Assessment of first-trimester insulin resistance indices for gestational diabetes mellitus: a prospective cohort study.

Background: Insulin resistance (IR) is a significant factor in gestational diabetes mellitus (GDM) development. The triglyceride-glucose (TyG) index, triglyceride-glucose body mass index (TyG-BMI), atherogenic index of plasma (AIP), and metabolic score for insulin resistance (METS-IR) are simple and reliable surrogates for assessing IR, but their predictive potential for GDM remains unexplored.

Methods: Data from 46,992 singleton pregnancies delivered at Beijing Obstetrics and Gynecology Hospital between 2018 and 2022 were prospectively collected.

Association Between Triglyceride-glucose Index, Its Trajectories and the Risk of Large for Gestational Age - Beijing Municipality, China, 2018-2022.

What Is Already Known About This Topic?: Large for gestational age (LGA) presents significant risks for both mothers and children. Studies have shown a positive association between the first trimester triglyceride-glucose (TyG) index and LGA risk.

What Is Added By This Report?: The TyG index in all three trimesters is positively associated with the risk of LGA.

Clinical Application of Ventricular Intracranial Pressure Monitoring in the Treatment of Ruptured Anterior Circulation Aneurysms: A Retrospective Study.

To evaluate the clinical effectiveness of ventricular intracranial pressure (ICP) monitoring in the treatment of ruptured anterior circulation aneurysms and to explore its impact on intracranial pressure control, postoperative complications, length of hospital stay, and neurological recovery.  Methods: A retrospective analysis was conducted on 67 patients who underwent surgical clipping for ruptured anterior circulation aneurysms at Jinjiang Hospital, Fujian Province, between January 2021 and June 2024. The patients were divided into an experimental group (32 patients) and a control group (35 patients).

Gestational diabetes mellitus is associated with distinct folate-related metabolites in early and mid-pregnancy: A prospective cohort study.

Aims: This study aimed to evaluate the association between gestational diabetes mellitus (GDM) and circulating folate metabolites, folic acid (FA) intake, and the methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) genotype.

Materials And Methods: A prospective pregnancy cohort study was conducted in Beijing, China, from 2022 to 2023. Circulating folate metabolites, including red blood cell (RBC) 5-methyltetrahydrofolate (5-MTHF), 5, 10-methylene-tetrahydrofolate (5,10-CH2-THF), 5- formyltetrahydrofolate (5-CHO-THF), and unmetabolised folic acid (UMFA), and plasma homocysteine (HCY), 5-MTHF, and methylmalonic acid (MMA), were determined at 6-17 weeks and 20-26 weeks of gestation.

Associations of gestational weight gain with birth weight outcomes in early pregnancy weight loss women: Findings from the Beijing Birth Cohort Study.

Objective: To explore the relationship between gestational weight gain (GWG) and birth weight outcomes and establish suggested GWG patterns in early pregnancy weight loss women.

Methods: This retrospective study was conducted based on the Beijing Birth Cohort Study from 2014 to 2021 and included 20 688 women. Weight change in early pregnancy was calculated using weight measurements within 16 weeks of gestation.

Association between serum lipid profile during the first and second trimester of pregnancy as well as their dynamic changes and gestational diabetes mellitus in twin pregnancies: a retrospective cohort study.

Background: Abnormal lipid metabolism is associated with gestational diabetes mellitus (GDM) in singleton pregnancies. Data were lacking on twin pregnancies with GDM. We explored the association between serum lipid profiles in the first and second trimesters as well as their dynamic changes and GDM in twin pregnancies.

The Caprini Risk Score for Early Prediction of Mortality in Patients With Acute Coronary Syndrome.

Background: The Caprini Risk Score (CRS) is a validated predictive instrument for venous thrombosis. Previous investigators have shown that a high CRS is associated with a higher risk of mortality from thrombotic diseases.

Objective: The aim of this study was to assess the association between the CRS and prognosis of patients with acute coronary syndrome (ACS).

Barthel Index as a Predictor of Mortality in Patients with Acute Coronary Syndrome: Better Activities of Daily Living, Better Prognosis.

Background: The Barthel index (BI) is a widely used assessment tool for evaluating physical performance in activities of daily living (ADL). The association between BI scores and mortality in hospital and during follow-up of acute coronary syndrome (ACS) patients remains unclear. The present study investigated whether the BI score could be used as a predictor for mortality of ACS.