Publications by authors named "Kayal Vizhi Nagarajan"

Background: Intestinal ultrasound is increasingly being used in the management of patients with inflammatory bowel disease (IBD). We aim to evaluate the accuracy of intestinal ultrasound in a point-of-care setting in India and compare it with ileo-colonoscopy, the current gold standard.

Methods: In this prospective observational study, consecutive patients with a diagnosis of Crohn's disease seen at initial presentation or follow-up were included.

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Background & Aims: A primary aim in managing Crohn's disease (CD) is preventing bowel damage. The Lémann index (LI) quantifies structural bowel damage using magnetic resonance enterography (MRE) or computed tomography enterography (CTE) and, for colonic CD, colonoscopy. Intestinal ultrasonography (IUS) provides a noninvasive imaging alternative, although its role in LI assessment remains unexplored.

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Background: Japanese narrow band imaging expert team (JNET) classification has a diagnostic accuracy above 90% in differentiating neoplastic from non-neoplastic colonic polyps as well as estimating the depth of invasion in colorectal cancer. However, its validation outside Japan is limited to expert centers and requires magnifying endoscopes.

Aims And Methods: This study aimed at validating the JNET classification prospectively in a real-world setting in India using magnifying endoscopes with dual focus.

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Article Synopsis
  • Screening colonoscopy and polypectomy are essential for reducing colorectal cancer rates, especially as India's incidence of colonic polyps and cancer has been increasing despite overall low rates.
  • Proper training for healthcare providers in detecting and characterizing polyps is crucial, using techniques like high-definition endoscopy and image-enhanced tools to improve outcomes.
  • Advancements in GI endoscopy technology, including artificial intelligence and newer imaging methods, are promising and indicate a need for ongoing education in polyp management and prediction of advanced pathology.
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Intestinal ultrasound is an emerging technique for diagnosing and monitoring patients with inflammatory bowel disease (IBD). It is a simple, non-invasive, inexpensive, safe and reliable tool for monitoring patients with IBD. This technique has good diagnostic accuracy in the assessment of the extent and severity of IBD and its complications.

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Eosinophilic esophagitis (EoE) has evolved over the last three decades with a better understanding of the natural course of the disease. The prevalence of EoE is higher in Western countries with increasing reports of the incidence of EoE in the east. There is less data on EoE in India.

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