Visceral fat area to skeletal muscle mass ratio is linked to albuminuria.

Purpose: Sarcopenic visceral obesity is strongly associated with metabolic dysfunction. We aimed to investigate the association between visceral fat area (VFA) to skeletal muscle mass ratio (VSR) and albuminuria in U.S.

The risk of hyperuricemia assessed by estimated glucose disposal rate.

Purpose: The estimated glucose disposal rate (eGDR) is a simple and noninvasive clinical measure used to assess insulin resistance (IR), yet its potential utility as a marker for hyperuricemia risk had not been systematically evaluated. This study aimed to investigate the relationship between eGDR and hyperuricemia risk among American adults.

Methods: Data for this cross-sectional study were obtained from the 2007-2018 National Health and Nutrition Examination Survey (NHANES).

Insulin resistance assessed by estimated glucose disposal rate and the risk of abdominal aortic calcification: findings from a nationwide cohort study.

Purpose: The estimated glucose disposal rate (eGDR) serves as a straightforward and noninvasive indicator of insulin resistance (IR). This study aims to explore the association between eGDR and the risk of abdominal aortic calcification (AAC).

Methods: We utilized data from adult participants (≥40 years old, n=3006) from the 2013-2014 National Health and Nutrition Examination Survey (NHANES) database.

Intergenerational Solidarity and Mental Health in Chinese American Families: A Dyadic Approach.

Objectives: Existing family and caregiving studies have primarily focused on the mental health of either older adults or adult children. Less is known about the effect of intergenerational relations on the mental health of both generations. This study examined the association between intergenerational solidarity and mental health among older Chinese Americans and their adult children using a dyadic analysis, considering the gendered nature of these relationships.

Relationships between physical frailty and cognitive decline over 8 years: A longitudinal study among community-dwelling older Chinese immigrants.

Objectives: To examine patterns of physical frailty changes, their sociocultural correlates, and associations with initial cognitive functioning and cognitive decline over an eight-year observation period among community-dwelling older Chinese immigrants.

Design: An 8-year follow-up longitudinal study.

Setting And Participants: 2,835 community-dwelling adults aged 60 and above living in Chicago, who self-identified as Chinese, with a mean age of 72.

Trust in Physicians and End-of-Life Discussions and Preferences for Place of Care Among US Chinese Older Adults.

Background: Patient trust in physicians is essential for effective end-of-life discussions. Little is known about how Chinese older adults' trust in physicians relates to their end-of-life care discussions and care setting preferences.

Objective: To examine the association between medical trust among Chinese older adults and their views on end-of-life discussions and care setting preferences.

Sleep quality and cognitive functioning among Chinese older adults living in the US: a mixed-effects model analysis.

Background: Racial and ethnic disparities in sleep quality and cognitive health are increasingly recognized, yet little is understood about their associations among Chinese older adults living in the United States. This study aims to examine the relationships between sleep health and cognitive functioning in this population, utilizing data from the Population Study of Chinese Elderly in Chicago (PINE).

Methods: This observational study utilized a two-wave panel design as part of the PINE, including 2,228 participants aged 65 years or older who self-identified as Chinese.

Composite dietary antioxidant index and obesity among U.S. adults in NHANES 2007-2018.

Antioxidant-rich diets serve as protective factors in preventing obesity. The composite dietary antioxidant index (CDAI) represents a novel, comprehensive metric for assessing the antioxidant capacity of diets. Our objective is to investigate the relationship between the CDAI and obesity prevalence among adults in the United States.

Composite dietary antioxidant index and abdominal aortic calcification: a national cross-sectional study.

Purpose: The Composite Dietary Antioxidant Index (CDAI) is a novel, inclusive measure for evaluating the antioxidant potential of diets. We aim to explore the link between the CDAI and abdominal aortic calcification (AAC) in U.S.

Impacts of Acculturation on Depressive Symptoms and Activities of Daily Living of U.S. Older Chinese Immigrants.

Background And Objectives: Acculturation is a critical aspect of social experience for immigrants, including Asian immigrants. Existing literature has shown mixed findings on the health impacts of acculturation and largely relied on cross-sectional studies, preventing drawing definitive conclusions. This study aimed to examine the long-term effects of acculturation on depressive symptoms and activities of daily living (ADL) limitations in a large sample of older Chinese immigrants in the United States.

Association between the atherogenic index of plasma and kidney stones: a nationally representative study.

Purpose: The atherogenic index of plasma (AIP) is a novel comprehensive lipid index. We aimed to investigate a possible relationship between AIP index and kidney stones in US adults.

Methods: This cross-sectional study was conducted among adults with complete AIP index and questionnaire records on kidney stones from the National Health and Nutrition Examination Survey (NHANES) spanning from 2007 to 2018.

The relationship between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hyperuricaemia.

Purpose: The ratio of non-high-density lipoprotein cholesterol (non-HDL-c) to high-density lipoprotein cholesterol (HDL-c) (NHHR) is a novel comprehensive lipid index. The aim of this study was to investigate the relationship between the NHHR and the prevalence of hyperuricaemia (HUA) in the adult population of the U.S.

Causal relationships between gut microbiota, gut metabolites, and diabetic neuropathy: A mendelian randomization study.

Background: Previous studies have shown a strong correlation between gut microbiota and diabetes and its associated complications. We aimed to evaluate the causal relationships between the gut microbiota, gut metabolites, and diabetic neuropathy.

Methods: Summary statistics of 211 gut microbiota and 12 gut-related metabolites (β-hydroxybutyric acid, betaine, trimethylamine-N-oxide, carnitine, choline, glutamate, kynurenine, phenylalanine, propionic acid, serotonin, tryptophan, and tyrosine) were obtained from previous genome-wide association studies (GWAS).

Reduced sensitivity to thyroid hormones is associated with lung function in euthyroid individuals.

Background: The thyroid gland exhibits a subtle interconnection with the lungs. We further investigated the correlation between thyroid hormone sensitivity and lung function in euthyroid individuals.

Methods: Data on spirometry and mortality for participants aged 19-79 years were extracted from the NHANES database.

Impaired sensitivity to thyroid hormones is associated with albuminuria in the euthyroid population: results from NHANES.

Purpose: The relationship between thyroid hormone sensitivity and albuminuria remains unclear. We aimed to investigate the association between thyroid hormone sensitivity and the risk of albuminuria in a euthyroid population.

Methods: This cross-sectional study included 7634 euthyroid adults collected from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2012.

Identification of Senescence-Associated Biomarkers in Diabetic Glomerulopathy Using Integrated Bioinformatics Analysis.

Background: Cellular senescence is thought to play a significant role in the onset and development of diabetic nephropathy. The goal of this study was to explore potential biomarkers associated with diabetic glomerulopathy from the perspective of senescence.

Methods: Datasets about human glomerular biopsy samples related to diabetic nephropathy were systematically obtained from the Gene Expression Omnibus database.

Co-treatment of Astragaloside IV with Vitamin D in Diabetic Peripheral Neuropathic Rats: Protective Effects and Potential Mechanisms.

Objective: The potential mechanism underlying the protective effect of Astragaloside IV (AS-IV) co-treatment with 1, 25-dihydroxy-vitamin D (Vit-D) on neuropathy in diabetic high-fat rats was investigated.

Methods: The rat diabetic hyperlipidemia (DH) model was established via streptozotocin and a high-fat diet (HFD). After co-treatment (of AS-IV and Vit-D at respective doses of 50 mg/kg via oral gavage and 30000 IU/kg via intramuscular injection), blood glucose levels, markers of inflammation and oxidative stress, as well as apoptosis and histopathology were evaluated with appropriate techniques.

Causal relationships between gut microbiota and hypothyroidism: a Mendelian randomization study.

Background: Previous studies have shown that the gut microbiota plays an important role in the maintenance of thyroid homeostasis. We aimed to evaluate the causal relationships between gut microbiota and hypothyroidism.

Methods: Summary statistics for 211 gut microbiota taxa were obtained from the largest available genome-wide association study (GWAS) meta-analysis conducted by the MiBioGen consortium.