Quality of life post-COVID recovery: A prospective observational study, North India.

Background & objectives The COVID-19 pandemic had a significant impact on global health. While most research has focused on the acute phase, long-term effects on survivors' quality of life (QoL) remain less understood. Persistent symptoms post-recovery highlight a critical gap in understanding the pandemic's impact on survivors.

Exogenous application of salicylic acid and putrescine triggers physiological and biochemical changes in plants to improve growth and bioactive constituents of Ammi majus L.

Ammi majus L. is a rich source of coumarins in addition to various flavonoids, alkaloids, and terpenoids. Medicinal products of Ammi majus seed, with sunlight exposure, are worldwide used for the treatment of vitiligo (pale-white patches on the skin).

Prevalence and patterns of post-COVID-19 symptoms in recovered patients of Delhi, India: a population-based study.

Background: Post-coronavirus disease 2019 (COVID-19) symptoms were widely reported. However, data on post-COVID-19 conditions following infection with the Omicron variant remained scarce. This prospective study was conducted to understand the prevalence, patterns, and duration of symptoms in patients who had recovered from COVID-19.

Alteration of gastric microbiota in Helicobacter pylori - infected individuals suffering from gastroesophageal reflux disease, duodenal ulcer, and gastritis.

Background/aim: Helicobacter pylori ( H. pylori ) colonization affects the gastric microbiome, causing gastrointestinal (GI) diseases. Modern sequencing technology provides insights into GI microbe interaction with H.

Pirh2 modulates the mitochondrial function and cytochrome c-mediated neuronal death during Alzheimer's disease.

Pirh2 is an E3 ubiquitin ligase known to regulate the DNA damage responses through ubiquitylation of various participating signaling factors. DNA damage is a key pathological contributor to Alzheimer's disease (AD), therefore, the role of Pirh2 was investigated in streptozotocin and oligomer Aβ induced rodent experimental model of AD. Pirh2 protein abundance increased during AD conditions, and transient silencing of Pirh2 inhibited the disease-specific pathological markers like level of p-Tau, βamyloid, acetylcholinesterase activity, and neuronal death.

Molecular characterization and phylogenetic analysis of babA gene of Helicobacter pylori isolated from Indian patients with gastrointestinal diseases.

Introduction: Outer membrane protein (OMP) of Helicobacter pylori (H. pylori) i.e.

Content-based image retrieval of Indian traditional textile motifs using deep feature fusion.

In the fast-paced fashion world, unique designs are like early birds, grabbing attention as online shopping surges. Fabric texture plays an immense role in selecting the perfect design. Indian Traditional textile motifs are pivotal, showing rich cultural origins and attracting worldwide art fanatics.

Enhancing growth, vitality, and aromatic richness: unveiling the dual magic of silicon dioxide and titanium dioxide nanoparticles in L.

, commonly known as "Holy basil," is renowned for its notable medicinal and aromatic attributes. Its unique fragrance attributes to specific volatile phytochemicals, primarily belonging to terpenoid and/or phenylpropanoid classes, found within their essential oils. The use of nanoparticles (NPs) in agriculture has attracted attention among plant researchers.

The use of Mycobacterium tuberculosis H37Ra-infected immunocompetent mice as an in vivo model of persisters.

Persistence of Mycobacterium tuberculosis (Mtb) is one of the challenges to successful treatment of tuberculosis (TB). In vitro models of non-replicating Mtb are used to test the efficacy of new molecules against Mtb persisters. The H37Ra strain is attenuated for growth in macrophages and mice.

COVID-19 vaccination: Immune response in healthcare workers-A study with review of literature.

Background: As the world has been going through a pandemic of coronavirus disease 2019 (COVID-19) for the past two years, a safe and effective vaccine was urgently needed. Vaccination against the disease was launched in India on January 16, 2021 with healthcare workers, frontline workers, and the elderly above 60 years being the first beneficiaries. Vaccines being used in India are Covishield and Covaxin.

Combined application of SiO and TiO nanoparticles enhances growth characters, physiological attributes and essential oil production of Benth.

Nanoparticles (NPs) have gained considerable interest among researchers in the field of plant biology, particularly in the agricultural sector. Among the numerous NPs, the individual application of silicon (Si) or titanium (Ti), in their oxide forms, had a positive influence on growth, physiochemical and yield attributes of plants. However, the synergetic application of both these NPs has not been studied yet.

Pirh2 modulates amyloid-β aggregation through the regulation of glucose-regulated protein 78 and chaperone-mediated signaling.

Amyloid-β (Aβ) protein aggregation in the brain is a pathological hallmark of Alzheimer's disease (AD) however, the underlying molecular mechanisms regulating amyloid aggregation are not well understood. Here, we studied the propitious role of E3 ubiquitin ligase Pirh2 in Aβ protein aggregation in view of its regulatory ligase activity in the ubiquitin-proteasome system employing both cellular and sporadic rodent models of AD. Pirh2 protein abundance was significantly increased during Streptozotocin (STZ) induced AD conditions, and transient silencing of Pirh2 significantly inhibited the Aβ aggregation and modified the dendrite morphology along with the substantial decrease in choline level in the differentiated neurons.

Composition Dependent Strain Engineering of Lead-Free Halide Double Perovskite: Computational Insights.

The critical photophysical properties of lead-free halide double perovskites (HDPs) must be substantially improved for various applications. In this regard, strain engineering is a powerful tool for enhancing optoelectronic performance with precise control. Here, we employ simulations to investigate the impact of mild compressive and tensile strains on the photophysics of CsAgB'X (B' = Sb, Bi; X = Cl, Br) perovskites.

Assessment of the low-field magnetic resonance imaging for the brain scan imaging of the infant hydrocephalus.

Objective: In today's global clinical settings, low-field magnetic resonance imaging (MRI) technology is becoming increasingly prevalent. Ensuring high-quality image acquisition is crucial for accurate disease diagnosis and treatment and for evaluating the impact of poor-quality images. In this study, we explored the potential of deep learning as a diagnostic tool for improving image quality in hydrocephalus analysis planning.

Plant-derived smoke water and karrikinolide (KAR) enhance physiological activities, essential oil yield and bioactive constituents of L.

Introduction: The current study was carried out with the hypothesis that foliar application of plant-derived smoke water (PDSW) and karrikinolide (KAR) might enhanced the plant growth, physiology, and essential oil production of the L. Karrikinolide (KAR) is one of the most important bioactive constituents of PDSW.

Methods: Mint ( L.

Disturb mitochondrial associated proteostasis: Neurodegeneration and imperfect ageing.

The disturbance in mitochondrial functions and homeostasis are the major features of neuron degenerative conditions, like Parkinson's disease, Amyotrophic Lateral Sclerosis, and Alzheimer's disease, along with protein misfolding. The aberrantly folded proteins are known to link with impaired mitochondrial pathways, further contributing to disease pathogenesis. Despite their central significance, the implications of mitochondrial homeostasis disruption on other organelles and cellular processes remain insufficiently explored.