Association between depressive symptoms and all-cause and cardiovascular mortality in diabetes patients: A national cohort study.

Background: Depression is a significant psychological burden frequently observed among diabetic patients, and it has been increasingly linked to higher mortality risks, particularly from cardiovascular diseases. Clarifying why depression contributes to these risks is essential for effective intervention strategies.

Methods: This national cohort study utilized data from the National Health and Nutrition Examination Survey (NHANES) (2005-2018), analyzing 4743 diabetic patients.

Dietary Addition of Tributyrin Improved the Production Performance, Antioxidant Ability and Intestinal Health in Weaned Rabbits.

The present study was conducted to investigate the effects of dietary addition of tributyrin on growth performance, antioxidant and intestinal health in weaned rabbits. Weaned Hyla rabbits (35 d, = 1280) of similar body weight were randomly divided into four groups (eight replicates per group, 40 rabbits per replicate), fed diets with 0, 0.1%, 0.

Frailty and depressive symptoms in relation to cardiovascular disease risk in middle-aged and older adults.

As global aging accelerates, frailty and depressive symptoms have emerged as critical contributors to cardiovascular disease (CVD) risk among older adults. However, the dynamic interplay between these factors remains underexplored. Here, we examine the associations among frailty, depressive symptoms, and incident CVD using data from five international cohorts (HRS, CHARLS, SHARE, ELSA, MHAS) involving individuals aged 50 and above.

Sleep disorders accelerate biological aging through depressive symptoms: Evidence from NHANES.

This study investigates the impact of sleep disorders on biological aging, examining the mediating role of depressive symptoms and the moderating effect of a healthy lifestyle. Data were drawn from the National Health and Nutrition Examination Survey (NHANES) for the years 2005-2014, with a sample of 18,862 participants aged 20-79. Biological aging was assessed using the Klemera-Doubal method (KDM-BA), depressive symptoms were measured with the PHQ-9 scale, and lifestyle factors were evaluated based on smoking, alcohol consumption, and physical activity.

Renewable energy reduces domestic depression but increases depression for neighboring countries: evidence of spatial effects from 181 countries worldwide.

Background: Depression poses a significant global public health challenge, affecting millions of people worldwide. The utilization of renewable energy holds potential for improving mental health by reducing air pollution and promoting green spaces.

Purpose: This study aims to investigate the impact of renewable energy use on depression, with a focus on its spatial effects and the mediating roles of air pollution reduction and green space expansion.

China's Healthy City Pilot Policy Improves Physical and Mental Health Outcomes for Middle-Aged and Older Adults: A Quasi-Natural Experiment Based on CHARLS.

Background: Rapid urbanization in China has raised significant public health concerns, particularly regarding residents' physical and mental well-being. Effective interventions are urgently needed to address these issues.

Objective: This study evaluates the impact of China's Healthy City Pilot Policy (HCPP), introduced in 2016, on improving residents' health outcomes and examines demographic differences and mechanisms driving these effects.

Nature connectedness alters the structure of the dehumanization-mental symptoms network: A comparative cross-sectional network analysis.

Background: Dehumanization is often closely linked to mental health issues, connection with nature has the potential to buffer the impact of dehumanization and enhance psychological well-being. This study aims to explore how nature connectedness differs in its influence on the network structure between dehumanization and mental symptoms.

Methods: A network structure model was constructed of dehumanization and mental symptoms based on a sample of 5914.

Weight loss methods and risk of depression: Evidence from the NHANES 2005-2018 cohort.

Background: Weight loss behaviors are increasingly common worldwide. While healthy weight loss methods, such as calorie control and exercise, can improve both physical and mental health, harmful practices-such as extreme dieting and the misuse of diet pills-may contribute to depressive symptoms. Understanding the psychological impact of different weight loss strategies is essential for promoting overall well-being.

Urinary arsenic and depressive symptoms among adults: A moderated mediation analysis of folate and dietary inflammation index.

Background: Few studies have explored the effects of arsenic exposure on depressive symptoms and the underlying mechanisms of its influence on this relationship. This study aimed to assess the impact of urinary arsenic on depressive symptoms and the mediating and moderating roles of folate and dietary inflammation index (DII).

Methods: Cross-sectional data from 9775 participants (≥20 years) in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2020 were used for analysis.

The impact of mold exposure on anxiety symptoms in the older adults: A moderated mediation model based on CLHLS.

Background: Mold exposure is a common environmental issue that can adversely affect health, particularly among older adults. The impact of mold exposure on anxiety symptoms in this population has not been extensively studied.

Objective: This study aims to examine the relationship between mold exposure and anxiety symptoms in older adults, considering the mediating role of cognitive function and the moderating effects of open window ventilation and multivitamin supplementation.

Urban resilience reduces depressive symptoms among middle-aged and elderly adults: A multidimensional analysis based on China longitudinal healthy longevity survey.

With the rapid urbanization and aging population, depression has become a severe public health issue globally, affecting millions of individuals and significantly impacting their quality of life and healthcare costs. Urban resilience refers to a city's ability to absorb, recover, and prepare for future shocks, ensuring sustainable development despite challenges. This study aims to explore the impact of urban resilience on depressive symptoms among middle-aged and elderly adults.

Target-modulated mineralization of wood channels as enzyme-free electrochemical sensors for detecting amyloid-β species.

Alzheimer's disease (AD) is an irreversible brain disorder, which has been found to be associated with neurotoxic amyloid-β oligomers (AβO). The early diagnosis of AD is still a great challenge. Herein, inspired by the hierarchical channel structure of natural wood, we design and demonstrate a low-cost and sensitive wood channel-based fluidic membrane for electrochemical sensing of AβO.

Enantioselective Target Transport-Mediated Nanozyme Decomposition for the Identification of Reducing Enantiomers in Asymmetric Nanochannel Arrays.

Enantioselective identification of chiral molecules is regarded as one of the key issues in biological and medical sciences because of their configuration-dependent effects on biological systems. In this study, we developed an electrochemical platform based on a tandem recognition-reaction zone design in TiO nanochannels for the specific recognition of reducing enantiomers. In this system, MIL-125(Ti) Ti-metal-organic frameworks, grown in TiO nanochannels, provided a homochiral recognition environment postmodification with l-tartaric acid (l-TA); MnO nanosheets possessing both glucose oxidase (GOD)- and peroxidase (POD)-mimicking activities served as the target-reactive zone at the end of the nanochannels.

Metal organic frameworks-in-nanochannels: A tailorable chromatography membrane for isolation of target protein.

Metal-organic frameworks (MOFs) demonstrate strong potential in biosample separation. However, the obtained MOFs powders are unsuitable for recovery techniques in an aqueous solution, especially the challenges of withdrawing MOFs particles and expanding their functions for specific applications. Herein, a general strategy is designed utilizing metal oxide-nanochannel arrays as precursors and templates for in-situ selective growth of MOFs structures.

Target Recognition-Triggered Peroxidase-Mimicking Activity Depression in Homochiral Nanochannels for Identifying Cystine Enantiomers.

Enantioselective identification of chiral molecules is of paramount importance in medical science, biochemistry, and pharmaceutics owing to the configuration-dependent activities of enantiomers. However, the identical physicochemical properties of enantiomers remain challenging in chiral sensing. In this study, inspired by the peroxidase-mimicking activity of Fe(III)-based nanomaterials, an enantioselective artificial architecture is constructed on TiO nanochannels.

Rational design of mesoporous chiral MOFs as reactive pockets in nanochannels for enzyme-free identification of monosaccharide enantiomers.

Monosaccharides play significant roles in daily metabolism in living organisms. Although various devices have been constructed for monosaccharide identification, most rely on the specificity of the natural enzyme. Herein, inspired by natural ionic channels, an asymmetrical MOF-in-nanochannel architecture is developed to discriminate monosaccharide enantiomers based on cascade reactions by combining oxidase-mimicking and Fenton-like catalysis in homochiral mesoporous CuMOF pockets.

Locally superengineered cascade recognition-quantification zones in nanochannels for sensitive enantiomer identification.

As an intriguing and intrinsic feature of life, chirality is highly associated with many significant biological processes. Simultaneous recognition and quantification of enantiomers remains a major challenge. Here, a sensitive enantiomer identification device is developed on TiO nanochannels the design of cascade recognition-quantification zones along the nanochannels.

Long-term average spectrum measures of consecutive snore sounds from different sources determined by drug-induced sleep endoscopy.

Study Objectives: The goal of this study was to investigate the value of the long-term average spectrum in the acoustic analysis of snore sounds arising from different sources in the upper airway.

Methods: Long-term average spectrum was used to analyze sequences of 10 consecutive snore sounds that had been divided into 2 groups, soft-palate type and lateral-wall type, according to the vibration site generating the snore sounds and the patterns of soft tissue collapse in the upper airway as identified by drug-induced sleep endoscopy. We calculated the first spectral peak, mean spectral energy, high-frequency energy, 0-1 kHz spectral energy, 1-5 kHz spectral energy, and 0-1 kHz/1-5 kHz difference from each group and compared the differences between them.

Melanin-gelatin nanoparticles with both EPR effect and renal clearance for PA/MRI dual-modal imaging of tumors.

As cancer nanotherapeutics, the ideal multifunctional nanoparticles not only have the processing ability to accumulate effectively in tumors, but also can be excreted rapidly from the body via renal clearance after effective treatment. Melanin is an endogenous biological material, and gelatin has natural biocompatibility and biodegradability. Such materials are more promising in the development of diagnostic and therapeutic nanoplatform for future clinical translation.