Publications by authors named "Sabariswaran Kandasamy"

Chromium (Cr) contamination in agricultural soil poses a significant threat to crop productivity and human health. However, strategies to reduce Cr bioavailability and transfer within the soil-plant system remain limited. The sole application of biochar or Thiourea has been reported to mitigate Cr-induced toxicity in plants.

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Hydrogen, a carbon-free fuel, has the potential to aid global nations in achieving eight of the 17 Sustainable Development Goals (SDG). The shortcomings associated with H transportation and storage can be mitigated by using NH as hydrogen carrier because of its better safety, physical, and environmental properties. However, to achieve the global climate target, green ammonia production must be incremented by four times (688 MT) from the current level.

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The imine base and Cu precursors were combined using magnetic stirring to formulate the Cu complexes. The formation of the imine base was confirmed by electronic and vibrational spectra, proton NMR, LC-mass spectrometry, and computational studies, which also optimized the final structure. The Cu complexes were characterized using electronic and vibrational spectra, magnetic susceptibility, molar conductivity, a variable temperature magnetometer, and ESR spectroscopy.

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Various bodily functions are maintained, and health benefits are provided by food-derived bioactive components. Fruits and vegetables contain numerous beneficial components, including vitamins, minerals, antioxidants, enzymes, and phytonutrients. However, the body's ability to absorb these substances at a given rate and degree frequently limits their bioavailability.

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Future agricultural practices necessitate green alternatives to replace hazardous insecticides while distinguishing between pests and beneficial insects. Chitosan, as a biological macromolecule derived from chitin, is biodegradable and exhibits low toxicity to non-target organisms, making it a sustainable alternative to synthetic pesticides. This review identifies chitosan-derivatives for insecticidal activity and highlights its efficacy including genotoxicity, defense mechanism, and disruption of insect's exoskeleton at different concentrations against several insect pests.

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Three-dimensional printing is one of the emerging technologies that is gaining interest from the pharmaceutical industry as it provides an opportunity to customize drugs according to each patient's needs. Combining different active pharmaceutical ingredients, using different geometries, and providing sustained release enhances the effectiveness of medicine. One of the most innovative uses of 3D printing is producing fabrics, medical devices, medical implants, orthoses, and prostheses.

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Heavy metals pose a serious global threat to the environment. Hence, removing hazardous metals from soil samples has become complicated over the past few years. The current work looked into the remediation of heavy metals from aqueous solutions using a bacterial community and a unique bacterium obtained from metal-contaminated soil.

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The escalating use of pesticides in agriculture for enhanced crop productivity threatens aquatic ecosystems, jeopardizing environmental integrity and human well-being. Pesticides infiltrate water bodies through runoff, chemical spills, and leachate, adversely affecting algae, vital primary producers in marine ecosystems. The repercussions cascade through higher trophic levels, underscoring the need for a comprehensive understanding of the interplay between pesticides, algae, and the broader ecosystem.

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Wildfires have complex impacts on forests, including changes in vegetation, threats to biodiversity, and emissions of greenhouse gases like carbon dioxide, which exacerbate climate change. The influence of wildfires on animal habitats is particularly noteworthy, as they can lead to significant changes in native environments. The extent of these alterations in species and habitats plays a crucial role in shaping forest ecology.

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Insecticides are indispensable for modern agriculture to ensuring crop protection and optimal yields. However, their excessive use raises concerns regarding their adverse effects on agriculture and the environment. This study examines the impacts of insecticides on agriculture and proposes remediation strategies.

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The Pharmaceuticals and Personal Care Products (PPCPs) presence at harmful levels has been identified in aquatic ecosystems all over the world. Currently, PPCPs are more common in aquatic regions and have been discovered to be extremely harmful to aquatic creatures. Waste-water treatment facilities are the primary cause of PPCPs pollution in aquatic systems due to their limited treatment as well as the following the release of PPCPs.

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Polycyclic aromatic hydrocarbons (PAHs) are distributed worldwide due to long-term anthropogenic pollution sources. PAHs are recalcitrant and highly persistent in the environment due to their inherent properties, such as heterocyclic aromatic ring structures, thermostability, and hydrophobicity. They are highly toxic, carcinogenic, immunotoxic, teratogenic, and mutagenic to various life systems.

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This study was designed to appraise the antioxidant and anticancer competence of solvent extracts of Tecoma stans (Linn) and analyze the phytoligands interaction against Bcl 2 VEGFR2 through in silico studies. The phytochemical analysis revealed that the ethyl acetate extract contains more number of pharmaceutically valuable phytochemicals than other solvent extracts. Among the various phytochemicals, flavonoid was found as a predominant component, and UV-Vis- spectrophotometer analysis initially confirmed it.

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The goal of this study was to extract saponins from the tuberous root of Decalepis hamiltonii and assess their potential clinical applications, which included antioxidant, antibacterial, antithrombotic, and anticancer properties. Surprisingly, the results of this study revealed that the extracted saponins have excellent antioxidant activities, as demonstrated by 2,2-diphenylpicrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), Hydrogen peroxide (HO), and Nitric oxide (NO) scavenging assays. Nonetheless, at a concentration of 100 g/mL, crude saponin had excellent antibacterial activity, particularly against gramme positive bacteria (Staphylococcus aureus, Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus), followed by gramme negative bacteria (Escherichia coli, Salmonella typhi, Proteus mirabilis, and Klebsiella pneumonia).

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A sequence of Schiff base Cobalt (II) Mobile Composite Matter 41 heterojunction (SBCo(II)-MCM 41) was prepared by post-synthetic protocols. Various characterization techniques were used to characterize the above samples and MCM 41: Morphology, functional groups, optical properties, crystalline nature, pore diameter, and binding energy by scanning electron microscope (SEM), High-resolution transition electron microscopy (HR-TEM), Fourier transform infrared spectroscopy (FTIR), Ultra Violet-Visible Spectroscopy (UV), X-ray powder diffraction (XRD), Brunauer-Emmett-Teller (BET) and X-ray Photoelectron Spectroscopy (XPS). After the encapsulation of SBCo(II) on the MCM 41, the intensity in the 100-plane in powder x-ray diffraction (XRD) decreased significantly; moreover, the light absorption behavior in UV analysis was improved.

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Oral cancer is a significant non-communicable disease affecting both emergent nations and developed countries. Squamous cell carcinoma of the head and neck represent the eight major familiar cancer types worldwide, accounting for more than 350,000 established cases every year. Oral cancer is one of the most exigent tumors to control and treat.

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In recent history, immunotherapy has become a viable cancer therapeutic option. However, over many years, its tenets have changed, and it now comprises a range of cancer-focused immunotherapies. Clinical trials are currently looking into monotherapies or combinations of medicines that include immune checkpoint inhibitors (ICI), CART cells, DNA vaccines targeting viruses, and adoptive cellular therapy.

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In most developing countries, the availability of drinking water is a major problem. This creates the need for treatment of wastewater, reusability of water, etc. The membrane technology has its place in the market for treating such water.

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The ever-increasing rate of pollution has attracted considerable interest in research. Several anthropogenic activities have diminished soil, air, and water quality and have led to complex chemical pollutants. This review aims to provide a clear idea about the latest and most prevalent pollutants such as heavy metals, PAHs, pesticides, hydrocarbons, and pharmaceuticals-their occurrence in various complex mixtures and how several environmental factors influence their interaction.

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Contamination of aquatic systems with pharmaceuticals, personal care products, steroid hormones, and agrochemicals has been an immense problem for the earth's ecosystem and health impacts. The environmental issues of well-known persistence pollutants, their metabolites, and other micro-pollutants in diverse aquatic systems around the world were collated and exposed in this review assessment. Waste Water Treatment Plant (WWTP) influents and effluents, as well as industrial, hospital, and residential effluents, include detectable concentrations of known and undiscovered persistence pollutants and metabolites.

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Article Synopsis
  • Environmental toxicity from antimony (Sb) is increasing due to industrial use, posing risks to ecosystems and human health, while traditional remediation methods can cause further pollution.
  • This research investigates a bio-electrochemical system using a microbial fuel cell (MFC) and sulfate-reducing bacteria (SRB) to effectively reduce toxic Sb levels while generating electricity.
  • Results showed high efficiency in sulfate reduction and antimony removal, confirming the potential of the MFC-SR10 approach for combined wastewater treatment and energy production.
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Plant development processes are regulated by epigenetic alterations that shape nuclear structure, gene expression, and phenotypic plasticity; these alterations can provide the plant with protection from environmental stresses. During plant growth and development, these processes play a significant role in regulating gene expression to remodel chromatin structure. These epigenetic alterations are mainly regulated by transposable elements (TEs) whose abundance in plant genomes results in their interaction with genomes.

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Fatty liver disease (FLD) is one of the largest burdens to human health worldwide and is associated with gut microbiome and metabolite stability. Engineered liver tissues have shown promise in restoring liver functions in non-alcoholic FLD (NAFLD), hepatitis and cirrhosis. Fatty liver, largely noted in obesity and hepatic cancer, is highly fatal and has led to a global increase in death rates.

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