Association between long-term visit-to-visit resting heart rate variability and cognitive decline: evidence from two national cohorts.

Background: Cognitive impairment is a major public health problem. This study aimed to examine the association between long-term visit-to-visit resting heart rate variability (RHRV) and cognitive dysfunction among the general population.

Methods: Data was derived from the Health and Retirement Study (HRS) and the China Health and Retirement Longitudinal Study (CHARLS).

Association between adverse childhood experiences and long-term blood pressure variability: Insights from a pooled analysis.

Background: The association between adverse childhood experiences (ACEs) and long-term blood pressure variability (BPV) remains unexamined. This study aimed to identify the longitudinal association between ACEs and BPV, and explore the potential modification effect by using a pooled analysis.

Methods: Participants with complete information from the Health and Retirement Study (HRS), the English Longitudinal Study of Ageing (ELSA), and the China Health and Retirement Longitudinal Study (CHARLS) were included.

Adverse childhood experiences and cardiometabolic biomarkers: A causal analysis.

Background: The associations between adverse childhood experiences (ACEs) and cardiometabolic biomarkers need to be further studied. Our objective was to investigate whether ACEs are causally associated with cardiometabolic biomarkers using observational study and two-sample Mendelian randomization (MR) analysis.

Methods: The China Health and Retirement Longitudinal Study (CHARLS) data from 2014 to 2015 was used in the observational study.

Association between road traffic noise exposure and heart failure: A systematic review and meta-analysis of prospective cohort studies.

Objectives: To examine the relationship between road traffic noise exposure and heart failure.

Study Design: A systematic review and meta-analysis was conducted.

Methods: We systematically searched eight databases (PubMed, Embase, Scopus, Cochrane, Web of Science, CNKI, Wanfang Data, and Chinese Biomedical Literature Database) through July 2024 to identify cohort studies on road traffic noise exposure and heart failure according to a priori inclusion criteria.

DNA methylation in the association between pesticide exposures and type 2 diabetes.

Background: Numerous epidemiological studies have found that pesticide exposure is associated with the incidence of type 2 diabetes (T2D); however, the underlying mechanisms remain unknown. DNA methylation may play a role in this process.

Aim: To identify the genes associated with pesticide exposure and T2D by reviewing the current literature.

Environment-wide association study of cardiovascular and all-cause mortality: Analysis of the National Health and Nutrition Examination Survey, 1999-2018.

Environmental toxicants are increasingly suspected to influence cardiovascular (CV) and all-cause mortality, but previous studies mostly focused on one or a few chemicals. We examined the associations of a wide array of environmental chemicals with CV and all-cause mortality using an exposome-wide approach and the potential mediating role of inflammation in these associations. Data from the National Health and Nutrition Examination Survey (1999-2018) were randomly 60:40 split into a training set and a test set.

Mapping environmental noise of Guangzhou based on land use regression models.

Background: Environmental noise seriously affects people's health and life quality, but there is a scarcity of noise exposure data in metropolitan cities and at nighttime, especially in developing countries.

Objective: This study aimed to assess the environmental noise level by land use regression (LUR) models and create daytime and nighttime noise maps with high-resolution of Guangzhou municipality.

Methods: A total of 100 monitoring sites were randomly selected according to population density.

Association between prescription opioid use and heart failure: Cohort studies and Mendelian randomization analysis.

Background: Prescription opioid use (POU) has been shown to lead to cardiovascular disease (CVD), but its association with heart failure has not been well studied. We investigated the potential causal association between POU and HF using cohort studies and Mendelian Randomization (MR) analysis.

Methods: Initially, we examined the longitudinal association between POU and HF using the data from the Health and Retirement Study (HRS) and the UK biobank.

Long-Term Visit-to-Visit Blood Pressure Variability and Cognitive Decline Among Patients With Hypertension: A Pooled Analysis of 3 National Prospective Cohorts.

Background: A limited number of studies investigated the association between blood pressure variability (BPV) and cognitive impairment in patients with hypertension. This study aimed to identify the longitudinal association between BPV and cognitive decline and the role of blood pressure (BP) control in this association.

Methods And Results: Participants with hypertension from the HRS (Health and Retirement Study), the ELSA (English Longitudinal Study of Ageing), and the CHARLS (China Health and Retirement Longitudinal Study) were included.

Living alone and the risk of depressive symptoms: a cross-sectional and cohort analysis based on the China Health and Retirement Longitudinal Study.

Background: There were a few studies that examined the longitudinal association between living alone and depressive symptoms, and the vast majority of them were conducted in patients with certain diseases, such as heart failure, cancer, and glaucoma. This study aimed to examine the association between living alone and depressive symptoms in a large representative older Chinese population.

Methods: The China Health and Retirement Longitudinal Study (CHARLS) data from 2015 to 2018 were used.

The objectively measured walking speed and risk of hypertension in Chinese older adults: a prospective cohort study.

This study aims to investigate the longitudinal association between objectively measured walking speed and hypertension and to explore the potential effect modification of obesity on this association in Chinese older adults. The data from the Chinese Health and Retirement Prospective Cohort Study (CHARLS) during 2011-2015 was used. Walking speed was assessed by measuring the participants' usual gait in a 2.

Associations of pyrethroid exposure with skeletal muscle strength and mass.

This study aimed to examine the associations of pyrethroid exposure with handgrip strength and skeletal muscle mass and potential modification effects in US adults. The data from the National Health and Nutrition Examination Survey was used. Handgrip strength was determined with a handgrip dynamometer, and we quantified muscle mass by using the appendicular skeletal muscle index (ASMI).

Expert consensus on computed tomography-assisted three-dimensional-printed coplanar template guidance for interstitial permanent radioactive I seed implantation therapy.

Interstitial permanent radioactive seed implantation delivers a high local dose to tumors and sharply drops off at surrounding normal tissues. Radioactive seeds implanted via ultrasound or computed tomography (CT) guidance are minimally invasive and facilitate quick recovery. Transrectal ultrasound-guided I seed implantation assisted by a transperineal plane template is standard for early-stage prostate carcinoma, with a highly consistent target volume dose distribution.

Clinical application of planar puncture template-assisted computed tomography-guided percutaneous biopsy for small pulmonary nodules.

Aims: The aims of this study were to evaluate the clinical application of planar puncture template (PPT) in computed tomography (CT)-guided percutaneous needle lung biopsy.

Subjects And Methods: A total of 56 patients with small pulmonary nodules who received CT-guided percutaneous lung biopsy assisted by PPT were included in the study. Five steps were included in the study: fixing position, CT scanning and designing needle pathway, installing navigation system and template, puncturing fixation needle, and performing biopsy needle insertion and biopsy.

Percutaneous computed tomography-guided permanent I implantation as therapy for pulmonary metastasis.

Purpose: To evaluate intermediate-term outcomes after computed tomography (CT)-guided radioactive I seed implantation (CTRISI), and to determine prognostic variables associated with outcomes in patients with pulmonary metastases.

Material And Methods: Thoracic surgeons evaluated and performed implantation of I radioactive seeds under CT guidance or combined with surgical resection. Patients were monitored in the thoracic surgery clinic for recurrence and survival.

Expert consensus statement on computed tomography-guided I radioactive seeds permanent interstitial brachytherapy.

The aim of this study is to develop expert consensus statement for recommendations of patient selection criteria, prescription dose, and procedure of computed tomography (CT)-guided I radioactive seeds permanent interstitial brachytherapy. Members of Chinese medical association radiation oncology branch, Chinese medical association radiation therapy professional committee, Chinese cancer society minimally invasive surgery branch seed therapy group, Chinese geriatric cancer society minimally invasive surgery branch, Beijing medical association radiation oncology professional committee, China northern radioactive seeds brachytherapy group formed a committee, which consists of physician members who come from the department of radiation oncology, surgery, intervention, internal medicine, ultrasound, and nuclear medicine. The leader of the group organized experts to write the first draft based on clinical experience and literature review and then sent the draft to the commissioner for consultation, finally reached a consensus.

I inhibited the NSCLC both in vivo and in vitro.

Lung cancer is the main reason of cancer-linked death all over the world. Non-small cell lung cancer (NSCLC) patients always have an extremely poor prognosis. It is urgent to find novel treating methods.

Implantation of computed tomography-guided Iodine-125 seeds in combination with chemotherapy for the treatment of stage III non-small cell lung cancer.

Purpose: We investigated the role of computed tomography (CT)-guided Iodine-125 (I) seed implantation in combination with chemotherapy for the treatment of stage III non-small cell lung carcinoma (NSCLC).

Material And Methods: The data from 182 patients with stage III NSCLC who were treated with radioactive I seed implantation between June 2002 and June 2009, and who received sequential platinum-based combination chemotherapy using the most common combination of platinum and gemcitabine, were retrospectively reviewed. The 182 patients received a prescribed dose of 110.

All-fiber mode converter based on long-period fiber gratings written in few-mode fiber.

We investigated an all-fiber mode converter based on long-period fiber gratings (LPFGs) written in the few-mode fiber. Mode conversion between the fundamental core mode and different higher-order core modes (LP, LP, and LP modes) can be realized via a single LPFG with an efficiency of 99% at the resonance wavelength. Moreover, optimized mode conversion between the LP and LP modes can be realized by cascading two LPFGs with different grating pitches.

Expert consensus workshop report: Guideline for three-dimensional printing template-assisted computed tomography-guided I seeds interstitial implantation brachytherapy.

Radioactive 125I seeds (RIS) interstitial implantation brachytherapy has been a first-line treatment for early-stage cancer of the prostate gland. However, its poor accuracy and homogeneity has limited its indication and hampered its popularization for a long time. Intriguingly, scholars based in China introduced computed tomography (CT)-guided technology to improve the accuracy and homogeneity of RIS implantation and broadened the indications.