Waste Manag
August 2025
Microplastic contamination has emerged as one of the most pressing environmental challenges of our time. While extensive research has been conducted on microplastics in aquatic ecosystems, there remains a significant knowledge gap regarding their presence and impact in terrestrial environments, particularly in agricultural soils, despite microplastic contamination on land being 4 to 23 times higher than in aquatic systems. These soils are increasingly polluted with microplastics from various sources, including plastic mulch films, organic amendments, irrigation, and atmospheric deposition.
View Article and Find Full Text PDF3-methylcrotonyl-CoA carboxylase (3-MCC) deficiency (3-MCC-D) is an autosomal recessive disorder with a variable phenotype. Reduced 3-MCC enzyme activity results in impaired leucine metabolism causing, for example, metabolic acidosis, ketotic hypoglycaemia and carnitine deficiency. The spectrum of clinical presentation is wide, ranging from severe early-onset presentations to incidental findings in asymptomatic individuals.
View Article and Find Full Text PDFMusa paradisiaca and Musa sapientum are among the most prevalent medicinal plants of the genus Musa (Musaceae family) that have therapeutic potential, as indicated by preclinical evidence, against Diabetes mellitus, hypercholesterolemia, microbial infections, hyperlipidemia, inflammation, and oxidative stress. Over the past few decades, both Musa species have been utilized in ethnomedicinal practices to manage symptoms of diarrhea, epilepsy, diabetes, dysentery, ulcers, and hair loss, without a clear understanding of their mode of action and the phytochemicals responsible for these effects. Different plant parts (roots, fruits, peels, stems, bracts, flowers, and inflorescences) contain numerous phytochemicals, such as flavonoids, alkaloids, saponins, essential oils, vitamins, gallic acid, syringin, and caffeic acid, which are responsible for their pharmacological properties.
View Article and Find Full Text PDFThis paper presents an advanced cascaded control scheme for load frequency regulation in multi-area power systems incorporating renewable energy sources (RES) and electric vehicles (EVs). The proposed design (Model predictive control cascaded with one plus proportional-integral control cascaded with tilt control in parallel with one plus fractional-order integral derivative controller (MPC-((1+PI)-(T+(1+ID)))) combines predictive, tilt, and fractional-order dynamics to improve adaptability and robustness under uncertainties. Controller parameters are tuned using the Lyrebird Optimization Algorithm (LOA), ensuring fast convergence and effective global search.
View Article and Find Full Text PDFHeliyon
March 2025
[This retracts the article DOI: 10.1016/j.heliyon.
View Article and Find Full Text PDFObesity and type 2 diabetes mellitus commonly coexist with heart failure (HF) and may contribute to the pathogenesis of HF with preserved ejection fraction. With progression in management therapies for HF with preserved ejection fraction, the mechanism behind beneficial actions of finerenone and semaglutide remains enigmatic. For decades, the cardiorenal protective effects of aldosterone blockage in patients with chronic kidney disease have been of significant interest.
View Article and Find Full Text PDFThe preservation of stability is essential for the efficient and reliable functioning of the electrical transmission system. Frequency oscillations are prevalent in interconnected power systems (IPS) and may lead to instability; therefore, it is crucial to monitor and examine them meticulously. Effective frequency management is essential for regulating frequency output in an interconnected smart power system (ISPS) that includes renewable energy sources (RESs), redox flow batteries (RFBs) and static synchronous series compensators (SSSCs).
View Article and Find Full Text PDFJ Appl Biomater Funct Mater
April 2025
Hemicelluloses are promising candidates for synthesizing nanosystems for potential biomedical and photocatalytic applications. Glucuronoxylan (hemicellulose)-capped manganese oxide nanoparticles (GX-MnO NPs) were synthesized from quince ( M.) seed hydrogel.
View Article and Find Full Text PDFThe interactional nexus of microplastics (MPs) and organic matter (OM) can subtly disrupt the delicate balance of soil ecosystems, influencing nutrient dynamics, biodiversity, and overall soil health. To explore this complex interplay between MPs and OM concerning several perspectives, a comprehensive keyword search was conducted across key scientific databases, and the retrieved data was curated according to the PRISMA guidelines to reflect the objectives. Several studies have highlighted that organic-based inputs, such as manures, composts, and sewage sludge, widely used for soil amendment, are potential sources of MPs to soil contamination.
View Article and Find Full Text PDFPurpose: The potential use of gold nanoparticles (AuNPs) in healthcare research has increased dramatically in recent years, owing to advancements in their synthesis techniques, including green synthesis. Although is a popular medicinal plant that harbors many bioactive phytochemicals in various parts of the world, the green synthesis of AuNPs using this precious plant is still under investigation. Therefore, this study aimed to explore the green synthesis of AuNPs from Thunberg leaves (CTT-AuNPs) and their antibacterial and cytotoxic properties.
View Article and Find Full Text PDFThe current study assessed the wound healing potential of Bergenia ciliata (BC) extract, BC-loaded Salvia hispanica hydrogel (CH-BC) and Bergenia ciliata nanoparticles (NPs)-loaded Salvia hispanica hydrogel (CH-BC AgNPs/NPs-loaded hydrogel) using in vitro and in vivo studies. The prepared hydrogel and its components were analyzed using UV-visible spectrophotometry (UV-vis), scanning electron microscopy (SEM), dynamic light scattering (DLS) analysis/particle size analyzer (PSA), zeta potential, fourier transform infrared spectrometry (FT-IR), and x-ray diffraction (XRD). Peaks and peak shifts at 450-460, 250-260, and 270-280 nm in UV-vis and FT-IR (500-4000 cm) confirmed extract loading and various functional group presence.
View Article and Find Full Text PDFJ Reprod Immunol
June 2025
Endometritis is a significant cause of infertility in mare. Some infectious agents disrupt the endometrium's innate immune system, resulting in a prolonged systemic inflammatory response that circulates via the blood or cellular degeneration, which ultimately leads to endometritis from bacterial endotoxins. Numerous biological processes use various small, non-coding RNA molecules called MicroRNAs.
View Article and Find Full Text PDFLead (Pb), a highly toxic heavy metal, poses a significant global health risk, particularly to children. Widely used in paint manufacturing for its remarkable corrosion-resistance properties Pb exposure has been linked to severe health issues, including reduced neurotransmitter levels, organ damage, potentially leading to death in extreme cases. Children Are particularly vulnerable, with Pb toxicity primarily affecting the brain, reproductive, kidneys, and cardiovascular systems.
View Article and Find Full Text PDFCold atmospheric pressure plasma (CAPP) comprises an ensemble of ionized gas, neutral particles, and/or reactive species. Electricity is frequently used to produce CAPP via a variety of techniques, including plasma jets, corona discharges, dielectric barrier discharges, and glow discharges. The type and flow rates of the carrier gas(es), temperature, pressure, and vacuum can all be altered to control the desired properties of the CAPP.
View Article and Find Full Text PDFThe use of plant seed-based hydrogels to design drug delivery systems (DDSs) has increased due to their swellable, pH-responsive, biocompatible, biodegradable, and non-toxic nature. Herein, the chia seeds hydrogel (CSH) was extracted through an aqueous extraction method to explore its pH and salt-responsive swelling behavior and sustained release potential. The CSH was characterized using Fourier transform infrared (FT-IR) and solid-state cross-polarization magic angle spinning carbon-13 nuclear magnetic resonance (solid/state CP-MAS C/NMR) spectra.
View Article and Find Full Text PDFThe present review is novel as it discusses the main findings of researchers on the topic and their implications, as well as highlights the emerging research in this particular area and its future prospective. The seeds of Flax (Linum usitatissimum) extrude mucilage (FSM) that has a diverse and wide range of applications, especially in the food industry and as a pharmaceutical ingredient. FSM has been blended with several food and dairy products to improve gelling ability, optical properties, taste, and user compliance.
View Article and Find Full Text PDFPakistan is facing energy crises due to localized shortages, market manipulation, infrastructure disruption, rising demand, governance issues, climate and geopolitical events. In this situation Demand Side Management (DSM) is a promising solution to overcome the problem of energy crises. DSM strategy helps to manage consumer demand through energy conservation rather than to addition of new power capacity.
View Article and Find Full Text PDFHeliyon
June 2024
In power systems, load frequency control (LFC) matters significantly to achieve stability. Dealing with the fluctuations in the frequency of a multi-area power system becomes more challenging by incorporating additional energy resources. In this research, a multi-area power system is built by integrating thermal power systems with photovoltaic (PV) cells, wind turbines, and electric vehicles (EV).
View Article and Find Full Text PDFMucilage is a gelatinous mixture of polysaccharides secreted from the seed coat and/or pericarp of many plant seeds when soaked in water. Mucilage affected seed germination while maintaining hydration levels during scarcity. Cydonia oblonga (quince) seeds are natural hydrocolloids extruding biocompatible mucilage mainly composed of polysaccharides.
View Article and Find Full Text PDFMimosa pudica (MP) is an ornamental plant due to seismonastic movements that close leaves and fall petioles in response to touch, wind, light, heat, cold, and vibration. The seeds of MP secrete smart, biocompatible, and non-toxic mucilage that has captivated researchers due to its widespread use in various fields such as pharmaceuticals and biotechnology. The mucilage is responsive to pH, salt solutions, and solvents and acts as a binder in tablet formulations for targeted drug delivery.
View Article and Find Full Text PDFCurr Top Med Chem
July 2025
Berbamine (Ber) is an active medicinal bisbenzylisoquinoline alkaloid, which is usually obtained from different plants of the genus (family ) and is used to cure various disorders in traditional Chinese and Ayurvedic systems of medicine. Numerous and studies revealed the apoptotic and cytotoxic potential of Ber against different cell lines (SMMC-7721, A549, MDA-MB-231, and K562) by upregulating pro-apoptotic (Bax, p53) and downregulating anti-apoptotic (Bcl-2, survivin) proteins. Other pharmacological attributes ascribed to Ber included cardioprotective, anti-diabetic, anti-inflammatory, antimalarial, antioxidant, anti-hypercholesterolemic, and anti-allergic.
View Article and Find Full Text PDFThe current study reports the synthesis of silver nanoparticles (Ag NPs) using a polar extract of leaves. Various analytical techniques, like UV-Vis spectrophotometry, FT-IR spectroscopy, XRD, SEM, and EDX were employed for characterisation. These techniques confirmed the stability of Ag NPs in solution and endorsed the interaction between different groups and Ag, crystal phase, surface morphology, and size of Ag NPs.
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