Glare suppressed 3D mapping system based on linear polarization filtering and binocular vision fusion.

To address the problem of large errors in 3D maps caused by mismatching due to white flares formed through specular reflections on smooth object surfaces during digital image acquisition, we propose applying the polarization principle to filter out the orthogonally polarized component of linearly polarized light in the reflected light, thereby reducing or eliminating the white flare area. The experimental results demonstrate that the system can effectively suppress the flare intensity on nonmetallic surfaces, which mitigates artifacts in 3D reconstruction.

Advances in the diagnosis and treatment of urethral metastasis after urothelial carcinoma surgery: A case series and literature review of 3 total ureterectomy cases.

Rationale: Urethral metastasis recurrence after surgery for urothelial carcinoma (UC) is a common clinical challenge, yet there is no established optimal treatment strategy to effectively control postoperative metastasis and recurrence. This case report evaluates the efficacy of total urethrectomy combined with adjuvant chemotherapy and PD-1 + antibody-drug conjugate (ADC) immunotherapy in managing UC urethral metastasis.

Patient Concerns: Three patients with a history of UC surgery presented with urethral metastasis recurrence, raising concerns about disease progression, treatment options, and long-term survival.

Integrated prognostic assessment of apoptosis and chemotherapy related gene in bladder cancer: a prognostic signature.

Background: Bladder cancer (BC), characterized by epithelial heterogeneity, remains a challenging malignancy with limited tissue biomarkers for anticipating neoadjuvant chemotherapy efficacy. Tumor progression, orchestrated by cancer cells, intricately involves the modulation of apoptosis-related pathways. Given their pivotal role in this cascade, apoptosis-related genes emerge as potential determinants of tumor development.

The genetic associations of lipidome on bladder cancer: a Mendelian randomization study.

Purpose: Multiple epidemiological studies have demonstrated a correlation between the lipidome and bladder cancer (BC). Nonetheless, the current literature lacks consensus on the causal link between the lipidome and BC. We utilise a two-sample Mendelian randomisation approach to meticulously evaluate the causal link between the two variables.

Spontaneous immobilization of single atom in NbCT MXene as excellent nanozyme for detecting and preventing gastric mucosal injury.

Early diagnosis and treatment of gastric mucosal injury is crucial to prevent further gastritis and even canceration. As an efficient biocatalyst, single-atom nanozyme (SAzyme) is proposed to be an ideal candidate for the construction of multifunctional platforms. Nevertheless, SAzyme still faces challenges in detecting and treating diseases due to the complexity of preparation methods, limitations of enzyme activity, and undesirable biocompatibility.

Exploration and validation of a novel reactive oxygen species-related signature for predicting the prognosis and chemotherapy response of patients with bladder cancer.

Background: Reactive Oxygen Species (ROS), a hallmark of cancer, is related to prognosis, tumor progression, and treatment response. Nevertheless, the correlation of ROS-based molecular signature with clinical outcome and immune cell infiltration has not been thoroughly studied in bladder cancer (BLCA). Accordingly, we aimed to thoroughly examine the role and prognostic value of ROS-related genes in BLCA.

Long-term survival of a kidney transplant patient with advanced renal cancer after combination therapy: a case report and literature review.

renal transplant carcinoma, especially in the context of bilateral renal carcinoma, is rare and often presents as small, low-grade papillary renal cell carcinoma (RCC). There is currently no consensus or effective treatment for advanced metastatic RCC after kidney transplantation. A 40-year-old man developed renal transplant carcinoma with venous thrombus and lung metastases 13 years after transplantation.

Progress in antibacterial applications of nanozymes.

Bacterial infections are a growing problem, and antibiotic drugs can be widely used to fight bacterial infections. However, the overuse of antibiotics and the evolution of bacteria have led to the emergence of drug-resistant bacteria, severely reducing the effectiveness of treatment. Therefore, it is very important to develop new effective antibacterial strategies to fight multi-drug resistant bacteria.

LINC00461 promotes bladder cancer cells EMT through miR-518b/HNRNPUL1 axis.

Bladder cancer (BC) is a prevalent type of tumor in the urinary system, and it has been discovered that long non-coding RNA (lncRNA) plays a significant role in its occurrence and development. However, thus far, no reports have been published on the involvement of LINC00461 in BC. Here, we found that LINC00461 levels were upregulated in BC tissues and cell lines.

m6A-Mediated Induction of 7-Dehydrocholesterol Reductase Stimulates Cholesterol Synthesis and cAMP Signaling to Promote Bladder Cancer Metastasis.

Dysregulation of cholesterol homeostasis occurs in multiple types of tumors and promotes cancer progression. Investigating the specific processes that induce abnormal cholesterol metabolism could identify therapeutic targets to improve cancer treatment. In this investigation, we observed upregulation of 7-dehydrocholesterol reductase (DHCR7), a vital enzyme involved in the synthesis of cholesterol, within bladder cancer tissues in comparison to normal tissues, which was correlated with increased bladder cancer metastasis.

A Notch signaling-related lncRNA signature for predicting prognosis and therapeutic response in clear cell renal cell carcinoma.

Increasing evidence has confirmed the vital role of Notch signaling in the tumorigenesis of clear cell renal cell carcinoma (ccRCC). The underlying function of long non-coding RNA (lncRNA) related to Notch signaling in ccRCC remains unclear. In present study, the prognostic value and therapeutic strategy of Notch signaling-related lncRNA are comprehensively explored in ccRCC.

Visible-Light-Promoted Intermolecular β-Acyl Difunctionalization of Alkenes via Oxidative Radical-Polar Crossover.

A visible-light-induced β-acyl difunctionalization of alkenes with acyl oxime esters and various nucleophiles was developed to achieve molecular complexity from readily available raw materials via oxidative radical-polar crossover. A variety of nucleophiles, including H-sulfoximines, indoles, indazole, and trimethoxybenzene, were all effectively applicable to the sustainable reaction system. The novel synthetic strategy features mild reaction conditions, a broad substrate scope (39 examples), easy scale-up, and excellent regioselectivity.

ANXA13 promotes cell proliferation and invasion and attenuates apoptosis in renal cell carcinoma.

Purpose: Emerging evidences have demonstrated that annexin A13 (ANXA13) is closely related to the occurrence and development of malignant tumors. However, the functions and underlying molecular mechanisms of ANXA13 in Clear cell renal cell carcinoma (ccRCC) have not been defined. Therefore, this study aimed to clarify the potential role of ANXA13 in regulating the proliferation, migration, invasion, cell cycle, and apoptosis of ccRCC cells.

Active visual mapping system for digital operation environment of bridge crane.

Bridge cranes must be able to sense their working environment to achieve autonomous operation. An active visual mapping system is presented in this research to adapt the measurement range based on the crane's operational state. The rotation angles of the two servos are computed based on the crane's speed so that the binocular camera is deflected and a greater field of view is gained in front, improving the crane's safety.

Perioperative outcomes of intracorporeal robot-assisted radical cystectomy versus open radical cystectomy: A systematic review and meta-analysis of comparative studies.

Purpose: To systematically review studies comparing the perioperative outcomes of intracorporeal robot-assisted radical cystectomy (iRARC) and open radical cystectomy (ORC).

Methods: Systematic searches of PubMed, Web of Science and the Cochrane Library were performed in June 2020. Studies with data comparing iRARC and ORC were included in our review, and a pooled meta-analysis was completed.

UBAC2 promotes bladder cancer proliferation through BCRC-3/miRNA-182-5p/p27 axis.

Emerging evidences have demonstrated that ubiquitin-associated domain-containing protein 2 (UBAC2) is closely related to the occurrence and development of malignant tumors. However, the functions and underlying molecular mechanisms of UBAC2 in bladder cancer (BC) development have not been defined. In this study, we found that both UBAC2 mRNA and protein levels were upregulated in BC tissues and cell lines, and knockdown of UBAC2 inhibited BC cells proliferation both in vitro and in vivo.