Construction of a Fluorescence-Based Logic Gate Seeing the Effect of Perchlorate Ions on Hemicyanine Dye-β-Cyclodextrin Complexes to Certify Safe Drinking Water.

Perchlorate ions (ClO ) are prevalent contaminants in the surface, and drinking water that disrupt thyroid function by competitively inhibiting the sodium-iodide symporter (NIS), posing significant health risks. Here, fluorescence-based logic gates have been constructed by leveraging the binding interactions between a hemicyanine dye, 4-[4-(dimethylamino)-styryl]-1-docosylpyridinium bromide (DASPC22) and β-cyclodextrin (β-CD) that could be useful to know whether ClO ions in water are within the toxicity range or not. In aqueous media, DASPC22 forms nonfluorescent H-aggregates, but fluorescence is enhanced upon forming host-guest inclusion complexes with β-CD.

ct-DNA compaction by nanoparticles formed by silica and gemini surfactants having hydroxyl group substituted spacers: In vitro, in vivo, and ex vivo gene uptake to cancer cells.

Hybrid nanoparticles formed by Silica (SiO) coated with cationic gemini surfactants with variable hydroxyl group substituted spacers, 12-4(OH)-12,2Br and 12-4(OH)-12,2Br have shown a great extent of compaction of calf thymus DNA (ct-DNA) compared to conventional counterpart cationic surfactant, dodecyl trimethylammonium bromide (DTAB). Study shows not only the hydrophobicity of the spacer but also the hydrogen bonding interactions between the hydroxyl group substituted spacer and DNA have a great role in DNA compaction. 12-4(OH)-12,2Br is more efficient in compacting ct-DNA compared to 12-4(OH)-12,2Br due to the stronger binding of the former with ct-DNA than the latter.

Compaction of Calf Thymus DNA by a Potential One-Head-Two-Tail Surfactant: Properties of Nanomaterials and Biological Testing for Gene Delivery.

A one-head-two-tail cationic surfactant, Dilauryldimethylammonium bromide (DDAB) has shown a great extent of calf thymus DNA (ct-DNA) compaction being adsorbed on the surfaces of negatively charged SiO nanoparticles (NPs). DDAB molecules show high adsorption efficiency and induce many positive surface charges per-unit surface area of the SiO NPs compared to cationic Gemini (12-6-12) and conventional (DTAB) surfactants in an aqueous medium at pH 7.4, as evident from zeta potential and EDAX data.

Binding interactions and FRET between bovine serum albumin and various phenothiazine-/anthracene-based dyes: a structure-property relationship.

The present study demonstrates binding interactions and Förster resonance energy transfer (FRET) between bovine serum albumin (BSA) and a series of structurally and electronically diverse phenothiazine (PTZ) and anthracene (ANT) dyes. Upon selective excitation of tryptophan (Trp) residues of BSA, radiationless energy transfer to a dye takes place, resulting in fluorescence quenching of the former. Fluorescence quenching mechanisms, FRET parameters, possible locations, and binding constants of dyes with the BSA have been examined to deduce a structure-property relationship.

Role of Different States of Solubilized Water on Solvation Dynamics and Rotational Relaxation of Coumarin 490 in Reverse Micelles of Gemini Surfactants, Water/12--12.2Br ( = 5, 6, 8)/-Propanol/Cyclohexane.

The present study demonstrates how the different states of solubilized water viz. quaternary ammonium headgroup-bound, bulklike, counterion-bound, and free water in reverse micelles of a series of cationic gemini surfactants, water/12--12 ( = 5, 6, 8).2Br/-propanol/cyclohexane, control the solvation dynamics and rotational relaxation of Coumarin 490 (C-490) and microenvironment of the reverse micelles.

Study on metal nanoparticles synthesis and orientation of gemini surfactant molecules used as stabilizer.

In the present study, we report the synthesis of gold (Au), silver (Ag), and gold-silver alloy (Au-Ag) nanoparticles (NPs) by seed-mediated method using gemini surfactant, containing diethyl ether spacer group as a stabilizer. As-synthesized NPs are found very much stable and have been characterized using UV-vis spectroscopy, X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), energy dispersive spectroscopy (EDS), and zeta potential techniques. The orientation of gemini surfactant molecules surrounding the metal NPs has been investigated exploiting twisted intramolecular charge transfer (TICT) fluorescence properties of a probe 4-(N,N-dimethylamino) cinnamaldehyde (DMACA).