Publications by authors named "Miguel Cruz-Pimentel"
Purpose: To assess the variability in the incidence of rhegmatogenous retinal detachment (RRD) across seasons.
Methods: The study protocol was registered in PROSPERO (CRD42022378855) and the study was conducted in adherence to the Preferred Reporting Items for a Systematic Review and Meta-analysis (PRISMA) guidelines. A detailed search was conducted of Ovid MEDLINE, Ovid EMBASE, Cochrane Central Register of Controlled Trials and CINAHL.
Unilateral maculopathy associated with autosomal dominant bestrophinopathy.
Ophthalmic Genet
June 2025
Purpose: To describe the presentation of Best Vitelliform Macular Dystrophy (BVMD) as a unilateral maculopathy with bilateral retinal pigment epithelium (RPE) reduced function secondary to molecular changes or variants in gene.
Methods: Retrospective case series.
Results: Both patients exhibited unilateral anatomical changes during fundus examination caused by pathogenic variants in .
Purpose: To characterize proliferative vitreoretinopathy (PVR) with swept-source OCT (SS-OCT) in rhegmatogenous retinal detachment (RRD).
Design: Prospective cross sectional cohort study.
Subjects: Consecutive primary RRDs presenting to St.
Purpose: To describe in-office suprachoroidal viscopexy(SCVEXY) as a novel adjunct surgical technique with pneumatic retinopexy(PnR) for rhegmatogenous retinal detachment(RRD).
Methods: A 61-year-old pseudophakic male who was failing PnR for a macula-involving RRD underwent rescue SCVEXY at St. Michael's Hospital, Unity Health Toronto, Toronto, Canada.
Purpose: To investigate the association between baseline clinical characteristics of patients with diabetic macular edema (DME) and quantitative intravenous fluorescein angiography (IVFA) parameters.
Methods: Consecutive patients with DME presenting with a central macular thickness (CMT) ≥310 µ m were recruited from 2017 to 2023. Ultra-widefield IVFA images were analyzed with the RETICAD algorithm to extract quantitative measures of blood-retinal barrier (BRB) permeability, retinal perfusion, and blood flow.
Purpose: To comprehensively investigate the suprachoroidal space (SCS) in the context of rhegmatogenous retinal detachment (RRD) using swept-source optical coherence tomography.
Methods: We conducted a post hoc analysis of 90 consecutive patients with a primary RRD. Baseline swept-source optical coherence tomography scans were graded for the presence and thickness of SCS.
Purpose: To report the technique and long-term outcomes of patients with giant retinal tear-associated retinal detachment treated with pneumatic retinopexy (PnR).
Methods: Retrospective cohort study. All patients presenting with giant retinal tear-associated retinal detachment with tears in the superior ten-clock hours who underwent primary PnR were included in this study .
Purpose: To report a case of cytomegalovirus (CMV)-related hemorrhagic retinal vasculitis in a patient with multiple myeloma (MM) on daratumumab, a trial cereblon E3 ligase modulatory drug (CELMoD), dexamethasone, and acyclovir, and discuss clinical implications for CMV prophylaxis.
Methods: Case report, narrative review of CMV reactivation risk in MM patients on daratumumab and antiviral agent efficacy for CMV prophylaxis.
Results: A 63-year-old female presented with 3 days of progressive unilateral vision loss in the right eye to the level of counting fingers.
Roller Coasters and Retinal Detachment: Case Series and Review of Acceleration-Deceleration Retinal Injury.
Case Rep Ophthalmol
September 2024
Article Synopsis
- The text discusses a possible link between rapid acceleration from activities like roller coaster riding and retinal detachment, based on anecdotal and limited evidence.
- Two case studies are presented: a 24-year-old woman with a family history of retinal issues and a 25-year-old woman with high myopia, both experiencing retinal detachment after riding roller coasters.
- The conclusion suggests that while rapid forces may cause retinal detachment, structural predispositions, such as high myopia or family history, are likely necessary for such injuries to occur.
Article Synopsis
- This study evaluated the photoreceptor mosaic in patients with idiopathic full thickness macular holes before and after surgery using adaptive optics imaging.* -
- Conducted at the Kensington Eye Institute, the research excluded patients with certain conditions and involved detailed measurements of cone density and regularity in the retina.* -
- Results showed a significant decrease in cone density and changes in spacing and dispersion three months post-surgery, demonstrating the effectiveness of adaptive optics for assessing retinal health.*
Objective: To compare visual outcomes and complication risk based on the timing of pars plana vitrectomy (PPV) following cataract surgery with retained lens fragments.
Methods: MEDLINE (Ovid), EMBASE, and Cochrane Library were searched between 2000 to February 2022 for studies comparing visual outcomes and complications based on time to PPV. Discrete outcomes were analyzed using a random-effects meta-analysis model on Review Manager (RevMan 5.
Objective: To describe varying morphological features of patients with RRD based on the extent of regulation of the subretinal space by the retinal pigment epithelium (RPE) pump using swept-source optical coherence tomography (SS-OCT).
Design: Prospective clinical cohort study.
Methods: Setting: St.
Purpose: To elicit associations between vision difficulties and physical or psychosocial challenges in children in the United States.
Methods: Children aged 2-17 years old from the 2021 National Health Interview Survey with data pertaining to vision difficulty were included in our retrospective, population-based analysis. Our primary aim was investigating physical and psychosocial challenges as predictors of vision difficulty.
Diagnostic methods for primary vitreoretinal lymphoma: A systematic review.
Surv Ophthalmol
April 2024
Primary vitreoretinal lymphoma is a potentially aggressive intraocular malignancy with poor systemic prognosis and sometimes significant diagnostic delays as it may masquerade as chronic uveitis. Despite the variety of diagnostic techniques, it is unclear which modality is most accurate in the diagnosis of PVRL. A systematic literature search was conducted on Ovid MEDLINE, EMBASE and the Cochrane Controlled Register of Trials for studies published between January, 2000, and June, 2023.
View Article and Find Full Text PDFBackground: The comparative safety and efficacy of different doses of intravitreal triamcinolone acetonide (IVTA) for diabetic macular edema (DME) and macular edema (ME) secondary to retinal vein occlusion (RVO) is unclear.
Objectives: This meta-analysis aimed to compare the safety and efficacy of different doses of IVTA in this setting.
Methods: A systematic literature search for randomized clinical trials (RCTs) was conducted on Cochrane Library, Ovid MEDLINE, and EMBASE from January 2005 to May 2022.
Article Synopsis
- Recent clinical trials show that pegcetacoplan and avacincaptad pegol, which inhibit C3 and C5 respectively, can reduce GA growth by around 20% in a dose-dependent manner.
- However, while these treatments slow the progression of GA, they do not improve visual function and may lead to serious side effects like conversion to other eye diseases and retinal issues.
Topic: Comparing the efficacy and safety between combined and sequential pars plana vitrectomy and phacoemulsification for macular hole (MH) and epiretinal membrane (ERM).
Clinical Relevance: The standard of care for MH and ERM is vitrectomy, which increases the risk of developing cataract. Combined phacovitrectomy eliminates the need for a second surgery.
Purpose: This work reports a rare case of spontaneous suprachoroidal hemorrhage (SSCH) and summarizes the literature on its treatment options and outcomes.
Methods: A case report and comprehensive literature review are presented on the medical and surgical management of SSCH on PubMed from 1998 to 2021.
Results: The literature search revealed 58 studies, 33 of which included 52 eyes of 47 patients.
Comments on "Scleral Transillumination With Digital Heads-Up Display: A Novel Technique for Visualization During Vitrectomy Surgery".
Ophthalmic Surg Lasers Imaging Retina
December 2022