Intraoperative performance and long-term postoperative outcomes after scleral fixation of IOLs with polytetrafluoroethylene suture.

Purpose: To report intraoperative performance and long-term postoperative outcomes after scleral fixation of intraocular lenses (IOLs) with polytetrafluoroethylene suture (PTFE).

Setting: Raghudeep Eye Hospital, Ahmedabad, India.

Design: Prospective, interventional case series.

Evaluation of collagen derived antiangiogenic factors and matrix metalloproteinases in anterior lens epithelial cells of pediatric eyes with persistent fetal vasculature.

Purpose: To measure levels of collagen-derived antiangiogenic factors (arresten, canstatin, tumstatin, endostatin) and matrix metalloproteinases (MMP-2 and MMP-9) in anterior lens epithelial cells (LECs) and anterior capsules of children with cataract and persistent fetal vasculature (PFV) as cases and cataract without PFV as controls.

Methods: Anterior capsules harboring LECs were collected from pediatric cataract patients with (n = 13) and without PFV (n = 13) during surgery. Samples were immediately subjected to RNA extraction and cDNA preparation.

Incorporating Optical Coherence Tomography in the Cataract Preoperative Armamentarium: Additional Need or Additional Burden?

Purpose: To determine the usefulness of preoperative optical coherence tomography (OCT) examination to detect asymptomatic macular abnormalities in patients scheduled for cataract surgery.

Methods: Design: Prospective, interventional case series.

Setting: Iladevi Cataract and Visakha Eye Center, Ahmedabad, India.

Comparison of ocular wavefront aberrations in subluxated lenses before and after lens extraction with intraocular lens implantation.

Purpose: To compare the change in ocular higher-order wavefront aberrations (HOAs), visual acuity, and modulation transfer function (MTF) after lens extraction with intraocular lens (IOL) implantation in patients with subluxated lenses.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective case series.

A Prospective Evaluation of Posterior Capsule Opacification in Eyes With Posterior Capsule Plaque-A Case-Control Study.

Purpose: To compare the development of posterior capsule opacification (PCO) between eyes with and without posterior capsule plaque after single-piece hydrophobic acrylic intraocular lens (IOL) implantation 5 years postoperatively.

Design: A prospective observational case-control study.

Methods: One hundred one consecutive eyes with posterior capsule plaque (cases) were compared with the same number of cataractous eyes without posterior capsule plaque (controls).

Long-term postoperative outcomes after bilateral congenital cataract surgery in eyes with microphthalmos.

Purpose: To evaluate the long-term impact of bilateral cataract surgery on postoperative complications, influence of age at surgery on the pattern of axial growth and central corneal thickness (CCT), and visual and orthoptic assessment in microphthalmic eyes.

Setting: Iladevi Cataract and IOL Research Centre, Ahmedabad, India.

Design: Prospective longitudinal study.

Posterior Capsule Opacification After Phacoemulsification: Annual Review.

Purpose: The purpose of this article is to provide a clinical update on posterior capsule opacification (PCO) after phacoemulsification by reviewing the literature from the last 12 months.

Design: This article is a literature review.

Methods: The authors conducted a 1-year literature search in the English language on PCO using PubMed.

The effect of single-piece hydrophobic acrylic intraocular lenses on the development of posterior capsule opacification.

Purpose: To evaluate the long-term effect of a single-piece hydrophobic acrylic intraocular lens (IOL), AcrySof SN60AT (Alcon Laboratories, Fort Worth, Texas, USA), on the development of posterior capsule opacification (PCO) 5 years postoperatively.

Design: Prospective, observational, consecutive, case series.

Methods: setting: Iladevi Cataract and IOL Research Center, Ahmedabad, India.

Long-term longitudinal assessment of postoperative outcomes after congenital cataract surgery in children with congenital rubella syndrome.

Purpose: To assess the intraoperative and long-term longitudinal postoperative outcomes of cataract surgery in children with congenital rubella syndrome.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective observational clinical study.

Real-time dynamic intraocular pressure fluctuations during microcoaxial phacoemulsification using different aspiration flow rates and their impact on early postoperative outcomes: a randomized clinical trial.

Purpose: To compare the impact of varying fluidic parameters on intraoperative intraocular pressure (IOP) fluctuations and postoperative outcomes.

Methods: Prospective randomized study of 80 eyes undergoing cataract surgery that were randomly assigned to low (aspiration flow rate: 20 cc/min; bottle height: 90 cm; vacuum: 400 mm Hg) and high (aspiration flow rate: 40 cc/min; bottle height: 110 cm; vacuum: 400 mm Hg) fluidic parameter groups. Real-time dynamic intraoperative IOP was measured during nuclear fragment removal.

Contrast sensitivity assessment in pediatric cataract surgery: comparison of preoperative and early postoperative outcomes.

Purpose: To evaluate the preoperative and early postoperative differences in contrast sensitivity at high and low spatial frequencies after cataract extraction with in-the-bag intraocular lens (IOL) implantation in children presenting with lamellar and posterior subcapsular cataract.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective clinical trial.

Exploration of molecular factors impairing superoxide dismutase isoforms activity in human senile cataractous lenses.

Purpose: To explore different molecular factors impairing the activities of superoxide dismutase (SOD) isoforms in senile cataractous lenses.

Methods: Enzyme activity of SOD isoforms, levels of their corresponding cofactors copper (Cu), manganese (Mn), zinc (Zn), and expression of mRNA transcripts and proteins were determined in the lenses of human subjects with and without cataract. DNA from lens epithelium (LE) and peripheral blood was isolated.

Histomorphological and immunofluorescence evaluation of clear corneal incisions after microcoaxial phacoemulsification with 2.2 mm and 1.8 mm systems.

Purpose: To compare changes in the incision's histomorphology and denaturation of collagen I in rabbit eyes having microcoaxial phacoemulsification through 2.2 mm and 1.8 mm incision-compatible systems.

Subtle signs of an intact anterior vitreous face during pediatric cataract surgery.

We describe the subtle signs of the anterior vitreous face as a bulging structure, a homogenous staining pattern of 3 buttonholes, and a lamellar or fibrillar pattern intact. This should help surgeons correctly recognize the intact anterior vitreous face.

Corneal endothelial morphologic assessment in pediatric cataract surgery with intraocular lens implantation: a comparison of preoperative and early postoperative specular microscopy.

Purpose: To observe longitudinal changes in the corneal endothelium after pediatric cataract surgery with intraocular lens implantation.

Design: Prospective, longitudinal study.

Methods: settings: Iladevi Cataract and IOL Research Centre, Ahmedabad, India.

Anti-inflammatory effect of low-molecular-weight heparin in pediatric cataract surgery: a randomized clinical trial.

Purpose: To determine if intraocular infusion of low-molecular-weight heparin (enoxaparin) reduces postoperative inflammation in pediatric eyes undergoing cataract surgery with IOL implantation.

Design: Prospective masked randomized controlled trial.

Methods: setting: Private, institutional practice.

Outcomes of pediatric cataract surgery in anterior persistent fetal vasculature.

Purpose: To report the intraoperative performance and postoperative outcomes in eyes with anterior persistent fetal vasculature (PFV).

Setting: Iladevi Cataract & IOL Research Centre, India, and Filatov Institute Odessa, Ukraine.

Design: Prospective interventional case series.

Comparison of the effect of torsional and microburst longitudinal ultrasound on clear corneal incisions during phacoemulsification.

Purpose: To compare incision integrity after clear corneal microcoaxial phacoemulsification using longitudinal and torsional ultrasound (US).

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective randomized experimental clinical trial.

Cionni ring and in-the-bag intraocular lens implantation for subluxated lenses: a prospective case series.

Purpose: To report the intraoperative performance and postoperative outcomes of the Cionni-modified capsule tension ring (CTR) implantation in eyes with subluxated lenses.

Design: Prospective, observational case series.

Methods: This study was carried out at Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Matrix metalloproteinase-2 and -9 activities in the human lens epithelial cells and serum of steroid induced posterior subcapsular cataracts.

Purpose: To evaluate the level of matrix metalloproteinase (MMP)-2 and MMP-9 activities in patients with steroid induced posterior subcapsular cataract (PSC).

Methods: This prospective, observational study comprised of 156 patients having either steroid induced PSC (n=50) or non-steroidal PSC (n=106) were performed to evaluate the level of MMP-2 and MMP-9 activities in the lens epithelial cells (LECs) and the serum. Anterior lens capsules harboring LECs were obtained during phacoemulsification and peripheral blood was collected from patients before administration of anesthesia.

Incidence and influence of posterior capsule striae on the development of posterior capsule opacification after 1-piece hydrophobic acrylic intraocular lens implantation.

Purpose: To determine the incidence of intraoperative posterior capsule striae after implantation of a 1-piece hydrophobic acrylic intraocular lens (IOL), study the clinical impact on the patients' vision, and assess whether the presence of posterior capsule striae increases the risk for posterior capsule opacification (PCO).

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Case-control study.

Rotational stability of a toric intraocular lens: influence of axial length and alignment in the capsular bag.

Purpose: To evaluate the rotational stability of a toric intraocular lens (IOL) using purpose-designed software and to determine the influence of axial length (AL) and in-the-bag IOL alignment on IOL rotation.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective observational case series.

Pars plicata posterior continuous curvilinear capsulorhexis.

We describe a technique of pars plicata manual posterior capsulorhexis performed after implantation of an intraocular lens (IOL) in pediatric cataract surgery. The technique can be used to create a posterior capsulectomy of a desirable size in a controlled manner to avoid destabilization of the IOL. It can be applied selectively in cases of pediatric cataract surgery.

Posterior capsule management in congenital cataract surgery.

Unlabelled: Management of the posterior capsule significantly affects the outcome of pediatric cataract surgery. Posterior capsule opacification (PCO) is rapid and virtually inevitable in very young children when adult-style cataract surgery is performed and the posterior capsule is left intact. In eyes with pediatric cataract, primary posterior capsulotomy and vitrectomy are considered routine surgical steps, especially in younger children.

Posterior capsule opacification in eyes with steroid-induced cataracts: Comparison of early results.

Purpose: To evaluate posterior capsule opacification (PCO) development after cataract surgery in eyes with or without a history of steroid use.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Comparative case series.