The European Nucleotide Archive (ENA, https://www.ebi.ac.
View Article and Find Full Text PDFLarge-scale reference genome sequencing projects for all of biodiversity are underway and common standards have been in place for some years to enable the understanding and sharing of sequence data. However, the metadata that describes the collection, processing and management of samples, and link to the associated sequencing and genome data, are not yet adequately developed and standardised for these projects. At the time of writing, the Darwin Tree of Life (DToL) Project is over two years into its ten-year ambition to sequence all described eukaryotic species in Britain and Ireland.
View Article and Find Full Text PDFBiodiversity loss is now recognised as one of the major challenges for humankind to address over the next few decades. Unless major actions are taken, the sixth mass extinction will lead to catastrophic effects on the Earth's biosphere and human health and well-being. ELIXIR can help address the technical challenges of biodiversity science, through leveraging its suite of services and expertise to enable data management and analysis activities that enhance our understanding of life on Earth and facilitate biodiversity preservation and restoration.
View Article and Find Full Text PDFThe European Nucleotide Archive (ENA; https://www.ebi.ac.
View Article and Find Full Text PDFAn increasingly common output arising from the analysis of shotgun metagenomic datasets is the generation of metagenome-assembled genomes (MAGs), with tens of thousands of MAGs now described in the literature. However, the discovery and comparison of these MAG collections is hampered by the lack of uniformity in their generation, annotation and storage. To address this, we have developed MGnify Genomes, a growing collection of biome-specific non-redundant microbial genome catalogues generated using MAGs and publicly available isolate genomes.
View Article and Find Full Text PDFNucleic Acids Res
January 2023
The MGnify platform (https://www.ebi.ac.
View Article and Find Full Text PDFThe European Nucleotide Archive (ENA; https://www.ebi.ac.
View Article and Find Full Text PDFThe European Nucleotide Archive (ENA, https://www.ebi.ac.
View Article and Find Full Text PDFMicrobiome samples are inherently defined by the environment in which they are found. Therefore, data that provide context and enable interpretation of measurements produced from biological samples, often referred to as metadata, are critical. Important contributions have been made in the development of community-driven metadata standards; however, these standards have not been uniformly embraced by the microbiome research community.
View Article and Find Full Text PDFThe European Nucleotide Archive (ENA; https://www.ebi.ac.
View Article and Find Full Text PDFNucleic Acids Res
January 2020
The European Nucleotide Archive (ENA, https://www.ebi.ac.
View Article and Find Full Text PDFMGnify (http://www.ebi.ac.
View Article and Find Full Text PDFBioinformatics
August 2019
Summary: Bionano optical mapping is a technology that can assist in the final stages of genome assembly by lengthening and ordering scaffolds in a draft assembly by aligning the assembly to a genomic map. However, currently, tools for visualization are limited to use on a Windows operating system or are developed initially for visualizing large-scale structural variation. MapOptics is a lightweight cross-platform tool that enables the user to visualize and interact with the alignment of Bionano optical mapping data and can be used for in depth exploration of hybrid scaffolding alignments.
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