Genetic Variants in Genes Regulating Lens Capsule Structure and Stability in Dead Bag Syndrome - Part 1.

Purpose: To investigate potential genetic variants associated with spontaneous Posterior Capsule Rupture (sPCR) in patients diagnosed with Dead Bag Syndrome (DBS).

Setting: Iladevi Cataract and Intraocular Lens (IOL) Research Centre and Raghudeep Eye Hospital, Ahmedabad, Gujarat, India.

Design: Laboratory Study.

Intraoperative Performance and Early Postoperative Outcomes Following Phacoemulsification With Three Fluidic Systems: A Randomized Trial.

Purpose: To compare intraoperative performance and early postoperative outcomes following phacoemulsification with two systems using active fluidics and one using gravity-based fluidics.

Methods: In this prospective randomized trial, 200 eyes were randomized to the traditional and Active Sentry groups (n = 80 eyes each) where the Centurion Vision System was used with traditional or Active Sentry (Alcon Laboratories, Inc) hand-pieces, respectively, or the Infinit group (n = 40 eyes) where the Infiniti Vision System (Alcon Laboratories, Inc) was used. Within the traditional and Active Sentry groups, there were two subgroups with low (30 mm Hg) or high (55 mm Hg) intraocular pressure (IOP) used.

Visual outcomes comparing emmetropia vs mini-monovision after bilateral implantation of a nondiffractive extended vision intraocular lens: randomized trial.

Purpose: To compare visual outcomes and patient satisfaction after bilateral implantation of a nondiffractive extended vision intraocular lens (IOL) when targeting emmetropia vs mini-monovision.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective, randomized controlled trial.

FLACS vs conventional phacoemulsification by junior cataract surgeons: randomized trial.

Purpose: To report intraoperative performance and postoperative outcomes of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification (PE) in the hands of junior surgeons.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, Gujarat, India.

Design: Prospective single-masked randomized controlled trial.

Real-time dynamic changes in intraocular pressure after occlusion break: comparing 2 phacoemulsification systems.

Purpose: To compare real-time intraocular pressure (IOP) response to occlusion break event in 2 phacoemulsification systems.

Setting: Iladevi Cataract and IOL Research Center, India.

Design: Randomized, experimental study.

SINGLE INJECTION RESPONSE TO ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS IN PATIENTS WITH WET AGE-RELATED MACULAR DEGENERATION: Incidence and Characteristics.

Purpose: To determine the incidence of complete resolution of choroidal neovascular membrane-associated exudation with a single antivascular endothelial growth factor injection in treatment-naive wet age-related macular degeneration patients and its associated characteristics.

Methods: Retrospective, observational study of naive wet age-related macular degeneration patients who received antivascular endothelial growth factor therapy with ranibizumab/aflibercept and demonstrated complete resolution of retinal exudation with a single injection. Complete resolution was defined as the total disappearance of the intraretinal fluid, cysts, and subretinal fluid and a return of retinal thickness to <250 μm on spectral-domain optical coherence tomography.

Real-time imaging of airflow patterns and impact of infection control measures in ophthalmic practice: a pandemic perspective.

Purpose: To analyze exhaled airflow patterns in a clinical scenario and the impact of infection control practices and room air circulation in context of the COVID-19 pandemic.

Setting: Raghudeep Eye Hospital, India.

Design: Experimental study.

Comparison of Optical Low-Coherence Reflectometry and Swept-Source OCT-Based Biometry Devices in Dense Cataracts.

Purpose: To investigate agreement between biometric measurements obtained from the Lenstar LS 900 (Haag-Streit AG) based on optical low-coherence reflectometry (OLCR) and the Tomey OA-2000 (Tomey Corporation) based on swept-source optical coherence tomography (SS-OCT) in dense cataracts.

Methods: In this prospective observational study, axial length, keratometry, anterior chamber depth (ACD), lens thickness, and central corneal thickness (CCT) were measured in 124 eyes of 76 patients. Intraocular lens prediction errors and absolute prediction errors were assessed based on postoperative manifest refraction.

Visual outcomes after toric intraocular lens implantation in pediatric eyes undergoing cataract surgery.

Purpose: To evaluate long-term visual outcomes and complications after toric intraocular lens (IOL) implantation in children with preexisting corneal astigmatism undergoing cataract surgery.

Setting: Iladevi Cataract & IOL Research Center, Ahmedabad, India.

Design: Prospective, interventional case series.

Safety and Efficacy of a New Phakic Posterior Chamber IOL for Correction of Myopia: 3 Years of Follow-up.

Purpose: To evaluate the outcomes of a new posterior chamber phakic intraocular lens (IPCL; Care Group, Baroda, India) to correct myopia.

Methods: This prospective, observational case series included 30 eyes undergoing implantation of the IPCL for high myopia (> -8.00 diopters [D]).

Postoperative outcomes of intraocular lens implantation in the bag versus posterior optic capture in pediatric cataract surgery.

Purpose: To compare complications in children up to 4 years old having cataract surgery with intraocular lens (IOL) implantation using 2 techniques: in-the-bag IOL with anterior vitrectomy or optic capture of IOL with no anterior vitrectomy.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective randomized control clinical trial.

Evaluation of uveal and capsule biocompatibility of a single-piece hydrophobic acrylic intraocular lens with ultraviolet-ozone treatment on the posterior surface.

Purpose: To evaluate a single-piece hydrophobic acrylic intraocular lens (IOL) with ultraviolet-ozone (UV-O3) treatment on the posterior surface and compare it with an identical untreated IOL in a rabbit model.

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.

Long-term uveal and capsular biocompatibility of a new accommodating intraocular lens.

Purpose: To evaluate long-term uveal and capsular biocompatibility of a new accommodating intraocular lens (IOL).

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.

Spontaneous bilateral anterior partial in-the-bag intraocular lens dislocation following routine annual eye examination.

Unlabelled: We present the case of an 81-year-old man with pseudoexfoliation syndrome (PXF) in whom spontaneous bilateral anterior partial in-the-bag intraocular lens (IOL) dislocation was diagnosed following a routine dilated examination that demonstrated only mild pseudophacodonesis with no evidence of subluxation. Uneventful cataract surgery with placement of single-piece hydrophobic acrylic posterior chamber IOLs had been performed in both eyes 7 years previously. Bilateral IOL repositioning with scleral fixation was performed to correct the dislocation.

Traumatic dislocation of implanted collamer phakic lens: a case report and review of the literature.

Purpose: Present a case of dislocation of an Implantable Collamer Lens (ICL) that occurs after blunt trauma and review the published literature on this topic.

Methods: Case report and literature review using PubMed.

Results: A 44 year-old male presented to the emergency department with sudden onset of blurry vision after blunt trauma to the left eye.

Outcomes of pediatric cataract surgery in anterior persistent fetal vasculature.

Purpose: To report the intraoperative performance and postoperative outcomes in eyes with anterior persistent fetal vasculature (PFV).

Setting: Iladevi Cataract & IOL Research Centre, India, and Filatov Institute Odessa, Ukraine.

Design: Prospective interventional case series.