Systematic review: The integration of artificial intelligence-powered cognitive-behavioural therapy for autonomous mental health management.

Background: Depression is a widespread mental health disorder that affects quality of life, with traditional treatments often resource-intensive. Studies have demonstrated the effectiveness of CBT-based AI in alleviating depressive symptoms through autonomous mental health management.

Purpose: To evaluate the effect and the integration level of Cognitive-Behavioural Therapy-based artificial intelligence (AI) on autonomous health management in depressive symptoms care.

Amateurs exhibit greater psychomotor efficiency than novices: evidence from EEG during a visuomotor task.

Introduction: The goal of this study was to examine the neural activities, which contribute to performance efficiency in the early stages of motor skill learning, such as amateur versus novice. To achieve this goal, electroencephalography (EEG) was employed to compare the differences in EEG power that can be used to assess neural excitability between amateur and novice golfers during a visuomotor task (i.e.

Neuromotor mechanisms of successful football penalty kicking: an EEG pilot study.

Introduction: Understanding the neuromotor processes underlying successful and unsuccessful performance in lower limb movements, such as football kicking, is essential for athletes. However, further investigation is needed to determine whether lower activation of the prefrontal and central cortices, which are associated with motor programming, such as motor planning and motor control, corresponds to higher degrees of psychomotor performance in a difficult task. To address this issue, this within-subject pilot study aimed to investigate neuromotor processes in skilled football players performing penalty kicks under a difficult condition.

Metabolic and immune heterogeneity in stroke: Insights into subtype identification and biomarker discovery.

Stroke is a leading cause of mortality and long-term disability worldwide, characterized by substantial molecular and clinical heterogeneity. This study aimed to investigate the metabolic and immune-related mechanisms underlying stroke subtypes using transcriptomic data and advanced computational tools. Gene expression data from two GEO datasets (GSE16561 and GSE58294) were preprocessed, batch-corrected, and integrated.

Fall-Risk Monitoring in Diverse Terrains Using Dual-Task Learning and Wearable Sensing System.

As the elderly population grows, falling accidents become more frequent, and the need for fall-risk monitoring systems increases. Deep learning models for fall-risk movement detection neglect the connections between the terrain and fall-hazard movements. This issue can result in false alarms, particularly when a person encounters changing terrain.

Transperineal Magnetic Resonance Imaging-Fusion Targeted Prostate Biopsy Utilizing the PrecisionPoint Transperineal Access System vs a Grid Template: An Assessment of Outcomes.

Objective: To compare PrecisionPoint and grid-based biopsies on rates of clinically significant prostate cancer (csPCa) detection and complications when transperineal MRI-fusion targeted biopsy is performed.

Materials And Methods: We queried a prospectively maintained prostate biopsy database to identify men ages 18-89 who underwent transperineal MRI-fusion targeted prostate biopsies (including concurrent systematic biopsies) between August 1, 2020 and September 1, 2024. The primary outcome was detection of csPCa in the MRI region of interest.

Feasibility and safety of Taipei Veterans General Hospital Heavy Ion Therapy Center: The first carbon-ion irradiation facility in Taiwan.

Background: Unlike conventional photon radiotherapy, particle therapy has the advantage of dose distribution. Carbon-ion radiotherapy is also advantageous in terms of biological effectiveness and other radiobiological aspects. These benefits lead to a higher response probability for previously known radioresistant tumor types.

Rise of long-distance urology transfer during the COVID-19 pandemic: Identifying factors to enhance transfers of care efficiency and clinical outcomes.

Objective: The objective of this study is to identify variables associated with clinical outcomes after urologic transfers before and during the COVID pandemic.

Methods: After IRB approval, a retrospective chart review was performed on adult patients transferred to our institution from 01/01/2018 to 12/31/2019 ("pre-COVID") and from 01/02/2020 to 12/31/2022 ("COVID"). We identified demographics, origin hospitals, ICD-10 pre- and post-transfer diagnoses, distance of transfer, and post-transfer CPT codes.

Multispectral Imaging-Based System for Detecting Tissue Oxygen Saturation With Wound Segmentation for Monitoring Wound Healing.

Objective: Blood circulation is an important indicator of wound healing. In this study, a tissue oxygen saturation detecting (TOSD) system that is based on multispectral imaging (MSI) is proposed to quantify the degree of tissue oxygen saturation (StO2) in cutaneous tissues.

Methods: A wound segmentation algorithm is used to segment automatically wound and skin areas, eliminating the need for manual labeling and applying adaptive tissue optics.

[Experience of Providing Intensive Rehabilitation Care to a School-Aged Child With Living-Donor Lobar Lung Transplantation].

The post-operative intensive care experience of a school-aged child who received living-donor bilateral lobar lung transplantation due to acute respiratory distress syndrome and interstitial pulmonary fibrosis is discussed in this paper. The patient received lungs donated by her parents in a "living-donor bilateral lobar lung transplantation" due to severe lung function impairment. The patient felt anxious due to her long-term hospitalization for preoperative evaluation, various invasive treatments, and postoperative rehabilitation.

Outcomes of acute ischemic stroke among patients with renal cell carcinoma: A nationwide analysis.

Introduction: Renal cell carcinoma (RCC) has been associated with an increased risk for acute ischemic stroke (AIS). As individuals with cancer who experience AIS tend to face higher mortality rates compared to AIS patients without cancer, recognizing the implications of RCC in AIS is crucial for identifying high-risk patients for major complications and directing management strategies.

Objective: To examine risk factors, interventions, and outcomes for patients with AIS stratified by their RCC diagnosis.

Managing type 1 diabetes of a child: Parents' perspectives.

Purpose: Managing type 1 diabetes (T1D) challenges children and their parents. Parents need to learn the necessary skills and later transfer the responsibility of care to their children as they develop. The transition process involves autonomy in behaviour and decision-making.

A gap in the data: Defining, identifying, and tracking children with medical complexity in the child welfare system.

Background: Among nearly 400,000 children in US foster care, an estimated 10 % are medically complex. Yet, population-level data about children with medical complexity (CMC) served by the child welfare system, both for prevention and foster care services, are largely unavailable.

Objective: To understand how US child welfare agencies define, identify, and track CMC.

A double-hit: End-stage renal disease patients suffer worse outcomes in intracerebral hemorrhage.

Background: Intracerebral hemorrhage (ICH) carries significant morbidity and mortality. Previous single-center retrospective analysis suggests that end-stage renal disease (ESRD) is a risk factor for severe ICH and worse outcomes. This investigation aims to examine the impact of ESRD on ICH severity, complications, and outcomes using a multicenter national database.

Frailty as a Predictor of Outcomes in Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis.

Frailty is an emerging concept in clinical practice used to predict outcomes and dictate treatment algorithms. Frail patients, especially older adults, are at higher risk for adverse outcomes. Aneurysmal subarachnoid hemorrhage (aSAH) is a neurosurgical emergency associated with high morbidity and mortality rates that have previously been shown to correlate with frailty.

Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions.

The tumor microenvironment (TME) is known to direct cancer cell growth, migration, invasion into the matrix and distant tissues, and to confer drug resistance in cancer cells. While multiple aspects of TME have been studied using , , and tumor models and engineering tools, the influence of matrix viscoelasticity on pancreatic cancer cells and its associated TME remained largely unexplored. In this contribution, we synthesized a new biomimetic hydrogel with tunable matrix stiffness and stress-relaxation for evaluating the effect of matrix viscoelasticity on pancreatic cancer cell (PCC) behaviors .

Association of grit and overall survival in patients undergoing nephrectomy for renal cell carcinoma.

Background: Quantifying grit with the Short Grit Scale (Grit-S) has shown ability to predict success in various academic and professional domains. Grit has yet to be analyzed in patients with cancer.

Methods: This study is a longitudinal analysis of prospectively distributed Grit-S surveys to patients undergoing radical or partial nephrectomy.

Dissolvable microgel-templated macroporous hydrogels for controlled cell assembly.

Mesenchymal stem cells (MSCs)-based therapies have been widely used to promote tissue regeneration and to modulate immune/inflammatory response. The therapeutic potential of MSCs can be further improved by forming multi-cellular spheroids. Meanwhile, hydrogels with macroporous structures are advantageous for improving mass transport properties for the cell-laden matrices.

Low free testosterone is associated with increased mortality in frail surgical patients.

Background: Preoperative frailty has been associated with adverse postoperative outcomes. Additionally, low testosterone has been associated with physical frailty and cognitive decline. However, the impact of simultaneous frailty and low testosterone on surgical outcomes is understudied.

Injectable Acylhydrazone-Linked RAFT Polymer Hydrogels for Sustained Protein Release and Cell Encapsulation.

A new class of temperature responsive polymer, termed PADO, is synthesized by reversible addition-fragmentation chain-transfer polymerization. Synthesized from copolymerization of diacetone acrylamide (DAAM), di(ethylene glycol) ethyl ether acrylate, and oligo(ethylene glycol) methyl ether acrylate, PADO polymer phase separates at temperature above its lower critical solution temperature (36-42 °C) due to enhanced hydrophobic interactions between the short ethylene glycol side chains. Solution of PADO polymers exhibit injectable shear-thinning properties and reach sol-gel transition rapidly (<5 min) at 37 °C.

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos.

Body composition is associated with risk of disease progression and treatment complications in a variety of conditions. Therefore, quantification of skeletal muscle mass and adipose tissues on Computed Tomography (CT) and/or Magnetic Resonance Imaging (MRI) may inform surgery risk evaluation and disease prognosis. This article describes two quantification methods originally described by Mourtzakis et al.

Facile Synthesis of Rapidly Degrading PEG-Based Thiol-Norbornene Hydrogels.

An alternate synthesis route was developed to prepare norbornene-functionalized poly(ethylene glycol) (PEG) from reacting multiarm PEG with carbic anhydride. The macromer, PEGNB, permits photo-cross-linking of thiol-norbornene hydrogels with kinetics comparable to conventional PEGNB macromer. In addition, PEGNB provides an additional carboxylate group for further conjugation with amine-bearing molecules.

Polystyrene--Polydimethylsiloxane as a Potential Silica Substitute for Polysiloxane Reinforcement.

Here we report microphase-separated poly(styrene--dimethylsiloxane) (PS--PDMS) as a reinforcing filler in PDMS thermosets that overcomes the long-standing problem of aging in the processing of silica-reinforced silicone. Surprisingly, PS--PDMS reinforced composites display comparable mechanical performance to silica-modified analogs, even though the modulus of PS is much smaller than that of silica and there is no evidence of percolation with respect to the rigid PS domains. We have found that a few unique characteristics contribute to the reinforcing performance of PS--PDMS.

In Situ Formed PtTi Nanoparticles on a Two-Dimensional Transition Metal Carbide (MXene) Used as Efficient Catalysts for Hydrogen Evolution Reactions.

The design of efficient catalysts capable of delivering high currents at low overpotentials for hydrogen evolution reactions (HERs) is urgently needed to use catalysts in practical applications. Herein, we report platinum (Pt) alloyed with titanium (Ti) from the surface of TiCT MXenes to form PtTi intermetallic compound (IMC) nanoparticles (NPs) via in situ coreduction. In situ X-ray absorption spectroscopy (XAS) indicates that Pt undergoes a temperature-dependent transformation from single atoms to intermetallic compounds, and the catalyst reduced at 550 °C exhibits a superior HER performance in acidic media.