols.
View Article and Find Full Text PDFChondroblastoma is a rare benign tumor that typically arises in the epiphyses or apophyses of long bones in patients with immature skeletal structures. Occasionally, it presents in atypical sites such as the bones of the foot and craniofacial region. This report details the case of an 18-year-old female who experienced neck pain and was found to have a lesion in the left jugular foramen.
View Article and Find Full Text PDFObjective: This study aimed to evaluate and compare the effects of sevoflurane + remifentanil (Sev + Rem) and propofol + remifentanil (Pro + Rem) on the postoperative recovery quality of patients undergoing laparoscopic bariatric surgery to determine which anesthesia regimen provides a better overall recovery experience.
Methods: Sixty patients were divided into two groups based on the treatments they underwent: Sev + Rem ( = 30) and Pro + Rem ( = 30). The Sev + Rem group received sevoflurane inhalation (0.
Drug transmission through the blood-brain barrier (BBB) is considered an arduous challenge for brain injury treatment following the return of spontaneous circulation after cardiac arrest (CA-ROSC). Inspired by the propensity of melanoma metastasis to the brain, B16F10 cell membranes are camouflaged on 2-methoxyestradiol (2ME2)-loaded reactive oxygen species (ROS)-triggered "Padlock" nanoparticles that are constructed by phenylboronic acid pinacol esters conjugated D-a-tocopheryl polyethylene glycol succinate (TPGS-PBAP). The biomimetic nanoparticles (BM@TP/2ME2) can be internalized, mainly mediated by the mutual recognition and interaction between CD44v6 expressed on B16F10 cell membranes and hyaluronic acid on cerebral vascular endothelial cells, and they responsively release 2ME2 by the oxidative stress microenvironment.
View Article and Find Full Text PDFMed Image Anal
October 2023
Self-supervised representation learning (SSL) has achieved remarkable success in its application to natural images while falling behind in performance when applied to whole-slide pathological images (WSIs). This is because the inherent characteristics of WSIs in terms of gigapixel resolution and multiple objects in training patches are fundamentally different from natural images. Directly transferring the state-of-the-art (SOTA) SSL methods designed for natural images to WSIs will inevitably compromise their performance.
View Article and Find Full Text PDFExamination of pathological images is the golden standard for diagnosing and screening many kinds of cancers. Multiple datasets, benchmarks, and challenges have been released in recent years, resulting in significant improvements in computer-aided diagnosis (CAD) of related diseases. However, few existing works focus on the digestive system.
View Article and Find Full Text PDFIn this Letter, we propose a fiber-optic radio frequency (RF) transfer based on active phase noise compensation adopting a carrier suppressed double-sideband (CSDSB) signal. The forward CSDSB signal is generated based on the transmitted RF signal at the local site to discriminate from the backward RF signal. The forward and backward signals are transmitted over the same fiber with the same wavelength to guarantee the bidirectional propagation symmetry.
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