Publications by authors named "Si-Yuan Yao"

It is still unclear how polystyrene nanoplastics (Ps-NPs) go through plant cell, and its physiological consequence and molecular mechanisms. To address this issue, the seedlings of tartary buckwheat (Fagopyrum tataricum) were exposed to hydroponic solution with 100 mg/L fluorescent-labeled Ps-NPs (100-nm diameter) across 0-2-4-6-8 days. Laser confocal microscopy, scanning electron microscopy and transmission electron microscope illuminated that Ps-NPs can go through root cells and cause significant physiological responses with time.

View Article and Find Full Text PDF

Objective To investigate the clinical symptoms experienced by patients with thoracic spinal tumors and verify the associated symptoms that are predictive of a decline in muscle strength in the lower limbs. Methods A single-center, retrospective cross-sectional study was conducted on in-patients diagnosed with epidural thoracic spinal tumors between January 2011 and May 2021. The study involved a review of electronic medical records and radiographs and the collection of clinical data.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the glycine-serine-alanine repeat, specifically the SNP-9 peptide, and its role in neurodegenerative diseases like Alzheimer's, highlighting its potential as a therapeutic target.
  • Researchers utilized various models, including transgenic mice and cell lines, to evaluate SNP-9's effects on amyloid β levels and tau hyperphosphorylation.
  • Findings suggest SNP-9 is neuroprotective, acting by reducing toxic Aβ oligomers and interacting with calcyclin-binding protein, presenting a promising avenue for Alzheimer's treatment development.
View Article and Find Full Text PDF

Our understanding of the mechanisms underlying process in Alzheimer's disease (AD) is far from completion and new therapeutic targets are urgently needed. Recently, the link between dementia and diabetes mellitus (DM) prompted us to search for new therapeutic strategies from glucose metabolism regulators for neurodegeneration. Previous studies have indicated that fibroblast growth factor 21 (FGF21), an attractive and potential therapeutic treatment for DM, may exert diverse effects in the central nervous system.

View Article and Find Full Text PDF

Both microscopic and endoscopic transsphenoidal surgery are effective approaches for nonfunctioning pituitary adenomas. The issue on the comparison of their efficacy and safety remains inconsistent. A thorough search of the literatures (PubMed, EMBASE, MEDLINE) were performed up to March 2017.

View Article and Find Full Text PDF

Purpose: Laparoscopic surgery is emerging as an alternative to open surgery for treating acute small bowel obstruction (SBO). While postoperative adhesion is the most frequent etiology, the optimum treatment for all types of SBO needs to be evaluated.

Methods: A retrospective review was performed of 110 consecutive patients who underwent laparoscopic surgery at our institution between 2009 and 2015.

View Article and Find Full Text PDF

Postoperative celiac artery stenosis (CAS) rarely occurs in the absence of vascular injury or pseudoaneurysm after pancreatoduodenectomy (PD). Because of its low incidence, the optimal treatment for non-traumatic postoperative CAS is unknown. Here, we show a case of CAS possibly due to exacerbated median arcuate ligament compression after PD.

View Article and Find Full Text PDF

Superior mesenteric artery (SMA) syndrome is defined as a compression of the third portion of the duodenum by the abdominal aorta and the overlying SMA. SMA syndrome associated with anorexia nervosa has been recognized, mainly among young female patients. The excessive weight loss owing to the eating disorder sometimes results in a reduced aorto-mesenteric angle and causes duodenal obstruction.

View Article and Find Full Text PDF

Introduction: Ingestion of foreign bodies is a relatively common clinical problem. Blister packs have been known to be a causative agent of gastrointestinal perforation. We report a rare case of duodenal perforation caused by a blister pack, which was complicated by retroperitoneal abscess and having a poor outcome.

View Article and Find Full Text PDF

With accumulated surgical experience, the contraindications to laparoscopic surgery have been decreasing. Reduced port laparoscopic surgery has been widely adopted for a variety of diseases. However, surgery in patients with anatomic deformities are still a challenge for surgeons, specifically abdominal surgery in patients with severe kyphosis.

View Article and Find Full Text PDF

Toxic epidermal necrolysis (TEN) is a severe adverse drug reaction, which is characterized by erythema, blisters, and/or erosions of the mucous membranes and skin, but intestinal involvement is rare. In contrast, pneumatosis cystoides intestinalis (PCI) is a rare condition associated with a wide variety of underlying diseases, but to date no patient has presented with PCI associated with TEN. A 55-year-old man was admitted to intensive care unit for treatment of TEN caused by phenobarbital.

View Article and Find Full Text PDF