Synergistic Composite Solid Electrolyte Based on Multifunctional Polymer Networks for High-Performance Lithium Metal Batteries.

The advancement of polymer-based solid-state electrolytes (SPEs) is essential for the development of high energy density (ED) and long-operation durability lithium-metal batteries (LMBs). However, conventional poly (ethylene oxide) (PEO)-based electrolytes suffer from insufficient ionic conductivity (IC) at room temperature (RT) and limited capability to suppress lithium (Li) dendrite growth, particularly under high-rate operations. These challenges arise from unfavorable anion-solvate structures, which lead to a reduced Li-ion transference number (LITN) and hinder efficient ion transport.

Design of Antimicrobial Peptides against Carbapenem-Resistant Infections with Enhanced Activity by Nanoformulation.

Carbapenem-resistant (CRAB) has emerged as a critical public health menace. Its resistance to last-resort antibiotics highlights the urgent need for innovative treatment approaches. Antimicrobial peptides (AMPs) are promising candidates to address this challenge.

Flexible Non-Enzymatic Glucose Sensors: One-Step Green Synthesis of NiO Nanoporous Films via an Electro-Exploding Wire Technique.

In this study, we successfully synthesized nickel oxide (NiO) nanoparticles (NPs), i.e., samples , , and , via an environmentally friendly one-step electro-exploding wire technique by employing three distinct voltage levels of 24, 36, and 48 V, respectively.

Discovery of a novel benzimidazole conjugated quinazolinone derivative as a promising SARS-CoV-2 3CL protease inhibitor.

This report presents the design and synthesis of quinazolinone-based derivatives as promising SARS-CoV-2 3CL protease inhibitors. Two novel series, namely, febrifugine analogues 4a-i and quinazolinone conjugated benzimidazoles 9a-c, were successfully synthesized starting from isatoic anhydride. The synthesized quinazolinone derivatives were evaluated for their cytotoxicity against cancer cell lines and SARS-CoV-2 3CL inhibitory activity.

A-LLTO Nanoparticles Embedded Composite Solid Polymer Electrolyte for Room Temperature Operational Li-metal Batteries.

Solid-state batteries (SSBs) have the potential to revolutionize the current energy storage sector. A significant portion of the current development of electric vehicles and the electrification of various appliances relies on Lithium (Li)-ion batteries. However, future energy demands will require the development of stronger and more reliable batteries.

Tunable Nano-Bending Structures of Loosened/Tightened Lassos with Bi-Stable Vibration-Induced Emissions for Multi-Manipulations of White-Light Emissions and Sensor Applications.

The first tunable nano-bending structures of [1]rotaxane containing a single-fluorophoric N,N'-diphenyl-dihydrodibenzo[a,c]phenazine (DPAC) moiety (i.e., [1]RA) are developed as a loosened lasso structure to feature the bright white-light emission [CIE (0.

Intrinsically Stretchable Conductive Self-Healable Organogels for Strain, Pressure, Temperature, and Humidity Sensing.

Intrinsically stretchable conductive self-healable organogels containing poly(lipoic acid), Al ion, tannic acid, and reduced graphene oxide are produced in this report. These noncovalent networks interlocked through physical (hydrogen and coordination) bonds offered high stretchabilities and mechanical strengths as well as fast self-healing behaviors. The optimum organogel-based sensor showed outstanding pressure sensitivities (0.

Controllable Aggregation-Induced Emission and Förster Resonance Energy Transfer Behaviors of Bistable [2] Daisy Chain Rotaxanes for White-Light Emission and Temperature-Sensing Applications.

Bistable [2] daisy chain rotaxanes with respective extended and contracted forms of 2 and 2 containing a blue-emissive anthracene () donor and orange-emissive indandione-carbazole () acceptor were successfully synthesized via click reaction. Tunable-emission bistable [2] daisy chain rotaxanes with fluorescence changes from blue to orange, including bright-white-light emissions, could be modulated by the aggregation-induced emission (AIE) characteristics and Förster resonance energy transfer (FRET) processes through altering water fractions and shuttling processes (i.e.

Quinazolinone-Peptido-Nitrophenyl-Derivatives as Potential Inhibitors of SARS-CoV-2 Main Protease.

The severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2-M) plays an essential role in viral replication, transcription, maturation, and entry into host cells. Furthermore, its cleavage specificity for viruses, but not humans, makes it a promising drug target for the treatment of coronavirus disease 2019 (COVID-19). In this study, a fragment-based strategy including potential antiviral quinazolinone moiety and glutamine- or glutamate-derived peptidomimetic backbone and positioned nitro functional groups was used to synthesize putative M inhibitors.

Dual and sequential locked/unlocked photo-switching effects on FRET processes by tightened/loosened nano-loops of diarylethene-based [1]rotaxanes.

The self-trapping nano-loop structures of [1]rotaxanes exhibited multiple Förster resonance energy transfer (FRET) patterns dual and sequential locking/unlocking of pH-gated and UV exposure processes. As a tightened and constrained nano-loop in the acidic condition, dithienylethene (DTE) unit was locked in the highly bending open form to forbid ring closure upon UV irradiation.

Dual and Sequential Locked/Unlocked Photochromic Effects on FRET Controlled Singlet Oxygen Processes by Contracted/Extended Forms of Diarylethene-Based [1]Rotaxane Nanoparticles.

Manipulations of singlet oxygen ( O ) generations by the integration of both aggregation-induced emission luminogen (AIEgen) photosensitizer and photochromic moieties have diversified features in photodynamic therapy applications. Through Förster resonance energy transfer (FRET) pathway to induce red PL emissions (at 595 nm) for O productions, [1]rotaxane containing photosensitive tetraphenylethylene (TPE) donor and photochromic diarylethene (DAE) acceptor is introduced to achieve dual and sequential locked/unlocked photoswitching effects by pH-controlled shuttling of its contracted/extended forms. Interestingly, the UV-enabled DAE ring closure speeds follow the reversed trend of DAE self-constraint degree as: contracted < extended < noninterlocked forms in [1]rotaxane analogues, thus FRET processes can be adjusted in contracted/extended forms of [1]rotaxane upon UV irradiations.

Designs and Applications of Multi-stimuli Responsive FRET Processes in AIEgen-Functionalized and Bi-fluorophoric Supramolecular Materials.

Materials capable of displaying strong ratiometric fluorescence with Förster resonance energy transfer (FRET) processes have attracted much research interest because of various chemosensor and biomedical applications. This review highlights several popular strategies in designing FRET-OFF/ON mechanisms of ratiometric fluorescence systems. In particular, the developments of organic and polymeric FRET materials featuring aggregation-induced emission-based luminogens (AIEgens), supramolecular assemblies, photochromic molecular switches and surfactant-induced AIE/FRET mechanisms are presented.

Self-healable and anti-freezing ion conducting hydrogel-based artificial bioelectronic tongue sensing toward astringent and bitter tastes.

Numerous efforts have been attempted to mimic human tongue since years. However, they still have limitations because of damages, temperature effects, detection ranges etc. Herein, a self-healable hydrogel-based artificial bioelectronic tongue (E-tongue) containing mucin as a secreted protein, sodium chloride as an ion transporting electrolyte, and chitosan/poly(acrylamide-co-acrylic acid) as the main 3D structure holding hydrogel network is synthesized.

Controllable FRET Behaviors of Supramolecular Host-Guest Systems as Ratiometric Aluminum Ion Sensors Manipulated by Tetraphenylethylene-Functionalized Macrocyclic Host Donor and Multistimuli-Responsive Fluorescein-Based Guest Acceptor.

The novel multistimuli-responsive monofluorophoric supramolecular polymer and pseudo[3]rotaxane consisted of the closed form of nonemissive fluorescein guest along with TPE-based main-chain macrocyclic polymer and TPE-functionalized macrocycle hosts, respectively. By the combination of various external stimuli, these fluorescent supramolecular host-guest systems could reveal interesting photoluminescence (PL) properties in DMF/HO (1:1, v/v) solutions, including bifluorophoric host-guest systems after the complexation of Al ion, i.e.

FRET processes of bi-fluorophoric sensor material containing tetraphenylethylene donor and optical-switchable merocyanine acceptor for lead ion (Pb) detection in semi-aqueous media.

A novel aggregation-induced emission (AIE) structure containing a tetraphenylethene (TPE) unit covalently linked with a merocyanine (MC) unit was synthesized and investigated in semi-aqueous solutions with 90% water fraction. The open-form structure of red-emissive MC unit combined with TPE unit was utilized as a bi-fluorophoric sensor to detect lead(II) ion, which could be transformed from the close-form structure of non-emissive SP unit upon UV exposure. Moreover, the TPE unit as an energy donor with the blue-green photoluminescence (PL) emission at 480 nm was combined with the MC unit as an energy acceptor with the red PL emission at 635 nm.

Efficient FRET Approaches toward Copper(II) and Cyanide Detections via Host-Guest Interactions of Photo-Switchable [2]Pseudo-Rotaxane Polymers Containing Naphthalimide and Merocyanine Moieties.

A supramolecular [2]pseudo-rotaxane containing a naphthalimide-based pillararene host and a spiropyran-based imidazole guest was synthesized and investigated in a semiaqueous solution with 90% water fraction. Upon UV exposure, the close-form structure of nonemissive spiropyran guest could be transformed into the open-form structure of red-emissive merocyanine guest reversibly, which was utilized as a monofluorophoric sensor to detect copper(II) and cyanide ions. Moreover, the naphthalimide host as an energy donor with green photoluminescence (PL) emission at 505 nm was complexed with the merocyanine guest as an energy acceptor with red PL emission at 650 nm in 1:1 molar ratio to generate a [2]pseudo-rotaxane polymer, which was further verified by the diffusion coefficients of DOSY nuclear magnetic resonance (NMR) measurements.

Highly Efficient Förster Resonance Energy Transfer Modulations of Dual-AIEgens between a Tetraphenylethylene Donor and a Merocyanine Acceptor in Photo-Switchable [2]Rotaxanes and Reversible Photo-Patterning Applications.

A series of novel photo-switchable [2]rotaxanes (i.e., and before and after shuttling controlled by acid-base, respectively) containing one spiropyran (SP) unit (as a photochromic stopper) on the axle and two tetraphenylethylene (TPE) units on the macrocycle were synthesized via click reaction.

Multi-Stimuli Responsive FRET Processes of Bifluorophoric AIEgens in an Amphiphilic Copolymer and Its Application to Cyanide Detection in Aqueous Media.

A novel amphiphilic aggregation-induced emission (AIE) copolymer, that is, , consisting of -isopropylacrylamide (NIPAM) as a hydrophilic unit and a tetraphenylethylene-spiropyran monomer () as a bifluorophoric unit is reported. Upon UV exposure, the close form of non-emissive spiropyran (SP) in can be photo-switched to the open form of emissive merocyanine (MC) in in an aqueous solution, leading to ratiometric fluorescence of AIEgens between green TPE and red MC emissions at 517 and 627 nm, respectively, via Förster resonance energy transfer (FRET). Distinct FRET processes of can be observed under various UV and visible light irradiations, acid-base conditions, thermal treatments, and cyanide ion interactions, which are also confirmed by theoretical studies.

Flexible Organic Thin Film Transistors Incorporating a Biodegradable CO-Based Polymer as the Substrate and Dielectric Material.

Employing CO-based polymer in electronic applications should boost the consumption of CO feedstocks and provide the potential for non-permanent CO storage. In this study, polypropylene carbonate (PPC) is utilized as a dielectric and substrate material for organic thin film transistors (OTFTs) and organic inverter. The PPC dielectric film exhibits a surface energy of 47 mN m, a dielectric constant of 3, a leakage current density of less than 10 A cm, and excellent compatibility with pentacene and PTCDI-C8 organic semiconductors.

Exploration of Energy Modulations in Novel RhB-TPE-Based Bichromophoric Materials via Interactions of Cu(2+) Ion under Various Semiaqueous and Micellar Conditions.

Novel bichromophoric materials TR-A and TR-B consisting of an entirely new combination of TPE and RhB units were developed to explore the optimum conditions of energy modulations via pH variation and Cu(2+) interaction at various water contents of CH3CN. Interestingly, TR-A and TR-B, at 60 and 70% water contents, respectively, favored the optimum Cu(2+)-mediated energy modulations from TPE to RhB and thus achieve the brightest orange emissions of free RhB with complete disappearance of aggregation-induced emission (AIE) from TPE. Furthermore, various micellar conditions of triton-X-100, SDS, and CTAB were employed to adjust energy modulations of TR-A and TR-B at high water contents (at 80 and 90%, respectively).

A theranostic nrGO@MSN-ION nanocarrier developed to enhance the combination effect of sonodynamic therapy and ultrasound hyperthermia for treating tumor.

Sonodynamic therapy (SDT), which induces activation of sonosensitizers in cancer cells through ultrasound irradiation, has emerged as an alternative and promising noninvasive therapeutic approach to kill both superficial and deep parts of tumors. In this study, mesoporous silica (MSN) grown on reduced graphene oxide nanosheet (nrGO) capped with Rose Bengal (RB)-PEG-conjugated iron-oxide nanoparticles (IONs), nrGO@MSN-ION-PEG-RB, was strategically designed to have targeted functionality and therapeutic efficacy under magnetic guiding and focused ultrasound (FUS) irradiation, respectively. The singlet oxygen produced by ultrasound-activated RB and the ultrasound-induced heating effect was enhanced by rGO and IONs, which improved the cytotoxic effect in cancer cells.

A plug-and-measure diagnostic tool for flux, resolution and beam size of a soft X-ray beamline.

A compact multi-functional diagnostic tool has been installed for commissioning beamlines at the Taiwan Light Source. For a photon beam, the instrument can measure the photon flux, energy resolution and beam size, consecutively with a photodiode or gold mesh, a windowless gas cell and a movable fluorescence screen viewport. Two gratings with ruling densities of 350 and 1000 lines mm(-1) and dispersing photons of energies from 80 to 1200 eV were calibrated with a photon flux of 10(11) photon s(-1) at slit openings of 50 µm × 50 µm; a maximum resolving power of greater than 10000 was certified with an absorption spectra of gaseous samples.

Self-assembly of tetraphenylethene-based [2]catenane driven by acid-base-controllable molecular switching and its enabled aggregation-induced emission.

A novel [2]catenane 2-C based on the tetraphenylethene (TPE) and orthogonal H-bonded cleft was successfully constructed. VT-NMR and TEM measurements demonstrate that 2-C could be self-assembled to induce an enabled aggregation-induced emission (AIE) in aqueous solution and solid state owing to its TPE unit as well as present unique acid-base controllable and reversible supramolecular self-assembled nanosuperstructures by interplay of a wide range of noncovalent interactions.