Publications by authors named "Satoshi Nagatani"

Background and objectives This study aimed to comprehensively assess degenerative changes in the intervertebral disc, facet joint, and paraspinal muscle after adolescent idiopathic scoliosis surgery and to evaluate clinical outcomes at a five-year follow-up using magnetic resonance imaging (MRI). We hypothesized that the pattern of degeneration would differ based on the distal level of fusion. Materials and methods We retrospectively reviewed patients with adolescent idiopathic scoliosis who underwent surgery between 2006 and 2015.

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Introduction: In high-grade spinal osteotomy involving large anterior column resection, restoration of the structural integrity of the posterior column at the osteotomy site can reduce postoperative instrumentation failure (IF). This study aimed to describe our technique of posterior strut bone grafting using an en bloc resected vertebral arch, which is useful for posterior column reconstruction after high-grade osteotomies during surgeries for spinal tumor and deformity in the lower lumbar spine.

Technical Note: Using a posterior approach, en bloc resection of the targeted vertebral arch was performed in accordance with the surgical technique for total en bloc spondylectomy (TES).

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Complications of compressive spinal cord myelopathy and demyelinating disease can be difficult to diagnose. A 65-year-old woman gradually lost the ability to walk. Her imaging findings showed multiple spinal canal stenosis and ossification of the posterior longitudinal ligament in the cervical and thoracic spine.

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Article Synopsis
  • - The study focuses on the role of the Slc7a5 gene in mice with scoliosis, specifically looking at the impact of selectively inactivating this gene through a conditional knockout approach.
  • - Researchers aimed to determine if the spinal deformities in these mice mirror those seen in pediatric scoliosis, along with investigating the connection between diminished bone mineral density (BMD) and scoliosis development.
  • - Findings indicated that the mice developed scoliosis rapidly during growth, characterized by unique curve patterns and diminished BMD, although reduced BMD did not appear to be a direct cause of the scoliosis progression.
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This study aimed to investigate the clinical outcomes of total en bloc spondylectomy (TES) for spinal metastases previously treated with radiotherapy (RT). This study enrolled 142 patients who were divided into two groups: those with and those without an RT history. Forty-two patients were selected from each group through propensity score matching, and postoperative complications, local recurrence, and overall survival rates were compared.

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Total en bloc spondylectomy (TES) is an effective treatment for spinal tumors. However, its complication rate is high, and the corresponding risk factors remain unclear. This study aimed to clarify the risk factors for postoperative complications after TES, including the patient's general condition, such as frailty and their levels of inflammatory biomarkers.

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Article Synopsis
  • The study examines the effectiveness of total en bloc spondylectomy (TES) in treating isolated spinal metastases from lung cancer in carefully chosen patients.
  • It reviewed data from 14 patients who underwent the procedure, finding a median postoperative survival of 83 months for non-small cell lung carcinoma (NSCLC) cases, with 3-, 5-, and 10-year survival rates at 61.5%, 53.8%, and 15.4%, respectively.
  • The results suggest that TES could be beneficial for patients with controlled primary lung cancer and a good expected postoperative performance status, while prior irradiation to the vertebrae was linked to lower survival rates.
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Introduction: Long-term spinal stability after total en bloc spondylectomy (TES) is challenging. The aim of this study was to examine whether the new method could reduce the incidence of instrumentation failure (IF).

Methods: We retrospectively compared 116 patients with spinal tumors who underwent TES between 2010 and 2019 and were followed up for >1 year.

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Total hip arthroplasty (THA) for patients with hip osteoarthritis improves hip flexion contracture, subsequently improving spinal sagittal balance. However, in some cases, spinal sagittal imbalance develops in the course after THA, and its risk factors remain unknown. We aimed to investigate the risk factors of progressive spinal sagittal imbalance after THA.

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Introduction: Amino acid transporters are transmembrane proteins that are known to mediate the transfer of amino acids. As one of the amino acid transporters, LAT1, which is encoded by Slc7a5, mediates the cellular uptake of the essential amino acids. Recently, most studies have focused on examining the relationship between LAT1 and skeletal formation in terms of development.

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Background: Total en bloc spondylectomy (TES) is one of the surgical procedures which has been recognized as a complete resection for spine tumors. Although the surgery achieves favorable local control for solitary spinal lesion, performing the procedure in the thoracic spine requires circumferential dissection around the vertebral body and bilateral rib resections which might result in decline of pulmonary function postoperatively. This study aimed to clarify whether the number of rib resections negatively impacts pulmonary function after the procedure.

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Potential risk factors associated with future osteoporotic vertebral fracture (OVF) were prospectively investigated in middle-aged and older adult women. We enrolled 197 female patients aged ≥50 years who were scheduled to undergo surgery for lower-extremity degenerative diseases. Patient anthropometric and muscle strength measurements, a bone mineral density measurement of the lumbar spine (L-BMD), and full-spine standing radiographs to examine the presence of old OVFs and spinopelvic sagittal parameters were obtained preoperatively.

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Study Design: Observational study using retrospective contrast-enhanced computed tomography (CT) analysis.

Objective: This study aimed to investigate the anatomical characteristics and variations of the thoracic segmental arteries.

Summary Of Background Data: Few cadaver studies of segmental arteries to the thoracic spine have been reported; however, no previous studies have reported the use of contrast-enhanced CT in the upper to middle thoracic spine.

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The prolonged survival of metastatic cancer patients highlights the importance of the local control of spinal metastases, which reduce patient performance status. This retrospective study examined the medium to long-term outcomes of spinal metastasectomy by evaluating 124 patients who underwent metastasectomy for isolated spinal metastases (2006-2018) with a postoperative follow-up for a minimum of 3 years. The findings present information on patient demographics (i.

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Objective: Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE), is a deleterious complication that can be fatal. However, the prevalence and underlying risk factors for VTE after spinal tumor surgery remain poorly defined.

Methods: Ninety-six patients undergoing spinal tumor surgery with postoperative screening for DVT and PTE were reviewed.

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Study Design: Clinical case series.

Purpose: This study aimed to report dynamization-posterior lumbar interbody fusion (PLIF), our surgical treatment for hemodialysisrelated spondyloarthropathy (HSA), and investigate patients' postoperative course within 2 years.

Overview Of Literature: HSA often requires lumbar fusion surgery.

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