Can Glycerol Be Used as an Effective Alternative Storage Medium for Avulsed Teeth Before Replantation?

Introduction For successful replantation of avulsed teeth, preserving the vitality of periodontal ligament (PDL) cells of the avulsed tooth is important. The aim of the present study was to evaluate the usage of glycerol by comparing its different concentrations with the gold standard medium, i.e.

Utilization of Biospecimens as a Biobank Output for Biomedical Research-A Report from the ISBER Annual Meeting 2024 Annual Meeting Roundtable Discussions.

Despite widespread recognition of the need to increase sample utilization, the utilization rate of collected biospecimens for research is still low. In recent years, funders have shifted priorities towards supporting biobanks/collections with high utilization. Given the imperative to upscale sample utilization, a roundtable was held to discuss the considerations for maximizing and measuring the utilization of biospecimens and the output models that biobanks can employ to ensure greater impact and directly attributable advancements in medical science.

Vitamin - D supplements for better osteointegration in dental implant surgery: A randomized control trial.

The role of Vitamin - D in osseointegration is of interest. Henceforth, the randomized control trial was conducted wherein 40 Participants were equally divided into two groups. Group A received Vitamin - D3 for 12 weeks following implant placement while Group B, did not receive Vitamin - D supplementation.

Sperm Histone Mediated Epigenetic Inheritance†.

During spermatogenesis, majority of the histones are replaced by protamines to enable the compaction of the sperm chromatin for efficient delivery into the oocyte. Even after the gross histone replacement, some histones are retained in the sperm ranging from 1-15% across mammalian species. The post-translational modifications (PTMs), present on the retained histones of the sperm regulate the embryonic development, post fertilization, making them the suitable candidate for paternal epigenetic inheritance.

Microbial indoor air pollution in Delhi Metropolitan City is attributable to severe respiratory and general health effects among residents.

Indoor air quality plays a crucial role in the health and well-being of residents. Delhi, known as one of the most polluted cities globally, often receives insufficient attention in managing and mitigating related health impacts. This study isolated, characterized, and assessed microbial indoor air quality (bioaerosols) using multiproxy approaches and correlated findings with associated health effects.

A rare and first report of Ochrobactrum intermedium co-infection in coxsackievirus-A24-infected acute hemorrhagic conjunctivitis patients.

Epidemic form of acute hemorrhagic conjunctivitis was reported from different geographical locations of the world, during 2023. Since the viral agents are well established behind acute hemorrhagic conjunctivitis outbreaks, this study aims to investigate the bacterial agent associated with the acute hemorrhagic conjunctivitis outbreak that occurred in the eastern Uttar Pradesh region of India. The bacterial infection was investigated in 91 conjunctival swabs collected from acute hemorrhagic conjunctivitis patients during the outbreak.

Sustainable Biotransformation of Food Waste into Biogas Via Microbial Anaerobic Digestion: A Review.

Unlabelled: The continuous rising volume of solid waste and depletion of conventional energy reserves are important global challenges which humanity faces in twenty-first century. Food waste (FW) constitutes major (organic) fraction of solid waste in the developing nations. Therefore, the segregation of food waste and its utilization for the generation of biogas through anaerobic digestion (AD) could provide a viable solution for the global challenges.

Valorization of Coconut Shell and Blue Berries Seed Waste into Enhance Bacterial Enzyme Production: Co-fermentation and Co-cultivation Strategies.

Broad industrial application makes cellulolytic enzymes always in industrial demand with economic and sustainable production method. Production of cellulase enzymes via solid state fermentation mode using solid waste can resolve enzyme production and solid waste management issue in eco-friendly way. In present investigation, co-fermentation of solid wastes and microbial co-cultivation using potential cellulase producers strains have been applied as promising strategy for enhancement of cellulase at economical scale.

Marine Microbial Bioremediation of Heavy Metal Contaminants in Waste Water for Health and Environmental Sustainability: A Review.

Heavy metal pollution is result of large-scale industrialization and continuous anthropogenic activities which lead to cause severe environmental concern. Marine pollution is on rapid progress in recent years due to release of heavy toxicity induced by heavy metal pollutants and has become serious global threat for environmental security reasons. Bioremediation of marine heavy metal pollutants via marine microbial diversity is one of the most sustainable, adaptable and promising approach.

Sustainable Fabrication of Graphene Quantum Dots Preparation From Cellulosic Carbon Waste for Application in Photoinduced Biohydrogen Production.

Graphene quantum dots (GQDs) are a novel carbon nanomaterial from the graphene class, known for their unique physicochemical properties and diverse range of applications. However, toward the sustainable application of GQDs, their synthesis methods remain the main roadblock due to high production costs and the release of toxic byproducts. For this reason, developing sustainable and economical fabrication methods for GQDs remains one of the most pressing and promising areas of research.

Impact of mouthguards on the prevention of dentofacial injuries and sports performance among athletes: An umbrella review.

Does the use of mouthguards (MGs) effectively prevent dentofacial injuries in athletes? Research Protocol: An umbrella review of systematic reviews (SRs) with or without meta-analyses was conducted. The study followed the Preferred Reporting Items for Overviews of Reviews guidelines, and the AMSTAR 2 tool was used for methodological quality assessment. A comprehensive search was conducted across MEDLINE, EMBASE, CINAHL, Scopus, Web of Science, Cochrane Library, and gray literature sources.

Mandibular anterior hypo-hyperdontia: a rare mixed dentition anomaly.

Hypo-hyperdontia, the simultaneous occurrence of hypodontia and hyperdontia, is a rare dental anomaly, especially in the mandibular anterior region. This case report presents a male patient with unilateral agenesis of the mandibular central incisor (41) and the presence of mesiodens. Clinical and radiographic evaluation confirmed the diagnosis.

A Case Report on the Diagnosis and Management of a Rare Ameloblastic Fibro-Odontoma in the Anterior Maxilla of a Pediatric Patient.

Ameloblastic fibro-odontoma (AFO) is an uncommon, non-cancerous odontogenic tumor that predominantly affects children and young adolescents. This case report details a nine-year-old male patient who presented with a firm swelling accompanied by intermittent serous discharge in the upper right jaw following a fall. Clinical assessment revealed incomplete mouth closure, facial asymmetry, and dentoalveolar extrusion.

ORIF (Open Reduction and Internal Fixation) of the Zygomatic Arch Fracture Using Transbuccal Instrumentation.

Background: The zygomatic arch fracture indicated using ORIF (open reduction and internal fixation) after its fracture in a few clinical scenarios.

Aim: To assess the efficacy of ORIF (open reduction and internal fixation) for zygomatic arch fracture using transbuccal instrumentation.

Method: The study assessed 60 subjects who needed ORIF of the zygomatic arch fracture, and reduction was done following transbuccal instrumentation under general anesthesia.

Mapping of deep pool habitats in the rivers of water deficit Bundelkhand region: a novel approach for fish conservation and sustainable management.

Deep pools are perennial habitats in riverine systems that serve as feeding and breeding grounds for diverse aquatic biota, including threatened and endemic fishes. Mapping and understanding the dynamics of deep pools are vital for conservation planning and management, especially in water deficit ecoregions. This study was conducted to assess the temporal trend in the climatic variables and map deep pools in four rivers, viz.

Description of a new troglophilic loach, Schistura densiclava (Teleostei: Nemacheilidae) from Meghalaya, northeast India.

Integrative taxonomy reveals a new troglophilic species of Schistura, from a cave-dwelling population inhabiting stream draining (Barak-Surma-Meghna drainage) through the Krem (=cave) Mawjymbuin in East Khasi Hills of Meghalaya. Morphologically, the new species is easily distinguished from its congeners in having a combination of characters, including a unique colour pattern in the form of 14-20 greyish black to faint black bars overimposed to a black midlateral stripe on a greyish brown to pale beige (yellowish green in life); pre-dorsal bars thin, numerous, wider than interspaces, weakly contrasted, sometimes broken and/or incomplete; bars posterior of anal-fin base numerous and variable, mostly broken or incomplete, located on lower flank, weakly contrasted; a complete lateral line; presence of an axillary pelvic lobe; an uninterrupted thick black stripe along the base of the dorsal fin; an incomplete black basicaudal bar, dissociated, occupying median one-third of caudal-fin base; conspicuous black botch on the procurrent rays of the upper lobe of the caudal fin; and a type of sexual dimorphism: males with slender body, bars mostly irregular on flanks and slightly puffy cheek with greater lateral head length; females with regular-shaped bars and swollen body. Analysis of the mitochondrial cytochrome c oxidase I (COI) gene sequence of the new species shows significant genetic divergence with p distances ranging 4.

Nanofabrication of Biochar from Cellulosic Waste for Bio-Sensing Application of Waste Water Treatment: Process, Challenges and Future Update.

Unlabelled: Waste water pollution is one of the most prominent concerns across the globe due to its severe impact on human health and environment which affects the ecosystem directly. Therefore, for sustainable and consistence environment, waste water treatment is the primary and mandatory agenda of agencies involve worldwide to rectify this issue. Additionally, among various sustainable trail based strategies for waste water treatment, biochar catalyst utilization is very potential and impactful whereas, use of nanoform of biochar which is also known as nanobiochar is more impactful in waste water pollution remediation.

Gut Microbial Metabolite 4-Ethylphenylsulfate Is Selectively Deleterious and Anticancer to Colon Cancer Cells.

Gut microbiota-derived metabolites have emerged as promising candidates in cancer therapeutics. Among these metabolites, 4-ethylphenyl sulfate (4-EPS), produced through dietary metabolism, is linked to chronic diseases but remains unexplored as a therapeutic agent for colorectal cancer (CRC) treatment. This study investigates the selective anticancer activity of 4-EPS using HCT-116 human colorectal adenocarcinoma cells and CCD 841 normal colon epithelial cells.

Sensitive and rapid visual detection of Orientia tsutsugamushi with Recombinase assisted dipstick detection platform.

Orientia tsutsugamushi, the causative agent of scrub typhus, poses a global threat, particularly in rural areas where standard PCR methods are impractical. To enable timely management of scrub typhus, we developed a rapid, simple, sensitive, and specific molecular detection method suitable for low-resource settings with minimal instrumentation. The developed platform enabled rapid detection of OT (≤25 minutes).

Epidemiology of acute undifferentiated febrile illness and acute encephalitis syndrome cases in Northern India: a prospective observational study.

Purpose: Acute undifferentiated febrile illness (AUFI) and acute encephalitis syndrome (AES) continue to be major public health concerns, particularly in rural areas with limited healthcare facility. We investigated the aetiological agents responsible for seasonal sporadic AUFI and AES cases in Northern India.

Method: The study included 4200 patient samples (April 2022 to March 2024), fulfilling the AUFI or AES case definition.

An update on CAD-CAM usage for removable partial denture fabrication: A systematic review.

The accuracy of Computer-Aided Design and Computer-Aided Manufacturing (CAD-CAM) systems in the fabrication of removable partial denture (RPD) frameworks compared to conventional manufacturing methods is of interest to dentists. Known data show that CAD-CAM systems produce RPD frameworks with superior fit and adaptation, potentially reducing post-insertion adjustments and enhancing patient satisfaction. The importance of digital impressions, advanced CAD software and the capabilities of milling or 3D printing equipment in determining the success of CAD-CAM fabricated frameworks is highlighted.

Unravelling reproductive biology of the striped gourami, Trichogaster fasciata (Bloch and Schneider, 1801) with reference to climate change and implications on breeding phenology in Ganges basin, India.

The present study explores the reproductive characteristics and breeding phenology of striped gourami, Trichogaster fasciata from river Gomti, a tributary of river Ganges, India in relation to eco-climatic variables. The calculated size at sexual maturity (Lm) is approximately 5.2 cm.

Evaluation of a Novel Distraction Method in Paediatric Dental Patients: An Observer-Blinded, Randomised, Parallel-Group, Superiority Clinical Trial.

Background: The study introduces novel camouflage sleeves for the 'Dental Syringe Camouflage Technique' (DSCT) as a distraction tool to reduce dental anxiety and pain in paediatric patients while evaluating its efficacy.

Aim: To evaluate the efficacy of DSCT using light-/dark-coloured sleeves to reduce needle-associated anxiety and pain in paediatric dental patients.

Design: A single-blinded, randomized clinical trial with 76 children aged 6-9 years, divided into control and experimental groups.

Goldenhar Syndrome and Its Clinical Manifestation With Dentofacial Considerations: A Case Report.

Goldenhar syndrome, a variant of hemifacial microsomia, is a rare congenital condition characterized by mandibular hypoplasia, epibulbar dermoids, preauricular tags, and vertebral anomalies. This article discusses the case of a young boy presenting with classical signs of Goldenhar syndrome along with bilateral mandibular second premolar (BMSP) agenesis. While this syndrome can lead to significant physical and functional difficulties, timely recognition and tailored management are pivotal in enhancing the patient's quality of life and long-term health outcomes.

RT-RPA Assisted CRISPR/Cas12a Based One-Pot Rapid and Visual Detection of the Pan-Dengue Virus.

Globally ≤ 4 billion of the population are at potential risk of contracting dengue virus (DENV) infection. Seasonal outbreaks of dengue are frequently reported causing a high healthcare burden. Undiagnosed DENV can lead to severe morbidity and mortality.