Unveiling the photocatalytic water splitting over metal-free g-CN/γ-BNyne heterostructures using non-adiabatic molecular dynamics.

We herein computationally designed a metal-free graphitic carbon nitride/γ-boron nitride (g-CN/γ-BNyne) heterostructure as a promising photocatalyst for overall water splitting and sustainable hydrogen fuel production. The heterostructure shows type-II band energy alignment and significant optical absorption in UV and near-visible regions. The studies on excited state dynamics show that the low nonadiabatic coupling between the VBM and CBM in the heterostructure and the faster decoherence time (22.

Vacancy Defect-Assisted Enhanced Nitrogen Fixation in Metal-Free 2D Orthorhombic Boron Nitride: Insights from Nonadiabatic Molecular Dynamics Simulations.

The photocatalytic nitrogen reduction reaction (NRR) is a promising approach for green and sustainable ammonia (NH) production under ambient conditions. However, the design of highly efficient photocatalysts remains a significant challenge owing to the inertness of N molecules, complex reaction kinetics, and substantial energy barriers. In this work, we investigate the catalytic mechanism and real-time photocarrier dynamics of NRR on pristine and defect-engineered orthorhombic boron nitride (o-BN), a metal-free and environmentally friendly 2D semiconductor.

Optic Nerve Sheath Diameter Estimation to Detect Increased Intracranial Pressure in Traumatic Brain Injury patients at a Level I Trauma Center in Eastern India.

Objective: To evaluate the diagnostic accuracy of optic nerve sheath diameter (ONSD) measured by ultrasound as a non-invasive marker for detecting elevated intracranial pressure (ICP) in patients with traumatic brain injury (TBI), based on clinical and radiological findings.

Methods: This diagnostic accuracy study included 180 adult patients with isolated TBI admitted to a Level I Trauma Centre in Eastern India. ONSD was measured bilaterally using a 7.

Diffusion Tensor Imaging of the Auditory Pathway in Prelingual Deaf Children in Comparison to Normal Hearing Children in the 1 to 7 Years of Age Group.

 This article aims to determine the microstructural alterations in the auditory pathway in prelingual deaf children using diffusion tensor imaging (DTI)-derived parameters-fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and secondarily to evaluate these changes in rubella and cytomegalovirus (CMV) positive cases.  A consecutive series of consenting deaf and normal children between 1 and 7 years of age, forming the case and control groups, respectively, underwent DTI, audiological tests, and testing for rubella, CMV, and toxoplasma infections. FA and ADC were measured at four locations bilaterally: lateral lemniscus (LL), inferior colliculus, medial geniculate body, and auditory cortex (AC).

Prevalence of Osteoporosis in Postmenopausal Type 2 Diabetic Women with Diabetic Peripheral Neuropathy.

Introduction: There is evidence that diabetic peripheral neuropathy (DPN) is associated with increased risk for fractures in type 2 diabetes mellitus (T2DM). We planned a study to assess the prevalence of osteoporosis and vertebral fractures (VFs) in postmenopausal type 2 diabetic women aged 40-60 years with DPN and to find out their relationship with severity of DPN.

Methods: This cross-sectional observational study included sixty-two postmenopausal type 2 diabetic women of age 40-60 years, out of them thirty-two were with DPN and thirty were without DPN.

Xylooligosaccharides mediated gut microbiome modulation: prebiotics to postbiotics.

An increasing trend toward harnessing nutraceuticals as food supplements rather than pharmaceuticals as curative and preventive agents against various ailments has been observed. Owing to their health benefits, prebiotics have received notable attention from the pharmaceutical and food industries. Among the different prebiotic oligosaccharides, xylooligosaccharides (XOS) exhibited a remarkable capacity to stimulate the growth of the gut microbiota and benefit individuals with metabolic abnormalities.

The Missing M Band: Is it Really Non Secretory Multiple Myeloma?

Background: Non-secretory multiple myeloma (NSMM) is defined as clonal bone marrow plasma cells ≥10% or biopsy proven plasmacytoma, evidence of end-organ damage due to underlying plasma cell dyscrasia, namely hypercalcemia, renal insufficiency, anaemia, bone lesions and lack of serum and urinary monoclonal protein on electrophoresis and immunofixation. They represent 3-5% of multiple myeloma (MM). With the advent of serum free light chain (s FLC) measurement, most of NSMMs have been classified as Light chain Multiple myeloma (LCMM).

(Boiss.) Pimenov & Kljuykov from Indian Western Himalaya: impact of geographical locations on essential oil yield, chemical diversity, anti-bacterial, anti-diabetic and anti-oxidant activities.

The present study investigated the effect of different geographical locations on the seeds of (Boiss.) Pimenov & Kljuykov essential oil (EO) yield, chemical profile and their anti-bacterial, anti-oxidant and anti-diabetic potentials . The samples collected from three locations in Lahaul and Spiti regions, .

Fate of hepatic ectopic pregnancy 1-year post-treatment: still visible.

Abdominal pregnancies, 1% of all ectopic pregnancies, present diagnostic complexities with a significant risk of intraperitoneal haemorrhage and mortality. Hepatic occurrences are exceptionally uncommon, with treatment strategies less established.A woman in her early 30s and third pregnancy underwent laparotomy due to haemoperitoneum suspecting an ectopic pregnancy, but normal pelvic structures were observed.

Black rice bioactive with multifunctional health promotional activities: A special reference to wound healing activity with polyhydroxybutyrate composite.

Black rice (BR) extract contains several functional food bioactive components that are health-promoting. This study assessed the multifunctional bioactivities of various BR extracts (methanol, ethanol, acetone, and aqueous). These BR extracts revealed significant antioxidant and antibacterial activity against various bacterial strains.

Combating micro/nano plastic pollution with bioplastic: Sustainable food packaging, challenges, and future perspectives.

The widespread use of plastic in food packaging provides significant challenges due to its non-biodegradability and the risk of hazardous chemicals seeping into food and the environment. This highlights the pressing need to come up with alternatives to traditional plastic that prioritize environmental sustainability, food quality, and safety. The current study presents an up-to-date examination of micro/nano plastic (MP/NP) consumption and their associated toxicity to human health, while also considering bioplastic as safer and eco-friendly alternative materials for packaging.

A Prospective Clinical Study Investigating the Relationship between Periodontal Disease and the Progression of Chronic Kidney Disease in Renal Transplant Recipients.

Background: Periodontal disease and chronic kidney disease (CKD) are both prevalent conditions with significant implications for public health. This prospective clinical study aimed to explore the potential relationship between periodontal disease and the progression of CKD in renal transplant recipients.

Materials And Methods: A total of 150 renal transplant recipients with varying degrees of periodontal disease were enrolled in this study.

Controlling the Charge Carrier Dynamics of o-BN Monolayer through Pnictogen Family Atoms Doping.

In the quest for an efficient solar energy harvester, one should focus on materials that have a large carrier lifetime. Using time-domain density functional theory combined with nonadiabatic molecular dynamics simulations, we herein established that single-atom doping from the pnictogen family can effectively alter the electron-hole recombination time in o-BN monolayer as compared to pristine sheet. Our study reveals that with increasing the mass of the dopant atoms, the carrier lifetime increases.

Applicability of ChOLE staging to preoperative HRCT temporal bone in chronic otitis media with cholesteatoma.

Purpose: Chronic otitis media with cholesteatoma is a frequent disease entity in otology, requiring surgery in overwhelming majority of cases. Despite the huge burden there is no established grading system available to assess the severity and extent of disease preoperatively until date. Aim of our study is to assess the applicability of ChOLE staging to preoperative HRCT temporal bone in Chronic otitis media with cholesteatoma.

Cutting-Edge Developments and Patent Trends in Microspheres Drug Delivery: A Comprehensive Overview.

Microspheres have emerged as innovative drug delivery platforms with significant potential to improve the therapeutic efficacy of drugs with limited aqueous solubility and prolong their release. This abstract provides an overview of recent developments and patents granted in microsphere research, highlighting key trends and innovative approaches. Recent studies have focused on various aspects of microspheres, including formulation techniques, materials selection, and their applications in drug delivery.

The Distribution Patterns of Rhesus (Rh) Antigens.

Introduction: The determination of one's blood group is dictated by the inheritance-based diversity in the presence or absence of RBC antigens on the surface. Extended Rhesus (Rh) antigens are the most clinically relevant antigens of blood group systems after the ABO blood group system in transfusion medicine. The aim of this study was to serologically assess the prevalence of extended Rh antigens across diverse blood group systems.

Comprehensive polyphenolic profiling, antioxidant, antimicrobial, and cytotoxicity studies of (L.) Blume: a medicinal orchid.

(L.) Blume, commonly known as the Foxtail orchid, has garnered worldwide attention for its diverse medicinal properties. In this study, root extract and its fractions were evaluated for total polyphenols, flavonoids, targeted polyphenols, and antioxidant potential.

Image-Guided Percutaneous Sclerotherapy for Orbital Low-Flow Malformation: Our Experience.

For a safe sclerotherapy session to be completed in the orbital low-flow malformation (namely lymphovenous malformation or venolymphatic malformation), accurate identification of the target lesion for the drug injection is crucial. Regarding the dependability and viability of the injection approach, the authors have discussed their experiences with image-guided percutaneous sclerotherapy on a few patients.

Lysine and citric acid based pegylated polymeric dendritic nano drug delivery carrier and their bioactivity evaluation.

The main objective of this work is to synthesize multifunctional nanodendritic structural molecules that can effectively encapsulate hydrophilic as well as hydrophobic therapeutic agents. Four different types of fourth-generation lysine-citric acid based dendrimer have been synthesized in this work: PE-MC-Lys-CA-PEG, TMP-MC-Lys-CA-PEG, PE-MS-Lys-CA-PEG, and TMP-MS-Lys-CA-PEG. The antibacterial drug cefotaxime (CFTX) was further conjugated to these dendrimers.

Hot carrier relaxation dynamics of an aza-covalent organic framework during photoexcitation: An insight from ab initio quantum dynamics.

In order to develop an efficient metal-free solar energy harvester, we herein performed the electronic structure calculation, followed by the hot carrier relaxation dynamics of two dimensional (2D) aza-covalent organic framework by time domain density functional calculations in conjunction with non-adiabatic molecular dynamics (NAMD) simulation. The electronic structure calculation shows that the aza-covalent organic framework (COF) is a direct bandgap semiconductor with acute charge separation and effective optical absorption in the UV-visible region. Our study of non-adiabatic molecular dynamics simulation predicts the sufficiently prolonged electron-hole recombination process (6.

Point defect-mediated hot carrier relaxation dynamics of lead-free FASnI perovskites.

In search of a promising optoelectronic performance, we herein investigated the hot carrier relaxation dynamics of a lead-free cubic phased bulk formamidinium tin triiodide (FASnI) perovskite. To gain detailed theoretical insights, we should estimate the carrier relaxation dynamics of this pristine perovskite. To control the dynamics, point defects like central tin (Sn), iodine(I) anions, and formamidinium (FA) cations were introduced.

Survival benefit of exenteration in COVID-19-associated rhino-orbital mucormycosis.

Purpose: There has been a sudden increase in the number of rhino-orbital mucormycosis cases, primarily affecting patients recovering from COVID-19 infection. The local health authorities have declared the current situation an epidemic. In this study, we assess the role of exenteration in preventing disease progression and improving survival in patients with rhino-orbital mucormycosis.

Biochemical characterization of glutaminase-free L-asparaginases from Himalayan Pseudomonas and Rahnella spp. for acrylamide mitigation.

L-asparaginase having low glutaminase activity is important in clinical and food applications. Herein, glutaminase-free L-asparaginase (type I) coding genes from Pseudomonas sp. PCH182 (Ps-ASNase I) and Rahnella sp.

Port Site Morbidities Following the Extraction of the Gallbladder from the Umbilical Port in Comparison to the Epigastric Port in Laparoscopic Cholecystectomy: A Double-Blinded, Randomized Controlled Trial.

Background Port site morbidities after laparoscopic cholecystectomy may be related to the port used for the extraction of the gallbladder. Prior randomized trials that tried to address the suitable port for gallbladder extraction showed mixed results favouring epigastric, whereas others favoured umbilical. Thus, the present study was conducted with the aim of finding a suitable port for gallbladder extraction after laparoscopic cholecystectomy.

Evaluation of Shear Bond Strength of Orthodontic Brackets Bonded with Different Adhesives.

Background: To endure the orthodontic forces used throughout treatment, the bond strength of bonded orthodontic brackets must be enough with assessment of shear bond strength when bonding orthodontic brackets with various adhesives.

Materials And Methods: Overall, forty extracted premolars due to orthodontic treatment were included. They were split into four equal cohorts with various primers.