Psychometric Validation of EQ-5D-5L in Individuals With Chronic Spinal Cord Injury in China.

Objectives: The EQ-5D is a brief measure for assessing health-related quality of life (HRQoL), but chronic spinal cord injury (CSCI) related psychometric evaluation of the EQ-5D-5L has not been explored. We conducted a validation study on the Chinese version of the EQ-5D-5L for individuals with CSCI in China.

Methods: A cross-sectional study was conducted in the Shanghai Sunshine Rehabilitation Center.

The network and interactive pattern of social adjustment and psychological symptoms in patients with spinal cord injury: a network analysis.

Background: The network approach offers a novel framework for conceptualizing depression, anxiety and social adaptability as causal systems, which helps in understanding what may be relevant targets for treatment.

Objective: To determine the network structure and interaction patterns of social adjustment and psychological symptoms in patients with spinal cord injury (SCI).

Methods: A cross-sectional patient-reported study was conducted using an online questionnaire survey disseminated from February to April 2023.

Trunk Neuromuscular Impairment Following Spinal Cord Injury: Insights into Bidirectional and Nonlinear Corticomuscular Coupling.

Spinal cord injury (SCI) leads to disruptions in trunk motion patterns due to alterations in trunk neuromuscular control, with these changes remaining incompletely understood. This study investigates how SCI alters bidirectional and nonlinear trunk corticomuscular coupling (CMC). Seventeen SCI individuals and eighteen healthy controls experienced unexpected sagittal seated perturbations at 70% of their maximal acceptable intensity.

Practical Interface Engineering between Perovskite and Carbon Electrode in Regular Carbon-Based Perovskite Solar Cells.

Despite the continuous growth in power conversion efficiencies (PCEs) of hole transport layer-free carbon-based perovskite solar cells (HTL-free C-PSCs) due to their enhanced stability and low-cost structure, their performance still lags behind the Shockley-Queisser limit (∼33%) for CHNHPbI PSCs and even regular PSCs with HTL and metal counter electrodes (26.9%). This discrepancy primarily stems from poor physical contact at the perovskite/carbon interface, energy band alignment mismatch, and the inability of the carbon electrode (CE) to reflect incident light.

The trunk segmental motion complexity and balance performance in challenging seated perturbation among individuals with spinal cord injury.

Background: Motion complexity is necessary for adapting to external changes, but little is known about trunk motion complexity during seated perturbation in individuals with spinal cord injury (SCI). We aimed to investigate changes following SCI in trunk segmental motion complexity across different perturbation directions and how they affect postural control ability in individuals with SCI.

Methods: A total of 17 individuals with SCI and 18 healthy controls participated in challenging sagittal-seated perturbations with hand protection.

Proteus faecis: a potentially pathogenic bacterium isolated from the freshwater Yangtze finless porpoise.

Proteus faecis is a gram-negative facultative anaerobic rod-shaped bacterium capable of swarming motility. It has been isolated from numerous sources such as humans, animals, and refuse and is considered potentially pathogenic towards humans. In this study, bacteria were isolated from the blowhole of a Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis; YFP) living in captivity in China.

Modulation of virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex.

Unlabelled: The injectisome encoded by pathogenicity island 2 (SPI-2) had been thought to translocate 28 effectors. Here, we used a proteomic approach to characterize the secretome of a clinical strain of invasive non-typhoidal serovar Enteritidis that had been mutated to cause hyper-secretion of the SPI-2 injectisome effectors. Along with many known effectors, we discovered the novel SseM protein.

[BMP][BF]-Modified CsPbIBr Solar Cells with Improved Efficiency and Suppressed Photoinduced Phase Segregation.

With the rapid progress in a power conversion efficiency reaching up to 26.1%, which is among the highest efficiency for single-junction solar cells, organic-inorganic hybrid perovskite solar cells have become a research focus in photovoltaic technology all over the world, while the instability of these perovskite solar cells, due to the decomposition of its unstable organic components, has restricted the development of all-inorganic perovskite solar cells. In recent years, Br-mixed halogen all-inorganic perovskites (CsPbI3-xBrx) have aroused great interests due to their ability to balance the band gap and phase stability of pure CsPbX3.

Solvothermal synthesis of SnO nanoparticles for perovskite solar cells application.

Perovskite solar cells show great potential application prospects in the field of solar cells due to their promising properties. However, most perovskite solar cells that exhibit excellent photovoltaic performance typically require a carrier transport layer that necessitates a high-temperature annealing process. This greatly restricts the scalability and compatibility of perovskite solar cells in flexible electronics.

Tumor cell-derived exosomes mediating hsa_circ_0001739/lncRNA AC159540.1 facilitate liver metastasis in colorectal cancer.

Background: The current study probed into how tumor cell-derived exosomes (Exos) mediated hsa_circ_0001739/lncRNA AC159540.1 to manipulate microRNA (miR)-218-5p/FTO-N6-methyladenosine (m6A)/MYC signal axis in liver metastasis in colorectal cancer (CRC).

Methods: hsa_circ_0001739 and lncRNA AC159540.

Validation study of the Chinese version of the Community Integration Questionnaire-Revised for individuals with spinal cord injury in Mainland China.

To validate the Chinese version of the Community Integration Questionnaire-Revised (CIQ-R-C) for individuals with spinal cord injury. Cross-sectional study. Shanghai Sunshine Rehabilitation Center.

Characteristics of corticomuscular coupling during wheelchair Tai Chi in patients with spinal cord injury.

Background: Wheelchair Tai Chi (WCTC) has been proved to have benefits for the brain and motor system of spinal cord injury (SCI) patients. However, the characteristics of corticomuscular coupling during WCTC are scarcely known. We aimed to investigate changes following SCI on corticomuscular coupling, and further compare the coupling characteristics of WCTC with aerobic exercise in SCI patients.

Recruitment of transcription factor ETS1 to activated accessible regions promotes the transcriptional program of cilia genes.

Defects in cilia genes, which are critical for cilia formation and function, can cause complicated ciliopathy syndromes involving multiple organs and tissues; however, the underlying regulatory mechanisms of the networks of cilia genes in ciliopathies remain enigmatic. Herein, we have uncovered the genome-wide redistribution of accessible chromatin regions and extensive alterations of expression of cilia genes during Ellis-van Creveld syndrome (EVC) ciliopathy pathogenesis. Mechanistically, the distinct EVC ciliopathy-activated accessible regions (CAAs) are shown to positively regulate robust changes in flanking cilia genes, which are a key requirement for cilia transcription in response to developmental signals.

Hole transport free carbon-based high thermal stability CsPbIBr solar cells with an amorphous InGaZnO electron transport layer.

Due to their low cost, tunable band gap and excellent thermostability, all-inorganic halide perovskites CsPbX (X = Br, I) have become a kind of promising photovoltaic material. However, compared to the organic-inorganic hybrid perovskite solar cells, the performance of CsPbX solar cells still needs to be improved. In this work, for the first time, we applied the sol-gel derived amorphous InGaZnO film as electron transport layers (ETLs) in CsPbX-based devices.

Biofilm formation, antimicrobial assay, and toxin-genotypes of Clostridium perfringens type C isolates cultured from a neonatal Yangtze finless porpoise.

This is a culture-dependent study with the objective of pure culturing and characterizing pathogenic bacteria from the blowhole, lung, stomach and fecal samples of a neonatal crucially endangered Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis) that died 27 days after birth. Bacteria were inoculated using a swab onto blood and MacConkey agar plates and representative isolates were identified through 16S rRNA gene sequence analysis. A total of three Clostridium perfringens type C strains from the fecal samples were isolated.

The Prevalence of and Factors Associated With Anxiety and Depression Among Working-Age Adults in Mainland China at the Early Remission Stage of the Coronavirus 2019 Pandemic.

Background: The Coronavirus 2019 (COVID-19) outbreak has led to a considerable proportion of adverse psychological symptoms in different subpopulations. This study aimed to investigate the status of anxiety and depression and their associated factors in the adult, working-age population in Mainland China at the early remission stage of the COVID-19 pandemic.

Methods: An online study was conducted among 1,863 participants in 29 provinces in Mainland China from March 23 to 31, 2020.

HDAC3 inhibition improves urinary-concentrating defect in hypokalaemia by promoting AQP2 transcription.

Aim: This study investigated whether enhanced histone acetylation, achieved by inhibiting histone deacetylases (HDACs), could prevent decreased aquaporin-2 (AQP2) expression during hypokalaemia.

Methods: Male Wistar rats were fed a potassium-free diet with or without 4-phenylbutyric acid (4-PBA) or the selective HDAC3 inhibitor RGFP966 for 4 days. Primary renal inner medullary collecting duct (IMCD) cells and immortalized mouse cortical collecting duct (mpkCCD) cells were cultured in potassium-deprivation medium with or without HDAC inhibitors.

Adequate Silicone Oil Tamponade by Utilizing the Space of Anterior Segment for Complicated Retinal Detachment: Technique, Efficacy, and Safety.

Purpose: To evaluate the efficacy and safety of adequate silicone oil (SO) tamponade procedure in patients with complicated retinal detachment.

Methods: Thirty-one eyes in 31 patients were enrolled in this prospective case series. Adequate SO tamponade was performed by injecting the SO into the vitreous cavity and the entire anterior chamber, followed by posterior capsulotomy and inferior peripheral iridotomy.

GSK-3β inhibitor TDZD-8 prevents reduction of aquaporin-1 expression via activating autophagy under renal ischemia reperfusion injury.

Renal ischemia/reperfusion (I/R) injury is a main cause of acute kidney injury (AKI). Aquaporin (AQP)-1 water channel in the kidney is critical for the maintenance of water homeostasis and the urinary concentrating ability. Increasing evidence supports an important role of autophagy in the pathogenesis of AKI induced by renal I/R.

Activation of TGR5 restores AQP2 expression via the HIF pathway in renal ischemia-reperfusion injury.

Renal ischemia-reperfusion (I/R) injury is associated with markedly reduced protein expression of aquaporins (AQPs). Membrane G protein-coupled bile acid receptor-1 (TGR5) has shown protective roles in some kidney diseases. The purpose of the current study was to investigate whether activation of TGR5 prevented the decreased protein expression of AQPs in rodents with renal I/R injury and potential mechanisms.

Effects of 16-Form Wheelchair Tai Chi on the Autonomic Nervous System among Patients with Spinal Cord Injury.

Objective: This study aims to investigate the effects of 16-form Wheelchair Tai Chi (WCTC16) on the autonomic nervous system among patients with spinal cord injury (SCI).

Methods: Twenty patients with chronic complete thoracic SCI were recruited. Equivital life monitoring system was used to record and analyze heart rate variability (HRV) of patients for five minutes before and after five consecutive sets of WCTC16, respectively.