Publications by authors named "Frank K Wacker"

Background: This study aimed to evaluate the imaging performance and diagnostic value of a photon-counting detector (PCD) computed tomography (CT) compared to an energy-integrating detector (EID) and flat panel detector (FPD) for cadaveric wrist arthrographies.

Methods: Following ethics committee approval, ten cadaveric wrists were injected with diluted iodinated contrast agent. CT arthrographies using PCD-, EID-, and FPD-CT were performed.

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In clinical MRI-guided interventions, the lack of high-quality peripheral equipment and specialized interventional MRI systems often necessitates delegating real-time control of MRI scanners to an assistant. We proposed a voice-based interaction system powered by large language models that enabled hands-free natural language control of MRI scanners. The system leveraged multi-agent collaboration driven by large language models to execute scanner functionalities, including sequence execution, parameter adjustment, and scanner table positioning.

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To evaluate image-guided pain therapies on the spine based on data collected in the DeGIR quality assurance (QS) registry for the year 2021, in order to analyze the radiological care situation in Germany.A total of 28915 interventions were analyzed from the DeGIR registry's documented clinical and procedural data for pain management procedures in 2021. The focus was on spine-related therapies, examining the type, location, and methodology of the applied treatments as well as any complications that occurred.

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The increasing number of women working in medical surgical professions involving ionizing radiation creates new challenges for the safety of both pregnant and breastfeeding employees and the management of prenatal radiation exposure. The aim of this manuscript is to discuss the biological effects of loosely-ionizing radiation, evaluate the associated risks, and discuss the principles of German radiation protection law in the context of pregnancy and breastfeeding.To assess the effects of prenatal radiation exposure, we reviewed relevant sources such as reports from the German Commission on Radiological Protection, United Nations Scientific Commission on Effects of Atomic Radiation (UNSCEAR), and publications from the International Commission on Radiological Protection (ICRP).

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Background Although measurable organic dysfunctions are frequently absent in pediatric patients with post-COVID-19 condition (PCC), this condition adversely affects quality of life. Free-breathing phase-resolved functional lung (PREFUL) MRI may be useful for assessing lung function in pediatric patients with PCC. Purpose To detect lung changes in children and adolescents with PCC compared with healthy control participants using PREFUL MRI.

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Objective: Respiratory motion can affect image quality and thus affect the diagnostic accuracy of CT images by masking or mimicking relevant lung pathologies. CT examinations are often performed during deep inspiration and breath-hold to achieve optimal image quality. However, this can be challenging for certain patient groups, such as children, the elderly, or sedated patients.

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Article Synopsis
  • * The survey revealed significant disparities between men and women, such as fewer women in leadership roles, higher rates of part-time work among female physicians, and a perception that women face more challenges in entering the field and balancing work-family commitments.
  • * The findings suggest a need for improved support measures, including flexible work schedules and better childcare options, to promote gender equality and attract young talent in the profession.
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Objectives: The aim of this study was to evaluate the impact of a prototype grid with a 29:1 ratio (r29) and a 15:1 (r15) grid on the image quality (IQ) and radiation dose in abdominal angiography.

Materials And Methods: Six typical abdominal angiographic image scenarios were created in 4 pigs. Polymethylmethacrylate and aluminum plates were used to add 10 cm of patient equivalent thickness to simulate different body types.

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Objectives: This phantom and animal pilot study aimed to compare image quality and radiation exposure between detector-dose-driven exposure control (DEC) and contrast-to-noise ratio (CNR)-driven exposure control (CEC) as functions of source-to-image receptor distance (SID) and collimation.

Materials And Methods: First, an iron foil simulated a guide wire in a stack of polymethyl methacrylate and aluminum plates representing patient thicknesses of 15, 25, and 35 cm. Fluoroscopic images were acquired using 5 SIDs ranging from 100 to 130 cm and 2 collimations (full field of view, collimated field of view: 6 × 6 cm).

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Purpose: Along with ultrasound, computed tomography (CT) is one of the imaging modalities of choice in patients with suspected diverticular disease (DD). Recently, a newer Classification of Diverticular Disease (CDD) has been proposed. However, its reliability in daily radiological practice has never been proven.

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Article Synopsis
  • Retroperitoneal and rectus sheath hemorrhage (RRSH) is a serious condition that can lead to death, especially in older people or those on blood-thinning medications.
  • The main symptom is abdominal pain, but if there's a lot of bleeding, people may show signs of more severe problems like shock.
  • To treat RRSH, doctors use techniques like surgery and less invasive methods, including checking for bleeding with special scans and working in teams to ensure the best care.
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Article Synopsis
  • Percutaneous hepatic perfusion (PHP) is a treatment for certain liver cancers that uses high doses of a drug called melphalan to attack tumors directly in the liver.
  • The study looked at how reversing the effects of a blood thinner called heparin with another drug, protamine sulfate, affects the number of complications after treatment.
  • Results showed that patients who had full reversal with protamine had more complications, while those with no reversal had fewer serious issues.
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Background Experience with functional CT in the lungs without additional equipment in clinical routine is limited. Purpose To report initial experience and evaluate the robustness of a modified chest CT protocol and photon-counting CT (PCCT) for comprehensive analysis of pulmonary vasculature, perfusion, ventilation, and morphologic structure in a single examination. Materials and Methods In this retrospective study, consecutive patients with clinically indicated CT for various known and unknown pulmonary function impairment (six subgroups) were included between November 2021 and June 2022.

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Background: To report the technique and outcome of ultrasound-guided percutaneous access to the superior mesenteric vein (SMV) for balloon-assisted portal vein recanalization-transjugular intrahepatic portosystemic shunt (PVR-TIPS) in a patient with chronic portal venous and splenic vein occlusion.

Case Presentation: A 51-year-old, non-cirrhotic patient with severe portal hypertension was admitted for PVR-TIPS. Neither splenic nor hepatic access was feasible due to chronic portal and splenic vein occlusion.

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Purpose: Radiology reports mostly contain free-text, which makes it challenging to obtain structured data. Natural language processing (NLP) techniques transform free-text reports into machine-readable document vectors that are important for creating reliable, scalable methods for data analysis. The aim of this study is to classify unstructured radiograph reports according to fractures of the distal fibula and to find the best text mining method.

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Purpose: To retrospectively evaluate the technical and clinical success of interventional treatments employed in three University medical centers and to develop work-flow recommendations for intra-arterial embolizations in patients with life-threatening spontaneous retroperitoneal and rectus sheath hemorrhage (SRRSH).

Materials And Methods: Retrospective evaluation of all patients with contrast-enhanced CT and digital subtraction angiography (DSA) for SRRSH from 01/2018 to 12/2022, amounted to 91 interventions in 83 patients (45f, 38m) with a mean age of 68.1 ± 13.

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Background: Photon-counting detector computed tomography (PCD-CT) has the potential to provide superior image quality compared to energy-integrating detector computed tomography (EID-CT). We compared the two systems for elbow imaging in off-center arm positioning, 90° flexion, and cast fixation in a simulated post-trauma setting.

Methods: The institutional review board approved the study protocol.

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Purpose: To investigate the effect of the ongoing COVID-19 pandemic on interventional radiology (IR) in Germany in 2020 and 2021.

Materials Und Methods: This retrospective study is based on the nationwide interventional radiology procedures documented in the quality register of the German Society for Interventional Radiology and Minimally Invasive Therapy (DeGIR-QS-Register). The nationwide volume of interventions in the pandemic years 2020 and 2021 was compared with the pre-pandemic period (Poisson-test, Mann-Whitney test).

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Cholangiocarcinoma (CCA) are the second most common primary liver tumors and carry a dismal prognosis. Chemosaturation with percutaneous hepatic perfusion (PHP) is a palliative, intra-arterial therapeutic approach that provides a high dose chemotherapy of the liver with reduced systemic exposure. Aim of this retrospective, monocentric study was to analyze PHP as a palliative treatment for unresectable CCA.

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The Identification of Relevant Attributes for Liver Cancer Therapies (IRALCT) project is intended to provide new insights into the relevant utility attributes regarding therapy choices for malignant primary and secondary liver tumors from the perspective of those who are involved in the decision-making process. It addresses the potential value of taking patients' expectations and preferences into account during the decision-making and, when possible, adapting therapies according to these preferences. Specifically, it is intended to identify the relevant clinical attributes that influence the patients', medical laymen's, and medical professionals' decisions and compare the three groups' preferences.

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Purpose: To test the hypothesis of equal or even superior applicability and accuracy of a fully integrated, laser-based computed tomography (CT) navigation system compared with conventional CT guidance for percutaneous interventions.

Materials And Methods: CT-guided punctures were first performed in phantoms. Four radiologists with different experience levels (2 residents (L.

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Background: To evaluate effectivity of a 3D-motion correction algorithm in C-Arm CTs (CACT) with limited image quality (IQ) during transarterial chemoembolization (TACE).

Methods: From 1/2015-5/2021, 644 CACTs were performed in patients during TACE. Of these, 27 CACTs in 26 patients (18 m, 8f; 69.

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With the increasing need for minimally invasive procedures based on lower complication rates, higher patient acceptance, and technical developments, there is a growing focus on the sound interventional training of young radiologists. This survey aimed to analyze the current situation in interventional radiology (IR) training in Germany to detect shortcomings and identify areas for improvement.From November 1-30, 2020, an online questionnaire was distributed to representative radiological associations and societies with the request to forward it to radiology residents and radiologists < 40 years.

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Background: The aim of this animal study was to compare the fluoroscopic image quality (IQ) and radiation dose between a tantalum (Ta)-specific contrast-to-noise ratio-driven exposure control (Ta-CEC) and a detector dose-driven exposure control (DEC) in abdominal angiography.

Methods: Nine angiography scenarios were created in seven anaesthetised pigs using Ta-based embolisation material during percutaneous liver and kidney intervention. Fluoroscopic images were acquired using three DEC protocols with different dose levels and Ta-CEC protocols with different IQ levels, sampled in small steps.

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