Polarity-Switching Photoelectrochemical Biosensor Enabled by Metal/Semiconductor Nanostructures for Ultrasensitive MicroRNA Detection.

Developing efficient and accurate photoelectrochemical (PEC) sensing strategies to eliminate potential false positive or negative signals is crucial for practical applications. In this work, we report a PEC sensing strategy based on CuO nanoparticle-induced photocurrent polarity switching in a heterostructure of InP/ZnS quantum dots (QDs) combined with PdPt nanospheres (InP/ZnS@PdPt). The PdPt nanospheres not only provide versatile support for loading InP/ZnS QDs but also enable a 10-fold enhancement in the PEC activity of the InP/ZnS@PdPt compared to InP/ZnS QDs, attributed to the combined influence of localized surface plasmon resonance and the Schottky junction.

Pakchoi ( L.) Modulates the Antioxidant System and Energy Metabolism in Response to 6PPD and 6PPD-Q.

The widespread presence of the emerging contaminants -(1,3-dimethylbutyl)-'-phenyl--phenylenediamine (6PPD) and its derivative 6PPD-quinone (6PPD-Q), along with their associated environmental risks, has garnered significant public concern. To assess the food safety risk of 6PPD and its oxidized product 6PPD-Q in the environment, we explored the effects of different concentrations (0.1, 1, 10, and 100 μg/L) of 6PPD and 6PPD-Q on pakchoi ( L.

6PPD and 6PPD-Q Inhibit Macrophyte Photosynthesis by Targeting Photosynthetic Antenna: Multiomics and Computational Modeling Insights.

Emerging evidence indicates that -(1,3-dimethylbutyl)-'-phenyl--phenylenediamine (6PPD) and its derivative 6PPD-quinone (6PPD-Q) exert photosynthetic toxicity on aquatic macrophytes. However, their precise inhibitory mechanisms and toxic targets within the photosynthetic pathways remain poorly understood. Through a combination of physio-biochemical indicators, multiomics analysis, and molecular docking simulation, this study systematically explored the photosynthetic toxic effects of 6PPD and 6PPD-Q on L.

Metabolomic alterations reveal toxic mechanisms of single and combined 6PPD and arsenic exposure on mung bean (Vigna radiata).

N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a typical antioxidant present in rubber products, is detected at significant concentrations across multiple environmental compartments. However, there is no existing knowledge on the single and combined effect of 6PPD and arsenic (As) on terrestrial plants. This study examined the effects of 6PPD (1, 5, 10 and 20 µg L⁻¹) and its combination with arsenic (500 µg L⁻¹ As + 6PPD) on physio-biochemical characteristics and metabolomics of mung beans (Vigna radiata) after 21 days of exposure.

Tire Rubber Antioxidant 6PPD and 6PPD-quinone Disrupt the Energy Supply and Lipid Metabolism of Earthworms.

With the increase in traffic due to urbanization, tire wear particles (TWPs) derived compounds persistently accumulate in the soil environment. This study addresses critical knowledge gaps regarding the ecotoxicological effects of TWP-derived contaminants, -(1,3-dimethylbutyl)-'-phenyl--phenylenediamine (6PPD) and its precursor, 6PPD-quinone (6PPD-Q), on soil-dwelling organisms. The findings demonstrated that 6PPD-Q accumulated at a higher concentration (6.

Precision reactive species scavenging enabled by engineered manganese-doped bimetallic MOF for tailored stem cell fate regulation.

The development of highly efficient antioxidant nanomaterials is crucial for protecting stem cells from oxidative stress, a major challenge in advancing stem cell therapy and tissue regeneration. While most existing materials focus on scavenging reactive oxygen species (ROS), the often-overlooked contribution of reactive nitrogen species (RNS) further amplifies oxidative damage, limiting therapeutic efficacy. Here, we report a manganese-doped bimetallic metal-organic framework (MOF), Dex@(Mn, Zn)EZIF-8, with a hollow architecture designed for precise ROS/RNS scavenging and osteogenic regulation.

Marine-inspired near-infrared-activated multifunctional hydrogel with immunomodulatory properties for multidrug-resistant bacterial infected wound healing.

Multidrug-resistant (MDR) bacterial infections in skin wounds have become a critical medical challenge due to the diminishing effectiveness of available antibiotics. Persistent bacterial infections, excessive reactive oxygen and nitrogen species (ROS/RNS), and prolonged inflammatory responses significantly impede the wound healing process. To address these challenges, we propose a marine-inspired multifunctional 3AGM hydrogel designed to provide comprehensive antibacterial action, mitigate oxidative stress, and promote wound healing throughout the treatment process.

Foliar exposure to microplastics disrupts lettuce metabolism and negatively interferes with symbiotic microbial communities.

Plant leaves are considered an important sink for atmospheric microplastics (MPs) because they serve as a vital interface between the atmosphere and terrestrial ecosystems. However, there is still a dearth of information regarding how plant-symbiotic microbe-soil systems are affected by foliar exposure to MPs. In this study, MPs (polystyrene (PS), polyethylene (PE), and polypropylene (PP)) were sprayed over soil-cultivated lettuce (Lactuca sativa L.

Effects of compound immobilized bacteria on remediation and bacterial community of PAHs-contaminated soil.

Immobilized microorganism technology is expected to enhance microbial activity and stability and is considered an effective technique for removing soil polycyclic aromatic hydrocarbons (PAHs). However, there are limited high-efficiency and stable bacterial preparations available. In this study, alkali-modified biochar (Na@CBC700) was used as the adsorption carrier, sodium alginate (SA) and polyvinyl alcohol (PVA) as embedding agents, and CaCl as the cross-linking agent to prepare immobilized Acinetobacter (CoIMB) through a composite immobilization method.

Environmental occurrence, fate, human exposure, and human health risks of p-phenylenediamines and their quinones.

P-phenylenediamine antioxidants (PPDs) are widely used in the rubber industry and their release and transformation in the environment has become one of the current environmental research hotspots. PPDs are readily oxidized in the environment to form quinone transformation products (PPD-Qs), some of which (e.g.

Impact of Pristine and Aged Tire Wear Particles on and Rhizospheric Microbial Communities: Insights from a Long-Term Exposure Study.

Tire wear particles (TWPs), generated from tire abrasion, contribute significantly to environmental contamination. The toxicity of TWPs to organisms has raised significant concerns, yet their effects on terrestrial plants remain unclear. Here, we investigated the long-term impact of pristine and naturally aged TWPs on water spinach () and its rhizospheric soil.

Phytotoxicity of 6PPD and its uptake by Myriophyllum verticillatum: Oxidative stress and metabolic processes.

N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a widely utilized antioxidant in automobile tires and rubber goods, is frequently detected in aquatic ecosystems and poses a potential threat to aquatic organisms. However, research on the impact of 6PPD on aquatic plants is still scarce. Here, we investigated the bioaccumulation of 6PPD in Myriophyllum verticillatum (M.

Impact of microplastics on plant physiology: A meta-analysis of dose, particle size, and crop type interactions in agricultural ecosystems.

The increasing prevalence of plastic pollution has led to widespread environmental concerns, particularly with microplastics (MPs) that persist in various ecosystems. As MPs accumulate in terrestrial environments, their potential impact on plant health and agricultural productivity has become a growing area of focus. This study presents a comprehensive meta-analysis evaluating the effects of MPs on plant physiological and biochemical parameters, synthesizing data from 37 studies comprising 2886 observations.

Earthworms Enhance Crop Resistance to Insects Under Microplastic Stress by Mobilizing Physical and Chemical Defenses.

To assess the ecological risk of microplastics (MPs) in agricultural systems, it is critical to simultaneously focus on MP-mediated single-organism response and different trophic-level organism interaction. Herein, we placed earthworms in soils contaminated with different concentrations (0.02% and 0.

Environmental concentrations of 6PPD and 6PPD-Q cause oxidative damage and alter metabolism in Eichhornia crassipes.

N-(1,3-dimethylbutyl)-N '-phenyl-p-phenylenediamine (6PPD) and N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q) are ubiquitous in the environment and can cause toxicity to aquatic animals. However, research on the toxicological effects of 6PPD and 6PPD-Q on aquatic plants remains limited. The present study investigated the physiological, biochemical, and metabolic responses of the floating aquatic plant Eichhornia crassipes (E.

Comparative toxic effect of tire wear particle-derived compounds 6PPD and 6PPD-quinone to Chlorella vulgaris.

N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a widely used antioxidant in rubber products, and its corresponding ozone photolysis product N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine-quinone (6PPD-Q), have raised public concerns due to their environmental toxicity. However, there is an existing knowledge gap on the toxicity of 6PPD and 6PPD-Q to aquatic plants. A model aquatic plant, Chlorella vulgaris (C.

Earthworms improve the rhizosphere micro-environment to mitigate the toxicity of microplastics to tomato (Solanum lycopersicum).

Microplastics (MPs) are widespread in agricultural soil, potentially threatening soil environmental quality and plant growth. However, toxicological research on MPs has mainly been limited to individual components (such as plants, microbes, and animals), without considering their interactions. Here, we examined earthworm-mediated effects on tomato growth and the rhizosphere micro-environment under MPs contamination.

Atomic-Level Tailoring of the Electronic Metal-Support Interaction Between Pt-CoO Interfaces for High Hydrogen Evolution Performance.

Atomic-level modulation of the metal-oxide interface is considered an effective approach to optimize the electronic structure and catalytic activity of metal catalysts but remains highly challenging. Here, we employ the atomic layer deposition (ALD) technique together with a heteroatom doping strategy to effectively tailor the electronic metal-support interaction (EMSI) at the metal-oxide interface on the atomic level, thereby achieving high hydrogen evolution performance and Pt utilization. Theoretical calculations reveal that the doping of N atoms in CoO significantly adjusts the EMSI between Pt-CoO interfaces and, consequently, alters the d-band center of Pt and optimizes the adsorption/desorption of reaction intermediates.

Effects of polystyrene, polyethylene, and polypropylene microplastics on the soil-rhizosphere-plant system: Phytotoxicity, enzyme activity, and microbial community.

The widespread presence of soil microplastics (MPs) has become a global environmental problem. MPs of different properties (i.e.

Genes associated with inflammation for prognosis prediction for clear cell renal cell carcinoma: a multi-database analysis.

Background: Clear cell renal cell carcinoma (ccRCC) is the largest subtype of kidney tumour, with inflammatory responses characterising all stages of the tumour. Establishing the relationship between the genes related to inflammatory responses and ccRCC may help the diagnosis and treatment of patients with ccRCC.

Methods: First, we obtained the data for this study from a public database.

Integrating metabolomics and high-throughput sequencing to investigate the effects of tire wear particles on mung bean plants and soil microbial communities.

Tire wear particles (TWPs) generated by vehicle tires are ubiquitous in soil ecosystems, while their impact on soil biota remains poorly understood. In this study, we investigated the effects of TWPs (0.1%, 0.

Assessing stress responses in potherb mustard (Brassica juncea var. multiceps) exposed to a synergy of microplastics and cadmium: Insights from physiology, oxidative damage, and metabolomics.

Both microplastics (MPs) and cadmium (Cd) are common contaminants in farmland systems, is crucial for assessing their risks for human health and environment, and little research has focused on stress responses mechanisms of crops exposed to the combined pollution. The present study investigated the impact of polyethylene (PE) and polypropylene (PP) microplastics (MPs), in combination with Cd, on the physiological and metabolomic changes as well as rhizosphere soil of potherb mustard. Elevated levels of PEMPs and PPMPs were found to impede nutrient uptake in plants while promoting premature flowering, and the concomitant effect is lower crop yields.

Environmental fate, aging, toxicity and potential remediation strategies of microplastics in soil environment: Current progress and future perspectives.

Microplastics (MPs) are small plastic debris (<5 mm) that result from the fragmentation of plastic due to physical and physiochemical processes. MPs are emerging pollutants that pose a significant threat to the environment and human health, primarily due to their pervasive presence and potential bioaccumulation within the food web. Despite their importance, there is a lack of comprehensive studies on the fate, toxicity, and aging behavior of MPs.