Acquired Brown Syndrome as a Postoperative Complication of Orbital Wall Fracture Repair with Metallic Mesh.

Surgical repair of orbital fractures comes with risks. One rare risk is interference with the actions of the superior oblique tendon-muscle complex causing an acquired Brown syndrome. We present the case of a 45-year-old man who developed acquired Brown syndrome after undergoing repair of a large orbital floor and medial orbital wall fracture using a titanium mesh implant.

Correlation of Point-of-Care Intestinal Ultrasound With Endoscopic Disease Severity in Crohn's Disease.

Background: Intestinal ultrasound is increasingly being used in the management of patients with inflammatory bowel disease (IBD). We aim to evaluate the accuracy of intestinal ultrasound in a point-of-care setting in India and compare it with ileo-colonoscopy, the current gold standard.

Methods: In this prospective observational study, consecutive patients with a diagnosis of Crohn's disease seen at initial presentation or follow-up were included.

A review on sustainable non-thermal approaches for pea protein: Pre-treatment, extraction, modification, and applications.

Pea protein is gaining global attention as a sustainable, plant-based alternative to animal proteins due to its lower environmental impact. However, conventional thermal processing methods can degrade its functional and nutritional properties. This review explores sustainable non-thermal approaches for pea protein processing, focusing on pre-treatment, extraction, and modification.

Does manipulative therapy with sodium chloride-fortified coconut (SCFC) oil affect cardio-respiratory variables in healthy individuals?

Background: Sodium chloride-fortified coconut (SCFC) oil massage is one of the manipulative procedures under the umbrella of complementary and alternative medicine (CAM) which is commonly employed as a wellness strategy. Due to the lack of scientific evidence, to implement it as a therapeutic tool, the goal of the current study was to evaluate how SCFC oil massage affected the cardio-respiratory characteristics of volunteers in good health.

Methods: The present study was a randomized control trial.

Effect of solid-state fermentation on kidney bean flour: Functional properties, mineral bioavailability, and product formulation.

This research investigated the effects of solid-state fermentation with (MTCC 548) on the mineral bioavailability, structural characteristics, and functional attributes of kidney bean flour across different fermentation durations (24-96 h). Notable improvements were observed during 96 h of fermentation, including significant increases in foaming capacity and stability (by 32.30 % and 34.

Cinnabarinic acid protects against metabolic dysfunction-associated steatohepatitis by activating aryl hydrocarbon receptor-dependent AMPK signaling.

Metabolic dysfunction-associated steatohepatitis (MASH) is an advanced form of metabolic dysfunction-associated steatotic liver disease (MASLD) characterized by the accumulation of fats in the liver, chronic inflammation, hepatocytic ballooning, and fibrosis. This study investigates the significance of hepatic aryl hydrocarbon receptor (AhR) signaling in cinnabarinic acid (CA)-mediated protection against MASH. Here, we report that livers of high-fat, high-fructose, high-cholesterol diet-fed hepatocyte-specific aryl hydrocarbon receptor knockout mice (AhR-hKO) exhibited aggravated steatosis, inflammation, and fibrosis compared with control AhR-floxed livers.

Additive Manufacturing and Functionalization of Hollow Polypropylene Sorbents for Water Remediation.

As the demand for clean water intensifies, developing effective methods for removing pollutants from contaminated sources becomes increasingly crucial. This work establishes a method for additive manufacturing of functional polymer sorbents with hollow porous features, designed to enhance interactions with organic micropollutants. Specifically, core-shell filaments are used as the starting materials, which contain polypropylene (PP) as the shell and poly(acrylonitrile-co-butadiene-co-styrene) as the core, to fabricate 3-dimensional (3D) structures on-demand via material extrusion.

Patterns of Extraocular Muscle Enlargement in Graves' Orbitopathy and Acromegaly.

Extraocular muscle (EOM) enlargement occurs in both acromegaly and Graves' disease, but the degree and pattern of enlargement have not been directly compared in these patient groups. This study investigated whether acromegaly and Graves' orbitopathy (GO) are associated with different patterns of EOM enlargement at the time of diagnosis. Retrospective cohort.

Standardisation of Blood Pressure Measurement Among Patients Attending an Urban Primary Health Centre: A Quality Improvement Initiative.

Accurate blood pressure (BP) measurement is essential for detecting, diagnosing, treating, and monitoring hypertensive individuals. This qualitative improvement initiative study is aimed at improving adherence to standardised BP measurement protocols in an urban primary health centre in Delhi, India. This study was conducted using a checklist based on World Health Organisation (WHO) guidelines.

Disparities in Vision-Related Functional Impairments Among Adults in the United States.

Purpose: To investigate the relationships between vision-related functional impairment (VFI) with sociodemographic and healthcare access factors in a representative sample of the United States population.

Methods: Data from the 2017 National Health Interview Survey (NHIS) were used. The NHIS involves responses from the U.

SOCIAL DETERMINANTS OF HEALTH IN AGE-RELATED MACULAR DEGENERATION: A Nationally Representative Survey Study.

Purpose: To investigate the relationship between social determinants of health and the prevalence of age-related macular degeneration (AMD).

Methods: This analysis included adult respondents (≥50 years old) from the 2017 National Health Interview Survey. The primary outcomes were self-reported diagnosis of AMD and self-reported vision loss because of AMD.

Association Between Sociodemographic Factors and Self-Reported Diabetic Retinopathy: A Cross-sectional, Population-Based Analysis.

Purpose: This study aimed to investigate the relationship between sociodemographic and healthcare access factors with self-reported diabetic retinopathy (DR) prevalence in a nationally representative sample of the United States.

Design: This is a population based, cross-sectional analysis.

Methods: Data from those who answered the question, "Have you ever been told by a doctor or other health professional that you had diabetic retinopathy?" from the 2017 National Health Interview Survey (NHIS) was analyzed through logistic regression to examine the association between DR prevalence and social determinants of health (SDH).

Use of Plasma Rich in Growth Factors for Ocular Surface Disorders: A Systematic Review.

Purpose: Ocular surface disorders (OSDs) can severely affect vision and quality of life. Autologous blood products, such as plasma rich in growth factors (PRGF), are recently available to treat OSDs refractory to traditional therapies. This review aims to summarize the efficacy and safety of PRGF in OSDs.

Recent advances in the analytical methods for quantitative determination of antioxidants in food matrices.

Antioxidants are crucial in reducing oxidative stress and enhancing health, necessitating precise quantification in food matrices. Advanced techniques such as biosensors and nanosensors offer high sensitivity and specificity, enabling real-time monitoring and accurate antioxidant quantification in complex food systems. These technologies herald a new era in food analysis, improving food quality and safety through sophisticated detection methods.

Evaluation of Pars Plana Vitrectomy With and Without Supplemental Scleral Buckle for the Repair of Rhegmatogenous Detachment Due to Inferior Retinal Breaks: A Systematic Review.

In this systematic review, the efficacy of scleral buckle (SB) with pars plana vitrectomy (PPV) was compared to PPV alone in eyes with rhegmatogenous retinal detachment (RRD) due to inferior retinal breaks (IRB). Measured outcomes included final best-corrected visual acuity (BCVA), anatomic success, and complication rates in randomized controlled trials and observational studies from 2000 to 2022. Among four studies (696 eyes), three studies demonstrated no significant difference between PPV and PPV/SB for final BCVA, whereas one study reported better BCVA with added SB.

Revamping Undergraduate Radiology Education in a Problem-Based Learning Driven Institution: Successes, Challenges, and Lessons Learned.

Radiology teaching for undergraduate medical students is often limited in amount and lacking a longitudinal approach spanning multiple years. At our institution, we had a goal to develop a formal and sustainable radiology curriculum. There were sequential changes made to the curriculum over several years and here, the successes, challenges, and lessons learned are outlined.

Exploration of Calocybe indica mushroom phenolic acid-kidney bean protein complex: Functional properties, amino acid profiles, in-vitro digestibility, and application in vegan product development.

The study evaluates the interaction between Calocybe indica mushroom polyphenols (phenolic acid) and kidney bean protein (KBPM), aiming to enhance vegan food quality. The mushrooms exhibited a carbohydrate content of 3.65%, an antioxidant activity of 55.

Physical and Psychosocial Challenges as Predictors of Vision Difficulty in Children: A Nationally Representative Survey Analysis.

Purpose: To elicit associations between vision difficulties and physical or psychosocial challenges in children in the United States.

Methods: Children aged 2-17 years old from the 2021 National Health Interview Survey with data pertaining to vision difficulty were included in our retrospective, population-based analysis. Our primary aim was investigating physical and psychosocial challenges as predictors of vision difficulty.

Extraction, Modification, Biofunctionality, and Food Applications of Chickpea Protein: An Up-to-Date Review.

Plant-based proteins have gained popularity in the food industry as a good protein source. Among these, chickpea protein has gained significant attention in recent times due to its high yields, high nutritional content, and health benefits. With an abundance of essential amino acids, particularly lysine, and a highly digestible indispensable amino acid score of 76 (DIAAS), chickpea protein is considered a substitute for animal proteins.

Effect of dual modifications with ultrasonication and succinylation on Cicer arietinum protein-iron complexes: Characterization, digestibility, in-vitro cellular mineral uptake and preparation of fortified smoothie.

The research aimed to evaluate the effect of ultrasonication and succinylation on the functional, iron binding, physiochemical, and cellular mineral uptake efficacy of chickpea protein concentrate. Succinylation resulted in significant improvements in the water-holding capacity (WHC) (25.47 %), oil-holding capacity (OHC) (31.

Hypotony and Anterior Uveitis following Dual Therapy with Nivolumab and Ipilimumab for Metastatic Melanoma: A Case Report.

Purpose: To describe a rare case of hypotony and anterior uveitis following dual therapy with nivolumab and ipilimumab for metastatic melanoma.

Methods: Case report.

Results: Here, we present the case of a 64-year-old man taking nivolumab and ipilimumab dual therapy for BRAF+ (v-raf murine sarcoma viral oncogene homolog B1) metastatic melanoma.

Eyedrop Instillation Techniques, Difficulties, and Currently Available Solutions: A Literature Review.

Purpose: To review current eyedrop instillation techniques, common difficulties faced by patients instilling eyedrops, available eyedrop assistive devices, and patient education regarding eyedrop instillation.

Methods: PubMed, Embase, and Google Scholar were searched from conception until June 2022 for articles on eyedrop instillation difficulties, techniques, tools, and patient education.

Results: Instillation involves pulling down the lower eyelids and placing drops on the corneal surface or conjunctival fornix, followed by closing of the eyelids for about 1 min.

Google Gemini and Bard artificial intelligence chatbot performance in ophthalmology knowledge assessment.

Purpose: With the popularization of ChatGPT (Open AI, San Francisco, California, United States) in recent months, understanding the potential of artificial intelligence (AI) chatbots in a medical context is important. Our study aims to evaluate Google Gemini and Bard's (Google, Mountain View, California, United States) knowledge in ophthalmology.

Methods: In this study, we evaluated Google Gemini and Bard's performance on EyeQuiz, a platform containing ophthalmology board certification examination practice questions, when used from the United States (US).