Liquid biopsy technologies: innovations and future directions in breast cancer biomarker detection.

Globally, breast cancer is the most frequent type of cancer, and its early diagnosis and screening can significantly improve the probability of survival and quality of life of those affected. Liquid biopsy-based targets such as circulating tumor cells, circulating tumor DNA, and exosomes have been instrumental in the early discovery of cancer, and have been found to be effective in stage therapy, recurrence monitoring, and drug selection. Biosensors based on these target related biomarkers convert the tested substances into quantifiable signals such as electrical and optical signals through signal transduction, which has the advantages of high sensitivity, simple operation, and low invasiveness.

Aptamer-based DNAzyme walker electrochemical biosensing strategy for Acinetobacter baumannii detection.

In this study, an innovative electrochemical biosensor was developed for the rapid, specific, and sensitive detection of Acinetobacter baumannii without the need for sample pretreatment. The biosensor utilized an aptamer as a specific capture probe for A. baumannii and employed a self-powered DNAzyme walker cleavage cycle reaction to achieve signal amplification.

Multi-aptamer-mediated hairpin allosteric and aptamer-assisted CRISPR system for detection of S. pneumoniae and S. aureus.

A novel nucleic acid aptamer nanoprobes-mediated hairpin allosteric and aptamer-assisted CRISPR system for detection of Streptococcus pneumoniae and Staphylococcus aureus is presented. In this fluorescence assay system, utilizing the hairpin allosteric effect caused by the aptamer binding to the target bacteria, the detection of S. pneumoniae is first achieved through changes in fluorescence due to FRET.

Tailoring Morphologies, Photocatalytic Activity, and Energy Bands of BiFeO via Valence State Transformation of Doped V Ions.

Photocatalysts with suitable nanostructures and excellent photocatalytic activity driven by solar light are in great demand for rapidly eliminating the organic pollutants from wastewater. In order to improve the photocatalytic activities, three main factors should be considered, including band gap, band structure, and morphologies. Most of the previous studies only focused on manipulating one factor, such as the band gap by element doping.

Photoelectron transport tuning of self-assembled subbands.

Conventionally, electrical transport of quantum subbands occurs at very high electric fields, indicating that the medium is easy to break down. In the experiments and practical applications, the extreme condition is difficult to satisfy. For quantum information transmission, low power consumption and convenient implementation are what we expect.

[Study on the preparation and properties of novel silica microporous antireflective coating by sol-gel process].

Silica sol was prepared by acid catalyzed sol-gel process using tetraethylorthosilicate (TEOS) as precursor and dimethyldietoxysilane (DDS) as pore-forming agent. A novel kind of monolayer microporous silica anti-reflective (AR) coating was obtained on K9 glass substrate by dip-coating technique and then heat treated at 500 degrees C. The effects of different DDS/TEOS molar ratios on refractive index, transmittance and hardness were investigated.

[Synthsis and photoluminescence properties of low-T(g), photorefractive polymers of double function].

A group of low-T(g) photorefractive polymers of double function with carbazole and p-nitrodiazencarbazole called P-2, P-3 and P-4 were synthesized by means of different proportional diazonium salts being diazo-coupled with the poly [bis(6-carbazolhexyloxy)] phosphazene(P-1). P-2, P-3 and P-4 were characterized by 31P NMR, 1H NMR, IR, UV-Vis, GPC, TG and DSC. The result showed that P-2, P-3 and P-4 have good heat stability (T(d) approximately 300 degrees C) and a lower glass transition temperature (T(g) approximately 30-40 degrees C).