Implicating neuroinflammation in hippocampus, prefrontal cortex and amygdala with cognitive deficit: a narrative review.

Neuroinflammation is known to be a contributing factor for several neurological disorders as well as cognitive dysfunction. Different signalling pathways, and a variety of supporting cells of CNS are suggested to be involved in the progression of neurodegeneration. Among the factors contributing to neuroinflammation, peripheral inflammation takes a lead role according to recent research, since persistent peripheral inflammation is believed to disrupt the blood-brain barrier (BBB).

Bacterial lipopolysaccharide model of neuroinflammation-associated neurodegeneration in Wistar rats: A comparison between different durations of lipopolysaccharide induction.

Background And Aim: Bacterial lipopolysaccharide (LPS)-induced neuroinflammation can be the most dependable animal model for studying neurodegeneration mechanisms driven by systemic inflammation-induced neuroinflammation. Hence, this study aimed to standardize the LPS model of neuroinflammation by comparing the effect of relatively low-dose LPS administered for different durations on the induction of neurodegeneration in Wistar rats.

Materials And Methods: Six groups of six adult Wistar rats per group were used in the study.

Protective role of cod liver oil on hippocampal oxidative damage and neuronal count in Wistar rat model of comorbid depression.

Background: Proper nutrition and balanced diet have a profound influence on mental well-being. Nutritional psychiatry plays an important role in influencing a healthy mind and body. The animal model of chronic unpredictable stress has been considered the effective model to explore research on anxiety and depression.

Chronic unpredictable stress-induced inflammation and quantitative analysis of neurons of distinct brain regions in Wistar rat model of comorbid depression.

Background And Aim: Depression and anxiety are the most prominent neuropsychiatric disease and have been considered as the most burdensome diseases of society. The hippocampus and prefrontal cortex have a prominent role in stress-induced neurological disorders. Chronic unpredictable stress exposed rats are a perfect model in understanding comorbid depression and anxiety disorders.

Assessment of monoamine neurotransmitters in the cortex and cerebellum of gamma-irradiated mice: A neuromodulatory role of .

Introduction: Radiation is an important tool in the diagnostic and curative treatment of many cancers. Ionizing radiation induces many biochemical changes in the cells. The present study was designed to estimate the level of neurotransmitters in the distinct brain tissue of Swiss albino mice before exposing gamma radiation.

Protective Role of Co-administration of Vitamin D in Monosodium Glutamate Induced Obesity in Female Rats.

Purpose: Obesity in females is an emerging health problem. The consumption of MSG has been considered as a risk factor for obesity. The tastemakers in Chinese and fast foods, such as fish sauce and soy sauce, contain very high levels of glutamate.

Comparing Utility of Anthropometric Indices Based on Gender Differences in Predicting Dyslipidaemia in Healthy Adults.

Introduction: Anthropometry is a simple reliable method for quantifying body proportions by measuring body length, weight and circumferences.

Aim: Our intention in this study was to compare sensitivities and positive predictive values of waist circumference (WC), waist-hip ratio (WHR), waist-height ratio (WHtR) and body mass index (BMI) in identifying healthy subjects, males and females separately for identifying obesity associated dyslipidemia.

Materials And Methods: We analysed randomly selected 100 healthy subjects (males:58%, females:42%) between 25 and 60 years of age attending tertiary health care center in South India, after obtaining informed consent and Institutional Ethical Clearance.