Tetrel, nonconventional hydrogen bonds, and noticeable role of dispersion in complexes of fluoroform and carbon dichalcogenides.

Weak noncovalent interactions in complexes between fluoroform and carbon dichalcogenides are explored using highly accurate quantum chemical calculations. Tetrel and hydrogen bonds stabilize these binary systems, with tetrel bonds dominating oxygen-containing complexes and hydrogen bonds prevailing in oxygen-free ones. Distinct characteristics are also found between the two groups in terms of electrostatic contributions.

A dataset on analysis of school-based management research from 1984 TO 2023.

The dataset aims to map scientific publications in the field of school-based management visually at the global level indexed by Scopus using Bibliometric analysis. It focuses on articles on School-Based Management at the international level. Research data were obtained from the Scopus database from 1984 to 2023 through the publish or perish software.

AC conductivity study of mechanochemically synthesized solid electrolytes of LiMPSCl (M = Ca, Mg, Ba, Zn, Al, Y).

Argyrodite-type solid electrolytes of LiPSCl doped with multivalent cations (Mg, Ba, Zn, Al, Y) were prepared a mechanochemical synthesis method. The lattice constant (), interplanar spacing (, , ), and micro-strain () showed that the doping elements were incorporated into the crystal structure of LiPSCl. The lattice constant and interplanar spacing of the doped samples were smaller than those of LiPSCl.

Solid-State Reaction Synthesis of MgAlO Spinel from MgO-AlO Composite Particles Prepared via Electrostatic Adsorption.

This paper presents the formation of magnesium aluminate spinel using composite particles prepared via electrostatic adsorption (ESA). Scanning electron microscopy (SEM) images confirmed the presence of AlO-MgO composite particles. A mixture of AlO and MgO raw materials was also prepared by using the conventional bead-milling method for comparison.

Protective Effects of Lanostane Triterpenoids from Chaga Mushroom in Human Keratinocytes, HaCaT Cells, against Inflammatory and Oxidative Stresses.

Inotodiol, a lanostane-type triterpenoid, and many phytochemicals from Chaga mushrooms have been investigated for various allergic diseases. However, the anti-aging and anti-inflammatory activities of inotodiol under different types of oxidative stress and the impact of inotodiol on collagen and hyaluronan synthesis have not been sufficiently studied. Lanostane triterpenoids-rich concentrate, which contained 10% inotodiol as major (inotodiol concentrate), was prepared from Chaga and compared with pure inotodiol in terms of anti-inflammatory activities on a human keratinocyte cell line, HaCaT cells, under various stimulations such as stimulation with ultraviolet (UV) B or tumor necrosis factor (TNF)-α.

Evaluation of Toxicity and Efficacy of Inotodiol as an Anti-Inflammatory Agent Using Animal Model.

Chaga mushroom () comprises polyphenolic compounds, triterpenoids, polysaccharides, and sterols. Among the triterpenoid components, inotodiol has been broadly examined because of its various biological activities. The purpose of this study is to examine inotodiol from a safety point of view and to present the potential possibilities of inotodiol for medical usage.

Enhancement of an In Vivo Anti-Inflammatory Activity of Oleanolic Acid through Glycosylation Occurring Naturally in .

(Lardizabalaceae) has been used as a traditional herbal medicine in Korea and China for its anti-inflammatory and analgesic properties. As part of a bioprospecting program aimed at the discovery of new bioactive compounds from Korean medicinal plants, a phytochemical study of leaves was carried out leading to isolation of two oleanane-type triterpene saponins, 3--[-d-glucopyranosyl (1→2)--l-arabinopyranosyl] oleanolic acid-28--[-d-glucopyranosyl (1→6)--d-glucopyranosyl] ester () and 3---l-arabinopyranosyl oleanolic acid-28--[-d-glucopyranosyl (1→6)--d-glucopyranosyl] ester (). Their structures were established unambiguously by spectroscopic methods such as one- and two-dimensional nuclear magnetic resonance and infrared spectroscopies, high-resolution electrospray ionization mass spectrometry and chemical reactions.

Anti-allergic effect of inotodiol, a lanostane triterpenoid from Chaga mushroom, via selective inhibition of mast cell function.

Inotodiol is a lanostane triterpenoid found only in Chaga mushroom. In the previous study investigating anti-allergic effects of fractionated Chaga mushroom extracts, we have found evidence that purified inotodiol holds an activity to suppress the mast cell function in vivo. To address the therapeutic relevance of the finding, in this study, we investigated whether inotodiol could also alleviate allergy symptoms observed in a chicken ovalbumin (cOVA)-induced mouse model of food allergy.

Chemical constituents of Vietnamese mangrove with antioxidant and alpha-glucosidase inhibitory activity.

Using various chromatographic techniques, a total of 15 compounds, including one novel megastigmane named tiliaceic acid A () and 14 known compounds, were isolated from the traditional medicinal Vietnamese mangrove . Their structures were confirmed based on spectroscopic experiments including, UV, 1 D- and 2 D-NMR, HR-ESI-MS, and ECD analysis. The antioxidant and α-glucosidase inhibitory activities of the isolated compounds from were evaluated for the first time.

Ginsenosides from Korean red ginseng modulate T cell function via the regulation of NF-AT-mediated IL-2 production.

Korean red ginseng is a traditional health food frequently used to prevent or treat various diseases worldwide. In this study, we evaluated the immunomodulatory activities of eleven compounds () isolated from Korean red ginseng, focusing on T cell function. First, the effects of the eleven compounds were studied on the regulation of IL-2, a potent T cell growth factor.

An update on obesity: Mental consequences and psychological interventions.

Besides physical consequences, obesity has negative psychological effects, thereby lowering human life quality. Major psychological consequences of this disorder includes depression, impaired body image, low self-esteem, eating disorders, stress and poor quality of life, which are correlated with age and gender. Physical interventions, mainly diet control and energy balance, have been widely applied to treat obesity; and some psychological interventions including behavioral therapy, cognitive behavioral therapy and hypnotherapy have showed some effects on obesity treatment.

An update on physical health and economic consequences of overweight and obesity.

Overweight and obesity (OW and OB) have been on the increase globally and posed health risks to the world's population of all ages, including pre-born babies, children, adolescents, adults and elderly people, via their comorbid conditions. Excellent examples of comorbidities associated with obesity include cancer, cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM). In this article, we aimed to review and update scientific evidence regarding the relationships between obesity and its common physical health consequences, including CVD, T2DM, hypertension, ischemic stroke, cancer, dyslipidemia and reproductive disorders.

Cytotoxic triterpene saponins from the mangrove Aegiceras corniculatum.

Using various chromatographic separations, sixteen compounds, including one new triterpene saponin named aegicoroside A (1), were isolated from the leaves of the Vietnamese mangrove Aegiceras corniculatum. Their structures were determined by spectroscopic methods such as 1D and 2D NMR and HR-ESI-MS. The cytotoxic activities of the isolated compounds against MCF7 (breast), HCT116 (colon), B16F10 (melanoma), and A549 (adenocarcinoma) cancer cell lines were also evaluated.

Anti-allergic effects of the ethanol extract of Syzygium formosum (Wall.) Masam leaves and its immunoregulatory mechanisms.

Ethnopharmacological Relevance: As documented in a Vietnamese traditional medical encyclopedia, Syzygium formosum (Wall.) Masam leaves have been routinely used among indigenous Vietnamese people for treatment of various allergy-like symptoms including dermatitis and rhinitis.

Aim Of The Study: Anti-allergic activity of S.

A new rearranged abietane diterpene from Clerodendrum inerme with antioxidant and cytotoxic activities.

Eight compounds were isolated from the leaves of Clerodendrum inerme, including one new rearranged abietane diterpene, crolerodendrum B (1). Their structures were determined by means of spectroscopic methods including one-dimensional and two-dimensional nuclear magnetic resonance (1-D and 2-DNMR), high-resolution electrospray ionisation mass spectrometry (HR-ESI-MS) and circular dichroism (CD). The DPPH radical scavenging and cytotoxic activities of isolated compounds against MCF7 (breast), HCT116 (colon) and B16F10 (melanoma) cancer cell lines were evaluated.

Improving the efficacy of type 1 diabetes therapy by transplantation of immunoisolated insulin-producing cells.

Type 1 diabetes occurs when pancreatic islet β-cells are damaged and are thus unable to secrete insulin. Pancreas- or islet-grafting therapy offers highly efficient treatment but is limited by inadequate donor islets or pancreases for transplantation. Stem-cell therapy holds tremendous potential and promises to enhance treatment efficiency by overcoming the limitations of traditional therapies.

Production of functional dendritic cells from menstrual blood--a new dendritic cell source for immune therapy.

Dendritic cells (DCs) are the most professional antigen-presenting cells of the mammalian immune system. They are able to phagocytize, process antigen materials, and then present them to the surface of other cells including T lymphocytes in the immune system. These capabilities make DC therapy become a novel and promising immune-therapeutic approach for cancer treatment as well as for cancer vaccination.