Publications by authors named "Junko Ishihara"

Background: One of the factors for not achieving a reduced salt diet may be the difficulties in screening individuals according to their quantitative salt consumption. Accordingly, we examined the performance of the simplified salt check sheet (13 items) as a quantitative tool for screening excessive salt intake by comparing with the salt intake amount measured by 24-hour urinary sodium (salt equivalent g/day) excretion.

Methods: One hundred fifty-four participants (57 males and 97 females) from Kanagawa, Tokyo, and Nara prefectures in Japan were included.

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Background: The Ministry of Health, Labour and Welfare in Japan has published a meal-based dietary guideline (Healthy Meal); however, its relationship with health outcomes remains unclear. This observational study examined the association between adherence to Healthy Meal and all-cause and cause-specific mortalities.

Methods: We analyzed data from the Japan Public Health Center-based Prospective Study (JPHC Study) with a mean follow-up of 19.

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Background And Objectives: Repeating food frequency questionnaires (FFQs) within the same population was reported to improve the validity of correlation coefficient (CC). However, the enhancement of validity in ranking agreement remains underreported. Herein, we assessed the validity of energy and nutrient intake es-timates using single and multiple FFQs and their ability to rank individuals.

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Background: Polyphenols may play a protective role in carcinogenesis through a wide range of properties, including antioxidant and anti-inflammatory. However, evidence for the association between total dietary polyphenol intake and cancer risk in Asian populations is limited.

Objective: This population-based prospective study aimed to investigate the association between polyphenol intake and risk of overall and site-specific cancer among Japanese.

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Background & Aims: Salt reduction remains an important issue in population-level studies of diet. One unresolved issue is whether adherence to a food guide which does not assess dietary salt can lead to a reduction in salt intake.

Methods: This study aimed to investigate the association between adherence to a food guide calculated by weighed food records (WFRs) or a Food Frequency Questionnaire (FFQ), and urinary sodium and potassium excretion and sodium-to-potassium ratio.

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Background: The Tohoku Medical Megabank Project has initiated the Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study) including genomic and omics investigations and conducted a self-administered food frequency questionnaire with the response option "constitutionally unable to eat or drink it" for individual food items (TMM-FFQ) for pregnant women. This study evaluated the validity of the TMM-FFQ among pregnant women.

Methods: Participants comprised 122 pregnant women aged ≥20 years residing in Miyagi Prefecture who completed weighed food records (WFRs) for 3 days as reference intake and the TMM-FFQ during mid-pregnancy.

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Recently, web-based dietary assessment tools for the targeted population have been developed and used to estimate the dietary intake level in several epidemiological studies. This study aimed to examine the validity of estimating energy and nutrient intake by the web-based 24 h dietary recall (Web24HR), which we developed for the Japanese population. Overall, 228 adults aged ≥20 years who agreed to participate were included.

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Article Synopsis
  • The Tohoku Medical Megabank Project (TMM) aims to enhance personalized healthcare using genomic data, focusing on evaluating a self-administered food frequency questionnaire (TMM-FFQ) among Japanese adults.
  • Participants (89 men and 124 women) recorded their food intake over 12 days and completed the FFQ in 2019 and 2021 to assess the questionnaire's validity and reproducibility.
  • Results showed that the TMM-FFQ demonstrated reasonable validity and reproducibility, with strong correlation coefficients for food group intakes and high percentages of accurate classification across food categories.
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Accurate measurement of sodium intake in the diet is challenging, and epidemiological studies can be hampered by the attenuation of associations due to measurement error in sodium intake. A prediction formula for habitual 24-h urine sodium excretion and sodium-to-potassium ratio might lead to more reliable conclusions. Five 24-h urinary samples and two Food Frequency Questionnaires (FFQs) were conducted among 244 Japanese participants aged 35-80 years.

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Background: Fruits and vegetables contain abundant amounts of antioxidant vitamins such as vitamin C, α-carotene, and β-carotene. Few prospective observational studies have investigated the effects of fruit and vegetable intake on the risk of dementia, and the results are inconsistent.

Objectives: Our aim was to examine associations between fruit and vegetable intake and the risk of disabling dementia.

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Because of within-individual variation, surveys to estimate an individual's usual food intake must be conducted over many days, in general. Here, using non-invasive biomarkers, we examined the number of measurements required to screen for the usual intake of fruit and vegetables, in addition to sodium, potassium, and the sodium-to-potassium (Na/K) ratio. Participants were 202 subjects aged 40-74 years from five areas of Japan who completed weighed food records (WFR) and five 24-hour urinary collections (24-h UCs) between 2012 and 2013.

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Article Synopsis
  • The Japanese food composition database was updated in 2020, expanding the variety and measurements of sugars, amino acids, and fatty acids, prompting a validation study using a food frequency questionnaire (long-FFQ).
  • A study involving 240 participants aged 40-74 compared the long-FFQ with a 12-day weighed food record, assessing validity through Spearman's correlation coefficients.
  • The long-FFQ showed reasonable validity in estimating nutrient intakes, particularly sugars, amino acids, and fatty acids, but highlighted the need for caution with certain nutrients, making it a useful tool for future studies.
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  • Recent studies suggest that polyphenols may help prevent chronic diseases, but their measurement's reliability over time is unclear.
  • This study assessed the consistency of 35 plasma polyphenols measured in participants a year apart, along with their relation to food intake from recorded diets.
  • Results showed stable levels of tea and coffee-derived polyphenols over the year, with significant correlations found between polyphenol levels and non-alcoholic beverage intake, especially green tea.
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Controlling avoidable causes of cancer may save cancer-related healthcare costs and indirect costs of premature deaths and productivity loss. This study aimed to estimate the economic burden of cancer attributable to major lifestyle and environmental risk factors in Japan in 2015. We evaluated the economic cost of cancer attributable to modifiable risk factors from a societal perspective.

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Background: Many epidemiological studies have investigated dietary intake of antioxidant vitamins in relation to prostate cancer risk in Western countries, but the results are inconsistent. However, few studies have reported this relationship in Asian countries.

Methods: We investigated the association between intake of vitamins, including lycopene, α-carotene, β-carotene, vitamin C, vitamin E, with prostate cancer risk in the Japan Public Health Center-based Prospective (JPHC) study.

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  • A study investigated the link between dairy product consumption and the risk of mortality from all causes, cancer, and cardiovascular diseases (CVD) in a Japanese cohort.
  • Data from over 93,000 participants showed that higher dairy intake was significantly associated with lower mortality rates for all causes and CVD in males, while no such association was found for females.
  • Overall, the findings suggest that for Japanese men, consuming more dairy can potentially reduce the risk of death from various health issues, particularly cardiovascular-related causes.
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The number of long-term survivors after a cancer diagnosis is increasing. Few investigations have compared survivors' diets to their original pre-diagnosis dietary pattern or with the patterns of cancer-free controls. We examined the dietary changes in survivors for five years (i.

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Background: Acrylamide (AA) is classified as "probably carcinogenic to humans (class 2A)" by the International Agency for Research on Cancer. AA causes cancer owing to its mutagenic and genotoxic metabolite, glycidamide (GA), and its effects on sex hormones. Both AA and GA can interact with hemoglobin to hemoglobin adducts (HbAA and HbGA, respectively), which are considered appropriate biomarkers of internal exposure of AA.

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  • The study aimed to validate a method for assessing trans fatty acid (TFA) intake in the Japanese population using a food frequency questionnaire (FFQ) developed in the 1990s.
  • A total of 565 participants aged 40-69 were included, and dietary intake was measured using a 28-day record along with two FFQs administered before and after the dietary record assessment.
  • Results indicated that the FFQ was reasonably valid and reproducible for estimating TFA intake, particularly in a population with low TFA consumption, with significant correlation coefficients found for both total TFA and its industrial and ruminant sources.
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It is worthwhile to discuss new environmental-related approaches to eating behavior that are effective throughout one's life course for better nutrition. Salt-reduction programs for children may benefit from strategies that actively engage families and teachers, according to a school-based cluster randomized controlled trial (School-EduSalt) in China to reduce salt intake in children and their families. Considering young people's lifestyle, a population-based approach for healthy low-risk people is necessary; for example, the use of an educational song consisting of interesting sounds and lyrics as BGM may be effective.

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Circadian misalignments have been linked to adverse cardiometabolic outcomes. However, the association between irregular daily routine and the risk of cardiovascular disease (CVD) remains unknown. We examined this association in a prospective study in Japan.

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Article Synopsis
  • * The analysis revealed that discretionary foods (like soup) contributed the highest percentage of Na intake (60.6%), while home-prepared dishes accounted for 84.0% of Na consumption.
  • * Non-discretionary sources, especially pickled products and certain fish, also significantly influenced urinary Na excretion, indicating that both discretionary and non-discretionary intakes are important in understanding sodium consumption.
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Using Food Frequency Questionnaires (FFQs) to compare dietary references for screening has been in high demand. However, FFQs have been widely used for ranking individuals in a population based on their dietary intake. We determined the validity of sodium (salt equivalent) intake, potassium intake, and sodium-to-potassium (Na/K) ratio obtained using the FFQ for identifying individuals who deviated from the dietary reference intakes (DRIs) measured using multiple 24-h urinary excretion measurements or 12-day weighed food records (WFR).

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