A novel multi-parameter MRI-based model for identification of high-risk metabolic dysfunction-associated steatohepatitis.

Objectives: To develop and evaluate a novel multi-parameter MRI-based model (EFT1) for identifying high-risk metabolic dysfunction-associated steatohepatitis (MASH) to improve diagnostic accuracy and efficiency.

Materials And Methods: A prospective study included 118 patients (55 male; 48 ± 13 years) with hepatic steatosis and metabolic risk factors. Among these, 80 patients were classified as having high-risk MASH.

Preliminary Monitoring and Observation of Fuel Cell Temperature Characteristics by Using NiCr-NiSi Thin-Film Thermocouple.

This study presents the calibration methodology of NiCr-NiSi thin-film thermocouples and evaluates their application in real-time temperature monitoring and characterization of fuel cell thermal behavior. Experimental results reveal that the Seebeck coefficients of the NiCr-NiSi thin films remain stable after multiple calibration cycles, indicating good reliability and repeatability. Furthermore, the thermocouples demonstrate an ultrafast response time of less than 15 microseconds and reach thermal equilibrium within 200 microseconds under transient thermal inputs.

Jasmonic Acid Activates Transcription Factor SlMYB13 to Enhance Cold Resistance in Tomato.

Plant cold stress caused by cold waves often occurs during winter and spring, and seriously affects the growth and yield of tomatoes in horticultural facilities. The cultivation of cold-resistant tomato varieties during winter is therefore of great significance. Methyl jasmonate (MeJA) treatment is known to improve tomato cold tolerance.

NAC Transcription Factor LpNAC22 Positively Regulates Drought Tolerance in Perennial Ryegrass.

Drought serves as a major environmental stress that restricts both the yield and quality of perennial ryegrass. Therefore, it is important to identify the essential genes that determine drought tolerance in perennial ryegrasses. In this paper, we isolated a drought-induced NAC transcription factor LpNAC22.

Advances in multimodal electrohydrodynamic printing for high-resolution sensor fabrication: mechanisms, materials, and applications.

With the rapid development of micro-electromechanical systems (MEMS) and the manufacturing industry, the trends toward sensor intelligence, miniaturization, and flexibility have attracted significant attention while posing higher demands for high-resolution patterning and large-scale production. However, traditional manufacturing technologies exhibit significant limitations in achieving high resolution and multifunctional integration. Electrohydrodynamic (EHD) printing technology, which harnesses the synergistic effects of electric fields and fluid dynamics, enables precise control over the formation and deposition of micro-nanometer jets.

Deep generative model for protein subcellular localization prediction.

Protein sequence not only determines its structure but also provides important clues of its subcellular localization. Although a series of artificial intelligence models have been reported to predict protein subcellular localization, most of them provide only textual outputs. Here, we present deepGPS, a deep generative model for protein subcellular localization prediction.

Automated program using convolutional neural networks for objective and reproducible selection of corneal confocal microscopy images.

Objective: Diabetic peripheral neuropathy (DPN) is a common complication of diabetes, posing a significant risk for foot ulcers and amputation. Corneal confocal microscopy (CCM) is a rapid, noninvasive method to assess DPN by analysing corneal nerve fibre morphology. However, selecting high-quality representative images remains a critical challenge.

Phase behavior, physicochemical and rheological characteristics of low oil phase Pickering emulsion gels stabilized by whey protein isolate-γ-oryzanol aggregated particles: Roles of pH and temperature.

Low oil phase Pickering emulsion gels (LOPPEGs) with 15 % oil content was developed by heat-induced whey protein isolate-γ-oryzanol (WPI-γS) aggregated particles at different pH. Results of appearances and texture properties demonstrated that WPI-γS aggregated particles induced by the combination of pH and heating exhibited gel state. Surface hydrophobicity of WPI-γS/pH 7.

Consequence of high-pressure homogenization on the whipping characteristics of soybean oil body cream.

The study explored the effect of different high-pressure homogenization (HPH) pressure (30-70 MPa) on the whipping characteristics of soybean oil body (SOB) cream. With the increase of HPH treatment, fat globules were further broken, and their adsorption on the interface was promoted, which further enhanced the stability of cream, leading to smaller particle size and higher apparent viscosity. Moreover, whipping performance of cream is the best at 30 MPa.

Diets supplemented with different solvents extracts of Lepista nuda alters longevity and fecundity, and the expression of related genes in Drosophila melanogaster (Diptera: Drosophilidae).

Exploring the effects of different solvent extracts from Lepista nuda [(Bull. ex Fr.) Cooke] on the lifespan and reproductive capacity of Drosophila melanogaster (Diptera: Drosophilidae), the extracts of the fruiting body and mycelium of L.

Progress and recommendations of developing occupational exposure limits for noise-A systematic review.

Objective: Noise exposure limit is one of the critical measures to prevent noise-induced hearing loss (NIHL). This review aimed to review the progress and recommendations for developing occupational exposure limits (OELs) for workplace noise.

Methods: A systematic review was used.

Geometric Morphometrics and Genetic Diversity Analysis of Chalcidoidea ( and ) at Various Elevations.

Eulophidae and Pteromalidae are parasitic wasps with a global distribution and import for the biological control of pests. They can be distributed in different altitude regions, but their morphological and genetic adaptations to different altitudes are unclear. Here, we collected specimens that belong to Eulophidae and Pteromalidae from various altitudinal gradients, based on integrated taxonomic approaches to determine the species composition, and we analyzed their body shape and size from different altitudes using geometric morphometrics.

miR-122-3p targets UBE2I to regulate the immunosuppression of liver cancer and the intervention of Liujunzi formula.

Ethnopharmacological Relevance: Liujunzi formula has been used to treat liver cancer in China for many years, but its underlying mechanism remains unclear. We previously found that decreased expression of miR-122-3p was associated with liver cancer. In this study, we aimed to explore the target of miR-122-3p and the effect of the Liujunzi formula on miR-122-3p and its downstream events in liver cancer.

Mechanical energy triggered piezo-catalyzation of BiWO nanoplates on ferrate (Fe(VI)) oxidation in alkaline media: Performance and mechanism.

Piezo-electricity, as a unique physical phenomenon, demonstrates high effectiveness in capturing the environmental mechanical energy into polarization charges, offering the possibility to activate the advanced oxidation processes via the electron pathway. However, information regarding the intensification of Fe(VI) through piezo-catalysis is limited. Therefore, our study is the first to apply BiWO nanoplates for piezo-catalyzation of Fe(VI) to enhance bisphenol A (BPA) degradation.

A two-stage Fe(VI) oxidation process enhances the removal of bisphenol A for potential application.

Ferrate (Fe(VI)) has been extensively studied as a green oxidant to treat wastewater. But Fe(VI) oxidation still faces several challenges for application, such as the sensitivity of Fe(VI) to pH and the restrictions on the Fe(VI) utilization efficiency for pollutant elimination at low concentration levels. This study proposed a two-stage Fe(VI) oxidation process to enhance the bisphenol A (BPA) removal for potential applicability, consisting of the adsorption by CNTs of stage I and the degradation by Fe(VI) of stage II.

Flexible and excellent electromagnetic interference shielding film with porous alternating PVA-derived carbon and graphene layers.

Recently, the design of graphene-based films with elaborately controlled microstructures and optimized electromagnetic interference shielding (EMI) properties can effectively improve EM energy attenuation and conversion. Herein, inspired by the structure of multi-layer steamed bread, an alternating multilayered structure with polyvinyl alcohol (PVA)-derived carbon layers and graphene/electrospun carbon nanofibers layers was designed through alternating vacuum-assisted filtration method. The composite film exhibited favorable impedance matching, abundant loss mechanism, and excellent EMI shielding ability, resulting in absorption dominated shielding characteristic.

Observation of induction period and oxygenated intermediates in methane oxidation over Pt catalyst.

Selective oxidation of methane is one of the most attractive routes for methane to chemicals. However, mechanistic understanding and avoiding over-oxidation have great challenges because of its very rapid reaction rate. Herein, a capillary micro-reaction system was introduced to monitor the initial stage of methane oxidation over platinum.

Evaluating the role of glycyrrhizic acid on the dynamic stabilization mechanism of the emulsion prepared by α-Lactalbumin: Experimental and silico approaches.

The role of glycyrrhizic acid (GA) on the dynamic stabilization mechanism of the α-Lactalbumin (α-La) emulsion was evaluated in this study. Smaller particle size and higher zeta potential value were observed in the α-La/GA emulsion as compared to the α-La emulsion. Ultra-high-resolution microscopy revealed that the interfacial film formed around oil droplets by α-La/GA complex was thicker compared to that of either α-La or GA.

Extrusion of casein and whey protein isolate enhances anti-hardening and performance in high-protein nutrition bars.

Model high-protein nutrition bars (HPNBs) were formulated by incorporating whey protein isolate (WPI) and casein (CN) at various extrusion temperatures (50, 75, 100, 125, and 150 °C) with a protein content of 45 g per 100 g. The free sulfhydryl groups, amino groups, hardness, and microstructures of HPNBs were analyzed periodically at 37 °C over a storage period of 45 days. Specifically, sulfhydryl group, amino group and surface hydrophobicity of extruded whey protein isolate (WPE) and extruded casein (CE) were significantly reduced (P < 0.

Comparison of toxic effects of 5 macrofungi against Drosophila melanogaster.

Traditional chemical pesticides pose potential threats to human health, the environment, and food safety, and there is an urgent need to develop botanical pesticides that are easily degradable, renewable, and environmentally compatible. This research serves to detect the lethal impacts of Amanita pantherina(DC.:Fr) Schrmm.

Benzene metabolite hydroquinone enhances self-renewal and proliferation of preleukemic cells through the Ppar-γ pathway.

Benzene is a known hematotoxic and leukemogenic chemical. Exposure to benzene cause inhibition of hematopoietic cells. However, the mechanism of how the hematopoietic cells inhibited by benzene undergo malignant proliferation is unknown.

Impact of invertebrates on water quality safety and their sheltering effect on bacteria in water supply systems.

Invertebrates in drinking water not only affect human health, but also provide migration and shelter for pathogenic microorganisms. Their residues and metabolites also produce DBPs (disinfection by-products), which have adverse effects on the health of residents. In this study, the contributions of the rotifers and nematodes to the BDOC (biodegradable dissolved organic carbon), BRP (bacterial regrowth potential) and DBPs in drinking water were explored, and the sheltering effects of chlorine-resistant invertebrates on indigenous bacteria and pathogenic bacteria were studied, and the health and safety risk of invertebrates in drinking water was also assessed.

Fe(VI) activation system mediated by a solar-driven TiO nanotubes electrode for CLQ degradation: Performances, mechanisms and pathways.

Ferrate (Fe(VI), FeO) has been widely used in the degradation of micropollutants with the advantages of high redox potential, no secondary pollution and inhibition of disinfection byproducts. However, the low transformation of Fe(V) and/or Fe(IV) by Fe(VI) and incomplete mineralization of pollutants limit their application. In this work, we designed a photo electric cell with TiO nanotubes (TNTs) and Pt serving as the anode and cathode to enhance the utilization of Fe(VI) (Fe(VI)-TNTs system).