Green-synthesized silver nanoparticles from incensole acetate modulate expression in DMBA-induced breast cancer.

As natural chemicals may have fewer side effects than conventional medicines, their usage in cancer treatment is becoming more popular. Nanoformulations have been the focus of recent developments to increase the anticancer potential of phytocompounds or pure isolated components. To evaluate the anticancer potential of silver nitrate nanoparticles (AgNPs), essential oil (EO) from was extracted, a terpene compound was isolated and incensole acetate (IA)-mediated silver nanoparticles (IA-AgNPs) were synthesized.

Emerging trends and future challenges of advanced 2D nanomaterials for combating bacterial resistance.

The number of multi-drug-resistant bacteria has increased over the last few decades, which has caused a detrimental impact on public health worldwide. In resolving antibiotic resistance development among different bacterial communities, new antimicrobial agents and nanoparticle-based strategies need to be designed foreseeing the slow discovery of new functioning antibiotics. Advanced research studies have revealed the significant disinfection potential of two-dimensional nanomaterials (2D NMs) to be severed as effective antibacterial agents due to their unique physicochemical properties.

Multifunctional nucleoside-AIEgens bearing quaternary ammonium cationic for reversible response, bioimaging, and antibacterial.

A multifunctional nucleoside-based AIEgens sensor (TPEPy-dU) was constructed for visual screening of Hg, determine to the reversible response of Fe and biothiols, and applied for cell imaging, and drug-free bacterial killing. The TPEPy-dU displayed 10-folds fluorescence enhancement at 540 nm of emission in response to trace Hg ions with 10 nM of LOD, which can be immediately quenched by adding Fe or GSH/Cys-containing sulfhydryl groups. Moreover, their bacterial staining efficiency closely correlates with their antibacterial efficacy as they demonstrated comparatively higher antibacterial activity against Gram-positive bacteria than Gram-negative bacteria.

Copper-based nanoparticles against microbial infections.

Drug-resistant bacteria and highly infectious viruses are among the major global threats affecting the human health. There is an immediate need for novel strategies to tackle this challenge. Copper-based nanoparticles (CBNPs) have exhibited a broad antimicrobial capacity and are receiving increasing attention in this context.

Defect-rich graphene-coated metamaterial device for pesticide sensing in rice.

Performing sensitive and selective detection in a mixture is challenging for terahertz (THz) sensors. In light of this, many methods have been developed to detect molecules in complex samples using THz technology. Here we demonstrate a defect-rich monolayer graphene-coated metamaterial operating in the THz regime for pesticide sensing in a mixture through strong local interactions between graphene and external molecules.

Induced Autophagy of Macrophages and the Regulation of Inflammatory Effects by Perovskite Nanomaterial LaNiO.

Perovskite nanomaterials (NMs) possess excellent physicochemical properties and have promising applications in light-emitting diodes (LEDs), lasers, photodetectors, and artificial synapse electronics. Potential exposure to these NMs happens in the manufacture and application of the perovskite-based products, however, the biological safety of these NMs is still unknown. Here, we used the LaNiO NM (LNO), a typical kind of perovskite nanostructures to study the interaction with macrophages (J774A.

Large scale assembly of nanomaterials: mechanisms and applications.

The large scale assembly of nanomaterials is the crucial factor contributing to the creation of high-performance devices based on nanotechnology, which have flourished in an unprecedented manner. In this review, we summarize the main methods for the large-scale integration of nanomaterials, including the bubble blown assembly, capillary-force-assisted assembly, electric-field-assisted assembly, and Langmuir-Blodgett assembly. Assembly principles and general procedures of these methods are described in detail.

Shape-dependent significant physical mutilation and antibacterial mechanisms of gold nanoparticles against foodborne bacterial pathogens (Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus) at lower concentrations.

Gold nanoparticles (AuNPs) have been reported for their most desirable properties as compared to any other noble metal-based nanoparticles, which wider their applications in various fields including catalysis, bio-imaging, biosensors, medicine, biology, and material chemistry. In this study, the shape-dependent antibacterial activity of AuNPs: nanospheres (AuNSps), nanostars (AuNSts), and nanocubes (AuNCs) were investigated against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus at lower concentrations. The optical, crystallographic and morphological characterization of AuNPs was analyzed by UV-visible spectroscopy, X-ray diffraction spectroscopy, and transmission electron microscopy (TEM).

Temperature-dependent terahertz vibrational spectra of tetracycline and its degradation products.

Terahertz (THz) spectroscopy has emerged as an attractive technique for qualitative and quantitative detection. Analysis of these chemicals in the THz range under various temperatures can yield detailed information on molecular vibrational modes, which is of utmost importance for effective detection. Here we report the use of THz time-domain spectroscopy (THz-TDS) to measure tetracyclines hydrochloride (TCH) and its degradation products including epitetracycline hydrochloride (ETCH), anhydrotetracycline hydrochloride (ATCH), and epianhydrotetracycline hydrochloride (EATCH) over the temperature range of 4.

Characterization of an A-kinase anchor protein in equine spermatozoa and examination of the effect of semen cooling and cryopreservation on the binding of that protein to the regulatory subunit of protein kinase-A.

Objective: To determine whether a homologue of A-kinase anchor protein 4 (AKAP4) is present and functional as an AKAP in equine spermatozoa and examine the effect of semen cooling and cryopreservation on binding of equine AKAP4 to the regulatory (RII) subunit of protein kinase-A (PK-A).

Sample Population: Ejaculated semen collected from 2 fertile stallions, 3 bulls, and 3 humans.

Procedure: Identification of an equine homologue of AKAP4 was investigated via DNA sequencing.

Differential ubiquitination of stallion sperm proteins: possible implications for infertility and reproductive seasonality.

Antibodies against ubiquitin, a universal proteolytic marker, show increased cross-reactivity with defective spermatozoa in men and bulls. We investigated sperm ubiquitination in the stallion, a seasonally polyestrous mammal. Immunofluorescence and immunoelectron microscopy demonstrated that anti-ubiquitin antibodies bind to the surface of both membrane-intact and aldehyde-fixed spermatozoa.