Hierarchical MoS/Poly(ionic liquid) Metamaterials for Electrically Tunable Terahertz Stealth.

Active absorption modulation is critical for advanced stealth technologies, especially given the emerging detection threat from terahertz atmospheric windows. However, due to the difficulty in balancing high absorption and tunability, the actual manufacturing of most terahertz absorbers usually neglects the integration of electrical tuning, which limits their development of dynamic wave trapping for electronic countermeasure systems. Here, a terahertz stealth metamaterial (TSM) with hierarchical ionotronic architecture is proposed to overcome the tradeoff.

Remote neurostimulation through an endogenous ion channel using a near-infrared light-activatable nanoagonist.

The development of noninvasive approaches to precisely control neural activity in mammals is highly desirable. Here, we used the ion channel transient receptor potential ankyrin-repeat 1 (TRPA1) as a proof of principle, demonstrating remote near-infrared (NIR) activation of endogenous neuronal channels in mice through an engineered nanoagonist. This achievement enables specific neurostimulation in nongenetically modified mice.

Dynamic Characterization of Optical Coherence-Based Displacement-Type Weight Sensor.

Dynamic characteristics play a crucial role in evaluating the performance of weight sensors and are essential for achieving fast and accurate weight measurements. This study focuses on a weight sensor based on optical coherence displacement. Using finite element analysis, the sensor was numerically simulated.

Optical coherence tomography for the early detection of colorectal dysplasia and cancer: validation in a murine model.

Background: There is an urgent need to develop a non-invasive imaging technique for detecting colorectal dysplasia and cancer. Technology for early and real-time microscopic assessments to select the most representative biopsy sites would also be of clinical value. In this study, we explored the sensitivity of optical coherence tomography (OCT) in detecting local lesions to demonstrate its potential for the early detection of colorectal dysplasia and cancer.

Optical coherent tomography to evaluate the degree of inflammation in a mouse model of colitis.

Background: There is an urgent need to develop a noninvasive imaging technique for the diagnosis of early inflammatory lesions or early and real-time microscopic assessment before selecting the most representative biopsy sites.

Methods: In this study, a dextran sulfate sodium colitis model was developed, and intestinal histological damage scores measured the degree of inflammation in colitis. According to these scores, 6 parameters were designed for hematoxylin and eosin (HE) sections based on morphological changes, and 2 parameters were designed for optical coherence tomography (OCT) images to measure submucosal edema by morphological changes to evaluate inflammation degrees in the colon.

High-performance optical coherence velocimeter: theory and applications.

We proposed a high-performance optical coherence velocimeter (OCV) based on broadband optical interference which achieves spatial resolution from interference cancellation or enhancement of different components of the broadband light. There is a challengeable issue for OCV that the interference fringes become blurred when the velocity of detected object is relatively large, hindering the pace of OCV application in high-velocity field. To resolve this, the relationship between blurry coefficient and OCV system parameters (e.

Zein-Paclitaxel Prodrug Nanoparticles for Redox-Triggered Drug Delivery and Enhanced Therapeutic Efficiency.

Prodrug, in which the inactive parent drug with good bioavailability is metabolized into an active drug in the body, is one of the main strategies to target the disease site to improve the drug efficiency and reduce the adverse effects of chemotherapy. Because of the good capability of chemical modification, zein, a plant derived protein, and drugs can be conjugated through environmentally sensitive links to form prodrugs capable of triggered drug release. In this study, a novel prodrug was synthesized using paclitaxel (PTX), zein, and a disulfide linker, and nanoparticles were formed by self-assembly of the prodrug.

Characterization and reactivity of iron based nanoparticles synthesized by tea extracts under various atmospheres.

Bio-synthesis of Fe NPs in inert (nitrogen N-Fe NPs) and oxygen (O-Fe NPs) atmospheres employing green tea extracts was investigated through SEM, EDS, XPS and FT-IR techniques. The particle sizes of N-Fe NPs and O-Fe NPs were confirmed by SEM showing 84.7 ± 11.