Chelation of cerium (III) with fish skin collagen peptides: Improving the in vitro stability and bioavailability of inorganic cerium.

Purified fish skin collagen peptide (FSCP) was used to chelate Ce to prepare peptide‑cerium chelate (FSCP-Ce) to improve their in vitro stability and cellular uptake for oral delivery. The study revealed that the primary chelation sites between FSCP and Ce were located on the side chains of tryptophan, aspartic acid, glutamic acid, lysine and histidine (cerium-chelating capacity 75.32 mg/g).

Rescuing dendritic cell interstitial motility sustains antitumour immunity.

The dendritic cell (DC)-initiated and sustained cancer immunity cycle is indispensable for effective endogenous and therapeutically mobilized antitumour T cell responses. This necessitates the continuous migration of antigen-carrying DCs from the tumour microenvironment (TME) to the tumour draining lymph nodes (tdLNs). Here, through longitudinal analysis of human and mouse tumours, we observed a progressive decrease in migratory conventional DCs (mig-cDCs) in the tdLNs during tumour progression.

Sociological-Theory-Based Multitopic Self-Supervised Recommendation.

Social relationships offer crucial supplementary information for recommendations by leveraging users' social connections to gain insights into their preferences. However, prevalent social recommendation methods often grapple with the issues of sparsity and noise, which curtail their effectiveness. In addition, these methods overlook the intricacies of user interactions within social networks, which could provide invaluable information.

Organic pollutant degradation for micro-molecule product emission over SiO layers-coated g-CN photocatalysts.

In this study, a SiO layer-coated g-CN catalyst was prepared by a sol-gel method to overcome the poor adsorption ability and high recombination rate of charge carriers of pristine g-CN. SEM and TEM images indicated that SiO nanoparticles were coated on the surface of g-CN nanoparticles with a layered structure and the layers were tightly contacted with g-CN. XRD patterns, FTIR spectra, UV-vis spectra and XPS spectra revealed that the structure of g-CN was not destroyed and its photoelectric catalytic properties were not suppressed by the coating of SiO layers.

Effects of different high-temperature conduction modes on the ovalbumin-glucose model: AGEs production and regulation of glycated ovalbumin on gut microbiota.

Food high-temperature processing frequently induces the production of advanced glycation end products (AGEs) in the food industry. In this study, the effects of three high-temperature conduction modes on the AGEs production derived from ovalbumin (OVA)-glucose model and the regulation of glycated OVA on gut microbiota were investigated. The peak time of OVA shifted maximally from 13.

Use of sodium alginate coatings to improve bioavailability of liposomes containing DPP-IV inhibitory collagen peptides.

Sodium alginate (SA) was used to coat liposomes containing DPP-IV inhibitory collagen peptides to improve their stability and in vitro absorption for intra-oral delivery. The liposome structure as well as entrapment efficiency and DPP-IV inhibitory activity was characterized. The liposome stability was determined by measuring in vitro release rates and their gastrointestinal stability.

Focused Ultrasound Thalamotomy for the Treatment of Essential Tremor: A 2-Year Outcome Study of Chinese People.

Essential tremor (ET) is a common movement disorder among elderly individuals worldwide and is occasionally associated with a high risk for mild cognitive impairment and dementia. This retrospective study aimed to determine the clinical outcome of unilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy in Chinese patients with ET. In total, 31 male and 17 female patients with drug-refractory ET were enrolled in this research study from January 2017 to September 2019.

AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells.

The current coronavirus disease 2019 (COVID-19) pandemic presents a global public health challenge. The viral pathogen responsible, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), binds to the host receptor ACE2 through its spike (S) glycoprotein, which mediates membrane fusion and viral entry. Although the role of ACE2 as a receptor for SARS-CoV-2 is clear, studies have shown that ACE2 expression is extremely low in various human tissues, especially in the respiratory tract.