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The accuracy of Computer-Aided Design and Computer-Aided Manufacturing (CAD-CAM) systems in the fabrication of removable partial denture (RPD) frameworks compared to conventional manufacturing methods is of interest to dentists. Known data show that CAD-CAM systems produce RPD frameworks with superior fit and adaptation, potentially reducing post-insertion adjustments and enhancing patient satisfaction. The importance of digital impressions, advanced CAD software and the capabilities of milling or 3D printing equipment in determining the success of CAD-CAM fabricated frameworks is highlighted. Despite promising results, further research is needed to evaluate the long-term clinical performance of CAD-CAM systems in RPD fabrication and to address the existing limitations.
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http://dx.doi.org/10.6026/9732063002001794 | DOI Listing |
Med Eng Phys
October 2025
Department of Engineering Science, University of Oxford, United Kingdom. Electronic address:
Traditionally, clinical devices are designed, tested and improved through lengthy and expensive laboratory experiments and clinical trials [1]. More recently, computational methods have allowed for rapid testing, speeding up the design process and enabling far more complete searches of design space. While computational models cannot fully capture the complexities of biological systems, they provide valuable insights into crucial underlying mechanisms, such as the effects of fluid-structure interactions (FSIs).
View Article and Find Full Text PDFBioinspir Biomim
September 2025
Mechanical Intelligence (MI) Research Group, London South Bank University, 103 Borough Road, London, London, SE1 0AA, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Conventional rigid grippers remain the most-used robotic grippers in industrial assembly tasks. However, they are limited in their ability to handle a diverse range of objects. This study draws inspiration from nature to address these limitations, employing multidisciplinary methods, such as computer-aided design, parametric modeling, finite element analysis, 3D printing, and mechanical testing.
View Article and Find Full Text PDFJ Adv Prosthodont
August 2025
Department of Statistical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Purpose: This study aims to compare the occlusal trueness and precision of teeth manufactured using two modern digital milling processes.
Materials And Methods: A total of 38 complete dentures (CDs) were fabricated and analyzed. CDs in Group 1 (monolithic) (n = 19) were produced using a monolithic bicolor resin disk, whereas in Group 2 (oversize) (n = 19) were fabricated using the oversize process, which involves two separate resin disks of different colors.
Carbohydr Polym
November 2025
Department of Pharmacy - Pharmaceutical Sciences, University of Bari Aldo Moro, E. Orabona St., 70125 Bari, Italy.
Direct printing of pharmaceutical powders allows the creation of personalized paediatric dosage forms, such as orodispersible films (ODFs). In this study, we present an optimized protocol to prepare midazolam (MDZ)/γ-cyclodextrin (γ-CD) inclusion complex-loaded ODFs using the innovative direct powder extrusion 3D printing technique (DPE). ODFs were formulated with a polymer blend consisting of polyethylene oxide and hydroxypropyl methylcellulose, in the presence or without γ-CD.
View Article and Find Full Text PDFJ Esthet Restor Dent
September 2025
Department of Restorative Dentistry, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.
Objective: To investigate the effect of deep margin elevation (DME) on the fracture resistance and fracture patterns of various indirect resin-based composite materials.
Materials And Methods: A total of 120 extracted maxillary premolars were prepared with standardized MOD onlay cavities extending 2 mm below the cementoenamel junction. Teeth were embedded in acrylic resin and randomly allocated into 10 groups (n = 12), including two controls (positive and negative) and two experimental groups with or without DME.